Ivabid Od 10 Mg Tablet

IVABID OD 10 MG TABLET by ABBOTT

IVABID OD 10 MG TABLET is a medication designed to manage certain heart conditions by specifically lowering the heart rate. The "OD" in its name signifies a "Once Daily" long-acting formulation for convenient dosing.

• Name:

  • Brand Name: IVABID OD 10 MG TABLET
  • Common Name: Ivabradine

• Composition:

  • Each tablet contains Ivabradine 10 mg as the active ingredient.

• Uses: IVABID OD 10 MG TABLET is prescribed for the treatment of:

  • Chronic Heart Failure: It helps to reduce hospitalizations and improve prognosis in adult patients with stable, symptomatic chronic heart failure, particularly those with reduced left ventricular ejection fraction and an elevated resting heart rate (typically ≥ 75 beats per minute).
  • Stable Angina (Chest Pain): It is used for the symptomatic treatment of chronic stable angina pectoris in adults with normal sinus rhythm and a heart rate ≥ 70 beats per minute, especially when beta-blockers are not tolerated, contraindicated, or provide insufficient control. It works by reducing the heart's oxygen demand and improving blood flow to the heart muscle, leading to fewer angina attacks and improved exercise tolerance.

• Dosage and Administration:

  • IVABID OD 10 MG TABLET is typically taken orally once daily with food.
  • The dose may be adjusted by a doctor based on the patient's heart rate and tolerability, aiming for a resting heart rate between 50 and 60 beats per minute.
  • Do not crush or chew the tablet; swallow it whole with a glass of water.
  • It's important not to abruptly discontinue the medication without consulting a doctor, as this may worsen the condition.

• Side Effects:

  • Common Side Effects: Slow heart rate (bradycardia), visual disturbances (phosphenes, luminous phenomena, or temporary brightness/flashes in vision), dizziness, headache, fatigue, blurred vision, and high blood pressure. Visual disturbances often occur within the first two months of treatment and may gradually subside.
  • Serious Side Effects: Atrial fibrillation (irregular or rapid heartbeat), severe headache, pounding in the ears, fainting, significant changes to heartbeat, and allergic reactions.

• Precautions:

  • Contraindications: Do not use if you have a resting heart rate below 60 bpm before treatment, severe liver impairment, acute decompensated heart failure, cardiogenic shock, severe hypotension (very low blood pressure), or certain heart rhythm disorders (e.g., sick sinus syndrome, third-degree AV block) unless a pacemaker determines the heart rate.
  • Pregnancy and Breastfeeding: Not recommended during pregnancy as it may harm the unborn baby, and effective birth control methods should be used. Avoid during breastfeeding unless absolutely necessary.
  • Drug Interactions: Inform your doctor about all medications you are taking, including over-the-counter and herbal products. Ivabradine should not be taken with potent inhibitors of CYP3A4 (e.g., clarithromycin, itraconazole, ketoconazole, nefazodone, nelfinavir, telithromycin). Concomitant use with drugs that slow heart rate (e.g., beta-blockers, digoxin, amiodarone) may increase the risk of bradycardia. Avoid or limit grapefruit juice intake, as it may affect drug metabolism.
  • Other Warnings: Use with caution in patients with low blood pressure, severe kidney disease, or certain eye conditions. Monitor heart rate regularly during treatment. Avoid driving or operating machinery if you experience dizziness or visual disturbances.

• Storage:

  • Store at room temperature, ideally between 20°C to 25°C (68°F to 77°F).
  • Keep out of the reach of children.

Here are frequently asked questions about IVABID OD 10 MG TABLET:

What is IVABID OD 10 MG Tablet used for?

IVABID OD 10 MG Tablet, containing the active ingredient Ivabradine, is primarily used to treat adults with chronic stable angina (heart-related chest pain) and chronic heart failure. It helps reduce the risk of hospitalization for worsening heart failure. It is prescribed when beta-blockers are not tolerated, contraindicated, or do not provide adequate symptom control.

How does IVABID OD 10 MG Tablet work?

IVABID OD 10 MG Tablet works by selectively inhibiting the "funny" (I(f)) current in the heart's sinoatrial (SA) node, which is the natural pacemaker. By blocking this channel, it slows down the heart rate without affecting the heart's pumping strength (contractility) or blood pressure. This reduction in heart rate decreases the heart's workload and oxygen demand, improving blood flow to the heart muscle and alleviating symptoms like chest pain.

What is the usual dosage for IVABID OD 10 MG Tablet?

The recommended starting dose for adults is typically 5 mg twice daily with food. The dose can be adjusted after two weeks based on the patient's resting heart rate and how well they tolerate the medication, aiming for a heart rate between 50 and 60 beats per minute (bpm). The maximum recommended dose is 7.5 mg twice daily. Your doctor will determine the appropriate dose for you.

What are the possible side effects of IVABID OD 10 MG Tablet?

Common side effects can include slow or irregular heartbeats (bradycardia), visual disturbances such as temporary brightness in the field of vision (phosphenes), headache, dizziness, and high blood pressure. More serious, but less common, side effects can include atrial fibrillation (an irregular heart rhythm). If you experience any severe or persistent side effects, contact your doctor immediately.

Is IVABID OD 10 MG Tablet safe during pregnancy or breastfeeding?

IVABID OD 10 MG Tablet (Ivabradine) is contraindicated during pregnancy due to potential risks to the unborn baby, as animal studies have shown reproductive toxicity. Women of childbearing potential should use reliable contraception during treatment. It is also not recommended during breastfeeding because animal studies indicate that Ivabradine is excreted in milk, and the effects on nursing infants are unknown.

Can IVABID OD 10 MG Tablet be taken with other medications?

No, IVABID OD 10 MG Tablet should not be taken with certain medications, especially strong CYP3A4 inhibitors (e.g., ketoconazole, itraconazole, clarithromycin, HIV protease inhibitors like nelfinavir, nefazodone) and some calcium channel blockers (e.g., diltiazem, verapamil), as these can significantly increase ivabradine levels and risk of bradycardia. Concomitant use with other drugs that slow the heart rate (e.g., digoxin, amiodarone, beta-blockers) should be carefully monitored due to an increased risk of bradycardia. It is crucial to inform your doctor about all prescription, over-the-counter medications, vitamins, and herbal products, including St. John's wort, you are taking.

What precautions should be taken while taking IVABID OD 10 MG Tablet?

You should not use this medicine if you have a resting heart rate below 70 bpm before treatment, cardiogenic shock, certain heart rhythm disorders (e.g., sick sinus syndrome, 3rd-degree AV block without a pacemaker), very low blood pressure, unstable angina, or severe liver problems. Avoid grapefruit and grapefruit juice while on this medication, as it can affect how the medicine is absorbed. Use caution when driving or operating machinery, especially at night or in places with sudden light changes, as temporary visual disturbances (luminous phenomena) may occur. Your doctor will monitor your heart rate and overall progress regularly.

What happens if a dose of IVABID OD 10 MG Tablet is missed?

If you miss a dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.

How should IVABID OD 10 MG Tablet be stored?

Store IVABID OD 10 MG Tablet in its closed container at room temperature, generally between 68°F to 77°F (20°C to 25°C), away from heat, moisture, and direct light. Keep it out of the reach of children.