Eglucent Mix50 Cartridge

EGLUCENT MIX50 CARTRIDGE

Name

• Brand Name: Eglucent Mix 50 100IU/ml Suspension for Injection Cartridge
• Common Name: Biphasic Insulin Lispro

Composition Eglucent Mix 50 Cartridge contains a pre-mixed combination of active ingredients:

• Insulin Lispro (50%)
• Insulin Lispro Protamine (50%)

Uses This medication is prescribed for the treatment of both Type 1 and Type 2 Diabetes Mellitus. It works by combining a fast-acting insulin (Insulin Lispro) with an intermediate-acting insulin (Insulin Lispro Protamine) to provide rapid and sustained blood sugar control, helping to lower blood sugar levels after meals and reduce the risk of diabetes-related complications.

Dosage and Administration Eglucent Mix 50 Cartridge is administered via subcutaneous injection. It should be taken either 15 minutes before a meal or within 20 minutes after starting a meal. Injection sites (such as the abdomen, thighs, upper arms, or buttocks) should be rotated to prevent skin damage. It should not be injected directly into a vein or muscle. The dosage is determined by a healthcare provider and should not be discontinued without medical advice.

Side Effects Common side effects may include:

• Low blood sugar levels (hypoglycemia), which can manifest as dizziness, lightheadedness, anxiety, sweating, hunger, and visual disturbances
• Injection site reactions (pain, redness, swelling, itching, or thickening of the skin)
• Lipodystrophy (shrinkage of fat tissues beneath the skin) or lumps under the skin
• Weight gain
• Swelling (edema)

Serious side effects, though rare, can include severe allergic reactions (anaphylactic shock) and severe hypoglycemia.

Precautions

• Hypoglycemia: Do not use if you have low blood sugar levels. Always carry a quick source of sugar.
• Pregnancy and Breastfeeding: Consult a doctor as dose adjustments may be necessary.
• Medical Conditions: Inform your doctor about any kidney, liver, or heart problems, or hormonal issues.
• Alcohol: Avoid alcohol consumption as it can interfere with insulin's action and increase the risk of low or high blood sugar.
• Driving: Exercise caution as insulin can cause low blood sugar, affecting alertness.
• Do not share needles or insulin devices.

Storage Eglucent Mix 50 Cartridge should be stored in a refrigerator at 2-8°C. Do not freeze. Unopened cartons should be protected from light. Once opened, cartridges can be stored at room temperature (up to 25°C) for up to 4 weeks. Any unused portion should be discarded appropriately.

EGLUCENT MIX50 CARTRIDGE by LUPIN LTD is an injectable medication used for the management of diabetes mellitus. It contains a combination of fast-acting and intermediate-acting insulin to help control blood sugar levels in both Type 1 and Type 2 diabetes.

What is EGLUCENT MIX50 CARTRIDGE used for?

EGLUCENT MIX50 CARTRIDGE is used to improve blood sugar control in adults and children with Type 1 and Type 2 diabetes mellitus. It helps the body utilize glucose for energy production and regulate blood glucose levels.

How does EGLUCENT MIX50 CARTRIDGE work?

EGLUCENT MIX50 CARTRIDGE contains Biphasic Insulin Lispro, which is a pre-mixed combination of Insulin Lispro (fast-acting) and Insulin Lispro Protamine (intermediate-acting). Insulin Lispro quickly lowers blood sugar levels after meals, while Insulin Lispro Protamine provides a more sustained effect to manage blood sugar between meals and overnight. This combination works by stimulating glucose uptake by cells, tissues, and muscles, and by inhibiting glucose production in the liver.

What is the usual dosage for EGLUCENT MIX50 CARTRIDGE?

The dosage of EGLUCENT MIX50 CARTRIDGE is determined by your doctor and should be strictly followed. It is typically administered as an injection under the skin (subcutaneously) in areas like the abdomen, upper arms, thighs, or buttocks. It should be taken 15 minutes before a meal or within 20 minutes after starting a meal. Injection sites should be rotated to prevent lumps from forming.

What are the possible side effects of EGLUCENT MIX50 CARTRIDGE?

The most common side effect is low blood sugar (hypoglycemia), which can manifest as lightheadedness, dizziness, anxiety, nervousness, tiredness, feeling hungry, visual disturbances, headache, shaking, sweating, or pale skin. Other possible side effects include injection site reactions (pain, redness, swelling, itching), skin rashes, weight gain, swelling (edema), lipodystrophy (skin thickening or pits at the injection site), and in rare cases, severe allergic reactions.

Is EGLUCENT MIX50 CARTRIDGE safe during pregnancy or breastfeeding?

EGLUCENT MIX50 CARTRIDGE can be used during pregnancy if recommended by your doctor, though close monitoring of blood sugar levels is suggested as dose requirements may change. It should be used with caution in breastfeeding women, and adjustments in insulin dose or diet may be required.

Can EGLUCENT MIX50 CARTRIDGE be taken with other medications?

EGLUCENT MIX50 CARTRIDGE can interact with several medications. Some medicines, such as other diabetes medications, certain antidepressants, salicylates, ACE inhibitors, and beta-blockers, may increase the risk of low blood sugar. Conversely, medications like oral contraceptives, steroids, and thyroid hormones can lead to high blood sugar. It's crucial to inform your doctor about all medications you are taking, including over-the-counter drugs and herbal supplements, to avoid potential interactions.

What precautions should be taken with EGLUCENT MIX50 CARTRIDGE?

It's important to be aware of the symptoms of low blood sugar (hypoglycemia) and always carry a source of sugar (like glucose tablets or candy) for immediate relief. Caution is advised if you have recurrent low blood sugar levels, liver or kidney diseases, heart problems (especially with certain other diabetes medications like thiazolidinediones), or thyroid disorders. Alcohol consumption should be avoided as it can interfere with insulin's action and increase the risk of both low and high blood glucose. You should never share your insulin device with others.

What happens if a dose of EGLUCENT MIX50 CARTRIDGE is missed?

If you miss a dose of EGLUCENT MIX50 CARTRIDGE, take it as soon as you remember. However, if it's almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to compensate for the missed one, as this can cause a drastic and dangerous fall in blood glucose levels.

How should EGLUCENT MIX50 CARTRIDGE be stored?

Unopened EGLUCENT MIX50 CARTRIDGE should be stored in a refrigerator between 2°C to 8°C. Do not freeze it, and protect it from light by keeping it in its outer carton. Once opened or in use, the cartridge can be kept at room temperature (below 25°C or as per specific product instructions) for up to 4 weeks.