Glevo 500 Mg Tablet (10 Tab)

GLEVO 500 MG TABLET (10 TAB) by GLENMARK PHARMACEUTICALS LTD.

Name:

• Brand Name: Glevo 500 MG Tablet
• Common Name: Levofloxacin (active ingredient)

Composition: Each tablet contains Levofloxacin 500 mg. Glevo 500 is a synthetic fluoroquinolone antibiotic. It works by inhibiting bacterial DNA gyrase and topoisomerase IV, enzymes critical for bacterial DNA replication and cell division, ultimately leading to bacterial cell death.

Uses: Glevo 500 MG Tablet is prescribed to treat a variety of bacterial infections. These include:

• Respiratory tract infections (e.g., pneumonia, bronchitis, sinusitis)
• Urinary tract infections (UTIs), including complicated and uncomplicated UTIs, cystitis, urethritis, and pyelonephritis
• Skin and soft tissue infections
• Kidney and prostate infections (e.g., prostatitis)
• Serious conditions such as inhalation anthrax and plague. It is important to note that Glevo 500 is effective only against bacterial infections and not against viral infections like the common cold or flu.

Dosage and Administration: Glevo 500 MG Tablet should be taken orally as directed by a healthcare professional. It is typically taken once daily, with or without food. Swallow the tablet whole with a glass of water; do not crush, chew, or split it. It is crucial to complete the full course of treatment, even if symptoms improve, to prevent the development of antibiotic resistance and ensure the infection is fully eradicated.

Side Effects: Common side effects may include:

• Nausea, vomiting, diarrhea, constipation
• Headache, dizziness
• Trouble sleeping (insomnia)
• Stomach pain, skin rash More serious, though less common, side effects can include tendon pain or rupture, symptoms of nerve damage (numbness, tingling, burning, weakness), and central nervous system effects such as seizures or confusion. Discontinue use and seek immediate medical attention if you experience a rash, itchy skin, swelling of the face or mouth, or difficulty breathing.

Precautions:

• Allergies: Do not take Glevo 500 if you are allergic to levofloxacin, other fluoroquinolone antibiotics, or any of its components.
• Medical Conditions: Use with caution and inform your doctor if you have a history of seizures/epilepsy, kidney or liver problems, irregular heartbeat (QT prolongation), low blood potassium levels, or myasthenia gravis, as this medicine may worsen muscle weakness.
• Drug Interactions: Avoid consuming dairy products (e.g., milk, yogurt) for at least 2 hours before or after taking Glevo 500. Inform your doctor about all other medications, supplements, and herbal products you are taking, as interactions can occur with antacids (magnesium/aluminum), sucralfate, iron supplements, NSAIDs, warfarin, and certain other drugs.
• Sunlight Exposure: Avoid prolonged exposure to direct sunlight or artificial UV light, as Glevo 500 can increase sensitivity to the sun.
• Pregnancy and Breastfeeding: Consult your doctor before using Glevo 500 if you are pregnant, planning to conceive, or breastfeeding, as it is generally not recommended during pregnancy and is excreted in human milk.
• Pediatric Use: Not recommended for children and adolescents under 18 years of age.

Storage: Store Glevo 500 MG Tablet in a cool, dry place, ideally at a temperature between 10°C to 25°C or below 30°C. Keep it away from direct sunlight, moisture, and out of the reach of children. Always check the expiry date before use.

GLEVO 500 MG TABLET is an antibiotic medicine containing Levofloxacin. It is used to treat various bacterial infections.

What is GLEVO 500 MG Tablet used for?

GLEVO 500 MG Tablet is used to treat a wide range of bacterial infections. These include infections of the urinary tract, skin and soft tissues, respiratory system (such as pneumonia, bronchitis, and sinusitis), kidneys, and prostate. It is also used for serious conditions like inhalation anthrax and plague. It is important to note that this medicine is only effective against bacterial infections, not viral infections like the common cold or flu.

How does GLEVO 500 MG Tablet work?

