Pregalin Gel

PREGALIN GEL

PREGALIN GEL, manufactured by TORRENT PHARMACEUTICALS LTD, is a topical medication designed for targeted pain relief.

• Name:

  • Brand Name: PREGALIN GEL
  • Common Name: Pregabalin Gel

• Composition:

  • Active Ingredient: Pregabalin 8% w/w
  • Excipients: Cetostearyl alcohol, Cetomacrogol 1000, Light Liquid Paraffin, White Soft Paraffin, Propylene glycol, Disodium EDTA, Acrypol 980, Butylated hydroxyl toluene, Methyl paraben, Propyl paraben, Triethanolamine.

• Uses: PREGALIN GEL is primarily used for the treatment of diabetic neuropathic pain. It works by reducing nerve sensitivity and calming overactive pain signals, providing localized relief from burning, tingling, and shooting pain. It may also be used to treat other forms of neuropathic pain and, in some cases, can be prescribed for seizures or anxiety.

• Dosage and Administration: Apply a thin film of the gel over the affected area twice a day, or as directed by a physician. Ensure the skin is clean and dry before application.

• Side Effects: While PREGALIN GEL is generally well-tolerated with minimal systemic absorption, some side effects associated with the active ingredient pregabalin (especially in oral forms) include:

  • Common: Sleepiness, weight gain, dryness in mouth, blurred vision, dizziness, and peripheral edema (swelling).
  • Serious: Immediately discontinue use and seek medical help if you experience swelling of the throat, hives, or difficulty breathing, as these may indicate serious allergic reactions. Oral pregabalin can also be associated with suicidal thoughts or behavior, and vision changes.

• Precautions:

  • Avoid using if you have known allergies to Pregabalin or any of its ingredients.
  • Consult your doctor about all other medications you are taking, including over-the-counter, vitamins, and herbal products, to avoid potential interactions, although systemic absorption of the gel is minimal.
  • Pregnant and breastfeeding women should consult their doctor before use.
  • Avoid consuming alcohol as it may cause excessive sleepiness or drowsiness if any systemic absorption occurs.
  • Inform your doctor promptly if you notice any vision changes, unusual changes in mood or behavior, new or worsening depression, or suicidal thoughts.
  • Do not stop taking the medication suddenly without consulting your doctor, as this may worsen underlying conditions.
  • Patients with diabetes should pay extra attention to their skin and report any sores, redness, or skin problems to their doctor.

• Storage: Store PREGALIN GEL in a cool and dry place, below 30°C. Do not freeze and protect it from direct sunlight. Keep out of sight and reach of children.

PREGALIN GEL, manufactured by Torrent Pharmaceuticals Ltd., is a topical medication primarily used for pain management. It contains Pregabalin as its active ingredient.

What is PREGALIN GEL used for?

PREGALIN GEL is primarily used for the treatment of neuropathic pain, specifically diabetic neuropathic pain. Neuropathic pain is caused by damage or dysfunction of the nervous system, leading to sensations like burning, tingling, or shooting pain.

How does PREGALIN GEL work?

PREGALIN GEL works by modulating the calcium channel activity of nerve cells. It is hypothesized that the topical application of Pregabalin may increase the synthesis of Nitric Oxide and promote the release of endogenous opioids, which helps to attenuate neuropathic pain. This action helps to reduce nerve sensitivity and calm overactive pain signals in the affected area.

What is the usual dosage for PREGALIN GEL?

PREGALIN GEL should be applied as a thin film over the affected area twice a day, or as directed by a physician. It is important to wash your hands thoroughly after application.

What are the possible side effects of PREGALIN GEL?

As PREGALIN GEL is a topical application with minimal absorption into the bloodstream, the risk of systemic side effects is expected to be low. However, localized side effects at the application site may include skin irritation, allergic reactions, redness, dry skin, or a burning or tingling sensation. Systemic side effects associated with oral Pregabalin, such as dizziness, decreased sexual interest, flatulence, tingling, dry mouth, loss of memory, weight gain, or double vision, are less likely with the topical gel but are listed as general Pregabalin side effects.

Is PREGALIN GEL safe during pregnancy or breastfeeding?

PREGALIN GEL should generally be avoided during pregnancy, especially in the first trimester, as it may cause fetal harm. If you are pregnant or planning to become pregnant, consult your doctor. Breastfeeding is not recommended while using PREGALIN GEL.

Can PREGALIN GEL be taken with other medications?

Due to the minimal systemic absorption of Pregabalin from the topical gel, significant drug interactions are not commonly reported. However, it is always advisable to inform your doctor about all medications you are taking, including other topical products, to rule out any potential interactions.

What precautions should be taken while using PREGALIN GEL?

Do not use PREGALIN GEL if you have a known hypersensitivity to Pregabalin or any of its components. Avoid applying the gel on broken, irritated, or damaged skin. Use with caution in older adults, especially if they have sensitive or thin skin. Discontinue use immediately and seek emergency treatment if you experience signs of angioedema (e.g., swelling of the throat, head, and neck) or other hypersensitivity reactions (e.g., hives, difficulty breathing). PREGALIN GEL is not recommended for use in children without medical supervision.

What happens if a dose of PREGALIN GEL is missed?

If you miss a dose of PREGALIN GEL, apply it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not apply a double dose to make up for a missed one.

How should PREGALIN GEL be stored?

PREGALIN GEL should be stored at room temperature, typically between 20-25°C. Keep it away from direct sunlight and moisture, and do not freeze the gel. Ensure it is kept out of reach of children.