Ezuric 25 Mg Tablet (10 Tab)

EZURIC 25 MG TABLET (10 TAB) by ALKEM LABORATORIES LTD.

Name

• Brand Name: Ezuric 25 MG Tablet
• Common Name: Eplerenone (25 mg)

Composition

Ezuric 25 MG Tablet contains Eplerenone 25 mg as its active ingredient. Eplerenone is a selective aldosterone receptor antagonist, also classified as a potassium-sparing diuretic. It works by blocking the action of aldosterone, a natural substance that can increase blood pressure and fluid retention, and by helping the kidneys remove extra water and salt from the body.

Uses

Ezuric 25 MG Tablet is primarily used for:

• Managing mild to moderate high blood pressure (hypertension).
• Controlling heart failure, especially after a heart attack, in patients with left ventricular dysfunction and clinical symptoms of heart failure. It helps to improve heart function and reduce the risk of cardiovascular death and hospitalization.
• Reducing edema (swelling) caused by various conditions.

Dosage and Administration

The typical dosage of Ezuric 25 MG Tablet is once daily, or as instructed by a doctor. It can be taken with or without food, but it is recommended to take it in the same manner each time for maximum benefit. Taking it with food may help alleviate certain side effects, and taking it earlier in the day can prevent nighttime bathroom visits. The tablet should be swallowed whole with a glass of water and not crushed, chewed, or broken. It is crucial to adhere to the prescribed dosage and not discontinue the medication without consulting a doctor, even if symptoms improve.

Side Effects

Common side effects may include:

• Dizziness, headache, fatigue
• Nausea, diarrhea, abdominal pain
• Cough and flu-like symptoms
• Increased potassium levels (hyperkalemia)
• Sleeplessness, low blood pressure, vomiting
• Back pain, muscle cramps, weakness
• Increased creatinine levels Less common side effects can include low sodium levels, dehydration, elevated triglyceride levels, a fast heartbeat, inflammation of the gallbladder, and decreased blood pressure upon standing.

Precautions

• Kidney and Liver Conditions: Use with caution in patients with kidney or liver disease. It is contraindicated in severe liver or kidney disease and in individuals with high serum potassium levels or anuria.
• Hyperkalemia Risk: Ezuric can increase blood potassium levels. Patients should avoid potassium supplements and potassium-rich foods (e.g., bananas, broccoli) while on this medication. Regular monitoring of kidney function and potassium levels is essential.
• Pregnancy and Breastfeeding: Caution is advised during pregnancy, and it should only be used if clearly necessary. It is contraindicated for breastfeeding women.
• Alcohol: Limit alcohol consumption as it may increase drowsiness and other side effects.
• Driving and Machinery: Ezuric may cause dizziness or affect vision, so caution is advised when driving or operating machinery until the individual knows how the medicine affects them.
• Drug Interactions: Inform your doctor about all other medications, supplements, and herbal remedies being taken, as interactions can occur. Specific interactions include those with NSAIDs, ciclosporin, tacrolimus, trimethoprim, and warfarin.
• Diabetes: Ezuric-25 Tablet could impact blood sugar control, necessitating close monitoring of glucose levels.

Storage

Store Ezuric 25 MG Tablet at room temperature, ideally below 30°C, and in a tightly closed container. Protect the medicine from light and moisture. Always keep this medication out of sight and reach of children and pets. Ensure to use the tablet before its expiry date.

EZURIC 25 MG TABLET, manufactured by Alkem Laboratories Ltd., contains Eplerenone 25mg as its active ingredient. Eplerenone is a selective aldosterone receptor antagonist, also known as a potassium-sparing diuretic. It is primarily used to manage high blood pressure and heart failure.

Here are some frequently asked questions about EZURIC 25 MG TABLET:

What is EZURIC 25 MG TABLET used for?

EZURIC 25 MG TABLET is primarily used to treat high blood pressure (hypertension) and heart failure. It can also be used to improve heart function after a heart attack in patients with a weak left ventricle and symptoms of heart failure, and to reduce swelling (edema) caused by various conditions.

How does EZURIC 25 MG TABLET work?

EZURIC 25 MG TABLET contains Eplerenone, which is a potassium-sparing diuretic. It works by blocking the action of aldosterone, a natural hormone in the body that can increase blood pressure and cause fluid retention by increasing sodium and water reabsorption. By inhibiting aldosterone, Eplerenone helps the kidneys remove extra salt and water from the body without losing too much potassium, thereby lowering blood pressure and reducing fluid retention around the heart.

What is the usual dosage for EZURIC 25 MG TABLET?

The usual starting dose for EZURIC 25 MG TABLET for heart failure after a heart attack is typically 25 mg once a day, which may be increased to a maximum of 50 mg once daily within four weeks, as tolerated. For high blood pressure, the recommended starting dose is often 50 mg once daily, and if the response is inadequate, it may be increased to 50 mg twice daily. The dosage can vary based on your condition and response to medication, and it should always be followed as prescribed by your doctor.

What are the possible side effects of EZURIC 25 MG TABLET?

Common side effects may include dizziness, headache, fatigue, nausea, diarrhea, abdominal pain, cough, and flu-like symptoms. It can also increase potassium levels in the blood (hyperkalemia), which might lead to muscle weakness or an irregular heartbeat. If any side effects persist or worsen, you should consult your doctor.

Is EZURIC 25 MG TABLET safe during pregnancy or breastfeeding?

For pregnancy, EZURIC 25 MG TABLET should be used with caution and only if clearly needed, and if the potential benefits outweigh the risks. There is limited information available regarding its safety during breastfeeding; therefore, it's advised to consult your doctor if you are pregnant, planning to become pregnant, or breastfeeding. Small amounts of Eplerenone may pass into breast milk, and careful infant monitoring is recommended if used during breastfeeding.

Can EZURIC 25 MG TABLET be taken with other medications?

EZURIC 25 MG TABLET can interact with several medications. Concomitant use with strong CYP3A4 inhibitors (like certain antifungals such as ketoconazole and itraconazole, or some antivirals) is contraindicated as it can increase Eplerenone levels. Other medications that can interact include certain blood pressure-lowering medicines (like ACE inhibitors or ARBs, which can increase the risk of high potassium levels), NSAIDs (which may reduce its effectiveness and increase the risk of high potassium), other potassium-sparing diuretics, and potassium supplements. Always inform your doctor about all other medications, supplements, and herbal remedies you are taking to prevent potential interactions.

What precautions should be taken while taking EZURIC 25 MG TABLET?

It is crucial to have your blood potassium levels monitored regularly, especially when starting treatment or after a dose adjustment, as Eplerenone can increase potassium levels. Caution is advised for patients with kidney or liver problems, diabetes (especially with protein in the urine), or Addison's disease. Avoid potassium supplements and salt substitutes containing potassium unless advised by your doctor. Alcohol consumption should be limited or avoided as it can increase certain side effects like dizziness. This medicine may cause dizziness, so avoid driving or operating heavy machinery until you know how it affects you.

What happens if a dose of EZURIC 25 MG TABLET is missed?

If you miss a dose of EZURIC 25 MG TABLET, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.

How should EZURIC 25 MG TABLET be stored?

EZURIC 25 MG TABLET should be stored at room temperature, ideally below 30°C (86°F), in a tightly closed container. Keep it away from light and moisture, and out of reach of children and pets. Ensure to use it before its expiry date.