GLEVO 500 MG Tablet contains Levofloxacin, which is a fluoroquinolone antibiotic. It works by inhibiting crucial bacterial enzymes called DNA gyrase and Topoisomerase IV. These enzymes are essential for bacterial DNA replication, transcription, repair, and recombination. By blocking these processes, Levofloxacin disrupts the growth and division of bacterial cells, ultimately leading to their death and clearing the infection.

What is the usual dosage for GLEVO 500 MG Tablet?

The dosage of GLEVO 500 MG Tablet should be taken exactly as prescribed by your doctor. It is typically taken once a day, with or without food. The tablet should be swallowed whole with a glass of water and not crushed, chewed, or split. It is crucial to complete the full course of treatment, even if you start to feel better, to ensure the infection is fully eradicated and to prevent bacterial resistance.

What are the possible side effects of GLEVO 500 MG Tablet?

Common side effects of GLEVO 500 MG Tablet can include nausea, diarrhea, headache, dizziness, trouble sleeping (insomnia), indigestion, constipation, and stomach pain. More serious, but less common, side effects can involve tendon pain, tendonitis, or tendon rupture, nerve damage (symptoms like numbness, tingling, burning, or weakness), central nervous system effects (such as seizures, tremors, confusion, or hallucinations), skin rash, and fatigue. If you experience any severe or persistent side effects, you should consult your doctor immediately.

Is GLEVO 500 MG Tablet safe during pregnancy or breastfeeding?

Pregnancy: Caution is advised when taking GLEVO 500 MG Tablet during pregnancy. It is generally considered unsafe as there is definite evidence of risk to the developing baby, particularly to the joints of the fetus. Your doctor may only prescribe it in life-threatening situations where the benefits are considered to outweigh the risks.

Breastfeeding: GLEVO 500 MG Tablet is likely unsafe during breastfeeding. Limited data indicates that it may pass into breast milk and potentially harm the baby. It is crucial to discuss the potential risks and benefits with your doctor before starting this medication if you are breastfeeding.

Can GLEVO 500 MG Tablet be taken with other medications?

You should inform your doctor about all the medicines, supplements, or herbal products you are currently taking or plan to take to avoid potential interactions. Avoid taking antacids or dairy products (like milk or curd) for at least two hours before and after taking GLEVO 500 MG Tablet, as they can interfere with its absorption. Caution is advised with medications for heart problems, brain disorders, other antibiotics, blood thinners, painkillers, steroids, methotrexate, cimetidine, probenecid, and iron supplements. Iron supplements should also be taken at least two hours before or after GLEVO 500 MG Tablet.

What precautions should be taken while using GLEVO 500 MG Tablet?

It is essential to complete the entire prescribed course of GLEVO 500 MG Tablet, even if your symptoms improve, to prevent antibiotic resistance. Avoid consuming alcohol, as it may increase the risk of side effects like drowsiness, dizziness, and liver problems. Exercise caution if you have a history of liver or kidney impairment, heart problems (especially QT prolongation), tendon issues, muscle weakness (myasthenia gravis), or epilepsy/seizures. Avoid prolonged exposure to direct sunlight or artificial UV light, as this medicine can increase photosensitivity. Since it may cause dizziness or sleepiness, it is advisable not to drive or operate heavy machinery until you know how the medicine affects you. Do not take this medicine if you have a known allergy to Levofloxacin or other fluoroquinolone antibiotics. It is also generally not recommended for children and adolescents under 18 years of age.

What happens if a dose of GLEVO 500 MG Tablet is missed?

If you miss a dose of GLEVO 500 MG Tablet, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed one and continue with your regular dosing schedule. Do not take a double dose to make up for a missed dose, as this may increase the chances of side effects.

How should GLEVO 500 MG Tablet be stored?

GLEVO 500 MG Tablet should be stored in a cool and dry place, ideally at a temperature between 20°C to 25°C or below 30°C. Keep it away from direct sunlight and moisture. Ensure that the medicine is kept securely out of reach of children. Always check the expiry date on the package before using the medicine.