K Glim 1 Tablet

K GLIM 1 TABLET

K GLIM 1 TABLET is an oral anti-diabetic medication manufactured by BLUE CROSS LABORATORIES LTD, primarily used for the management of Type 2 Diabetes Mellitus in adults.

• Composition K GLIM 1 TABLET contains Glimepiride 1 mg as its active ingredient. Glimepiride belongs to a class of medicines known as sulfonylureas.

• Uses K GLIM 1 TABLET is prescribed to lower high blood sugar levels in adults with Type 2 Diabetes Mellitus, especially when diet and exercise alone are insufficient to achieve adequate glycemic control. It helps prevent diabetes-related complications such as kidney damage, eye problems, and nerve issues. This medicine may also be used in conjunction with insulin or other anti-diabetic medications like metformin for improved blood sugar control. Glimepiride works by stimulating the beta cells in the pancreas to release more insulin and enhancing the body's sensitivity to insulin, which helps glucose move from the blood into the cells for energy.

• Dosage and Administration K GLIM 1 TABLET should be taken orally, once daily, usually shortly before or with the first main meal of the day (typically breakfast). It should be swallowed whole with a glass of water and not crushed, broken, or chewed.

  • Initial Dose: The recommended starting dose is 1 mg or 2 mg once daily.
  • Patients at Higher Risk of Hypoglycemia (e.g., elderly, renal impairment): A starting dose of 1 mg once daily is advised.
  • Maintenance Dose: The usual maintenance dose is 1–4 mg once daily.
  • Maximum Dose: The maximum recommended dose is 8 mg once daily.
  • Dosage increases should not exceed 2 mg at 1- to 2-week intervals, based on blood glucose levels. It is crucial to maintain regular meal schedules and not skip meals to prevent low blood sugar.

• Side Effects Common side effects of K GLIM 1 TABLET include:

  • Low blood sugar levels (hypoglycemia), characterized by sweating, dizziness, headache, shaking, increased hunger, weakness, and confusion.
  • Nausea.
  • Headache.
  • Dizziness.
  • Weight gain.
  • Allergic skin reactions (rash, hives, sensitivity to sun rays).
  • Flu-like symptoms.
  • Anemia.
  • Liver dysfunction (jaundice, bile duct blockage, hepatitis).
  • Stomach discomfort. If severe hypoglycemia occurs, or if symptoms persist or worsen, medical attention should be sought immediately.

• Precautions

  • Hypoglycemia: K GLIM 1 TABLET can cause moderate to severe lowering of blood glucose levels. Patients should be educated on the signs of hypoglycemia and carry a fast-acting source of glucose.
  • Alcohol Consumption: Avoid alcohol as it can increase the risk of low blood sugar levels.
  • Photosensitivity: This medicine can make your skin sensitive to the sun; use sunscreen or wear protective clothing.
  • Kidney/Liver Disease: Use with caution in patients with kidney or liver problems, as dose adjustments may be necessary. It is not recommended for severe kidney or liver disease.
  • Cardiac Conditions: Use with caution in patients with cardiovascular diseases due to an increased risk of heart failure.
  • Pregnancy and Breastfeeding: Not recommended during pregnancy as it may harm the unborn baby. Consult a doctor if pregnant, planning pregnancy, or breastfeeding.
  • Type 1 Diabetes and Diabetic Ketoacidosis: K GLIM 1 TABLET is not for use in Type 1 Diabetes Mellitus or diabetic ketoacidosis.
  • G6PD Deficiency: Not recommended for individuals with Haemolytic Anaemia or G6PD deficiency.
  • Drug Interactions: Inform your doctor about all other medicines, supplements, or herbal products being taken, as interactions can occur with medications such as insulin, ACE inhibitors, corticosteroids, thiazides, thyroid hormones, and certain antifungals.
  • Driving and Operating Machinery: This medicine may decrease alertness due to potential fluctuations in blood sugar. Exercise caution when driving or operating machinery.

• Storage Store K GLIM 1 TABLET in a cool and dry place, away from direct sunlight. Keep it out of sight and reach of children. Typically, it should be stored at 10ºC to 25ºC or below 30ºC in its original packaging.

K GLIM 1 TABLET, manufactured by Blue Cross Laboratories Ltd., contains Glimepiride and is an oral anti-diabetic medicine primarily used to manage Type 2 Diabetes Mellitus in adults.

What is K GLIM 1 TABLET used for?

K GLIM 1 TABLET is used to lower high blood sugar levels in adults with Type 2 Diabetes Mellitus. It is typically prescribed when diet and exercise alone are not sufficient to control blood sugar. It can also be used in conjunction with other anti-diabetic medications or insulin to achieve better glycemic control and prevent complications such as kidney damage, blindness, and nerve problems.

How does K GLIM 1 TABLET work?

K GLIM 1 TABLET, containing Glimepiride, belongs to a class of medicines called sulfonylureas. It works by stimulating the beta cells in the pancreas to produce and release more insulin. Additionally, it increases the sensitivity of the body's tissues to insulin, helping the body utilize glucose more effectively and thereby lowering blood sugar levels.

What is the usual dosage for K GLIM 1 TABLET?

The usual starting dose of K GLIM 1 TABLET is typically 1 mg or 2 mg once daily, taken with breakfast or the first main meal of the day. The dosage may be gradually increased by your doctor, not exceeding 2 mg at 1- to 2-week intervals, based on your blood glucose levels. The maximum recommended dose is 8 mg once daily. It is crucial to take this medicine regularly at the same time each day as prescribed by your doctor.

What are the possible side effects of K GLIM 1 TABLET?

The most common side effect of K GLIM 1 TABLET is hypoglycemia (low blood sugar levels), which can manifest as sweating, dizziness, headache, shaking, increased hunger, and confusion. Other possible side effects include nausea, headache, dizziness, flu-like symptoms, allergic skin reactions (rash, itching, hives, sensitivity to sun), anemia, jaundice, and weight gain. If you experience symptoms of low blood sugar, it's advisable to carry a fast-acting source of glucose, like candy or fruit juice.

Is K GLIM 1 TABLET safe during pregnancy or breastfeeding?

K GLIM 1 TABLET is generally not recommended during pregnancy as it may be unsafe and could harm the unborn baby. Similarly, it is probably unsafe to use while breastfeeding, as it is not known if the medicine passes into breast milk and could potentially harm the baby. It is essential to consult your doctor if you are pregnant, planning to become pregnant, or breastfeeding to discuss the risks and benefits, and they may consider switching to insulin therapy.

Can K GLIM 1 TABLET be taken with other medications?

K GLIM 1 TABLET can interact with various medications. For example, insulin and ACE inhibitors (like enalapril or lisinopril) can increase the risk of low blood sugar when taken with K GLIM 1 TABLET. Corticosteroids, thiazide diuretics, and thyroid hormones (like levothyroxine) may reduce the sugar-lowering effectiveness of K GLIM 1 TABLET. Certain antibiotics, such as ciprofloxacin, and CYP2C9 inhibitors like fluconazole, may also potentiate the effects of glimepiride. Always inform your doctor about all medicines, supplements, and herbal remedies you are taking to avoid potential interactions.

What precautions should be taken while using K GLIM 1 TABLET?

Several precautions should be observed. K GLIM 1 TABLET can cause low blood sugar, especially in the elderly, malnourished individuals, or those with kidney and hormonal disorders. It is not recommended for individuals with Type 1 diabetes, diabetic ketoacidosis, or severe liver or kidney problems. Alcohol consumption should be avoided or limited as it can increase the risk of low blood sugar. The medicine can make your skin more sensitive to the sun, so using sunscreen or wearing protective clothing is advisable. Inform your doctor about any existing heart disease, thyroid conditions, or G6PD deficiency.

What happens if a dose of K GLIM 1 TABLET is missed?

If you miss a dose of K GLIM 1 TABLET, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to compensate for the missed one.

How should K GLIM 1 TABLET be stored?

K GLIM 1 TABLET should be stored in a cool, dry place, away from excessive heat and direct sunlight. The ideal storage temperature is generally below 30°C (or between 10°C to 25°C). Keep the medicine out of sight and reach of children. Ensure the lid is closed tightly after use to protect it from air and moisture.