Glimer 2 Mg Tablet (15 Tab)

GLIMER 2 MG TABLET (15 TAB) by ABBOTT HEALTHCARE PVT. LTD.

Name

• Brand Name: Glimer 2 MG Tablet
• Common Name: Glimepiride

Composition

• Each tablet contains Glimepiride 2 mg as the active ingredient.

Uses Glimer 2 MG Tablet is prescribed for the management of Type 2 Diabetes Mellitus in adults. It works by stimulating insulin secretion and improving insulin sensitivity to help control blood sugar levels. This medication also aids in preventing serious long-term complications associated with diabetes, such as kidney damage, blindness, nerve problems, limb amputations, and cardiovascular issues.

Dosage and Administration

• Glimer 2 MG Tablet is typically taken once daily, either just before or with the first main meal of the day (usually breakfast).
• The recommended starting dose is 1 mg or 2 mg once daily. For patients at higher risk of low blood sugar (e.g., elderly or those with renal impairment), a starting dose of 1 mg once daily may be given.
• The usual maintenance dose ranges from 1–4 mg once daily, with a maximum recommended dose of 8 mg once daily.
• Dosage adjustments are determined by a healthcare professional based on individual blood glucose levels, typically not exceeding 2 mg at 1- to 2-week intervals.
• Tablets should be swallowed whole with water; they should not be split, crushed, chewed, or dissolved.
• It is crucial to take this medicine regularly as prescribed and not to stop it without consulting a doctor, even if blood sugar levels appear controlled.

Side Effects

• Common Side Effects: Low blood sugar (hypoglycemia), nausea, dizziness, headache, and weight gain. Increased skin sensitivity to sunlight may also occur.
• Symptoms of Hypoglycemia: Sweating, feeling hungry, trembling or shaking, confusion, problems concentrating, weakness, rapid heartbeat, drowsiness, and in severe cases, seizures or loss of consciousness.
• Serious Side Effects: Allergic reactions (e.g., skin rash, hives), liver dysfunction (e.g., jaundice, hepatitis), and seizures.

Precautions

• Contraindications: Glimer 2 MG Tablet should not be used in patients with Type 1 Diabetes Mellitus, diabetic ketoacidosis, severe kidney or liver disease, G6PD-deficiency, or a known allergy to glimepiride, sulfonylureas, or sulfonamides.
• Pregnancy and Breastfeeding: This medicine is generally not recommended during pregnancy or breastfeeding. It is important to discuss with a doctor if pregnant, planning pregnancy, or breastfeeding.
• Alcohol Consumption: Limit or avoid alcohol intake as it can interfere with diabetes control and increase the risk of low blood sugar.
• Liver and Kidney Impairment: Use with caution in patients with liver or kidney problems; dose adjustments may be necessary. It is not recommended in severe cases.
• Drug Interactions:
  • May cause a significant drop in blood glucose levels when taken with other antidiabetic medicines (e.g., metformin, insulin), fluconazole, aspirin, warfarin, ramipril, lisinopril, or allopurinol.
  • May increase blood glucose levels when taken with oestrogens, progestogens, diuretics, levothyroxine, rifampicin, glucocorticoids, or chlorpromazine.
• Driving and Operating Machinery: Due to the risk of hypoglycemia, which can cause dizziness and reduced alertness, caution is advised when driving or operating machinery.
• Photosensitivity: This medicine can make the skin more sensitive to sunlight. Patients should use sunscreen or wear protective clothing when outdoors.
• Stressful Conditions: Discontinue use and consult a doctor if experiencing stressful conditions such as fever, trauma, surgery, or accidents, as its effectiveness in controlling blood sugar may be reduced.

Storage

• Store Glimer 2 MG Tablet at room temperature, ideally between 15-25 °C or below 30 °C.
• Keep the medicine away from direct heat, light, and moisture.
• Ensure it is kept out of the reach of children.
• Always check and use the medicine before its expiry date.

GLIMER 2 MG TABLET contains glimepiride as its active ingredient. This medication is primarily used to manage type 2 diabetes by helping to lower high blood sugar levels. It works best when used in conjunction with a healthy diet and regular exercise.

What is GLIMER 2 MG TABLET used for?

GLIMER 2 MG TABLET is used to control high blood sugar levels in adults with type 2 diabetes mellitus. It is prescribed when diet and exercise alone are not sufficient to manage blood glucose. By lowering blood sugar, it helps prevent serious long-term complications of diabetes, such as kidney damage, blindness, nerve problems, and cardiovascular issues. It is not used for type 1 diabetes or diabetic ketoacidosis.

How does GLIMER 2 MG TABLET work?

GLIMER 2 MG TABLET belongs to a class of medications called sulfonylureas. It works primarily by stimulating the beta cells in the pancreas to release more insulin. Additionally, it helps to increase the sensitivity of your body's tissues to insulin, allowing cells to more effectively take up sugar (glucose) from the bloodstream and use it for energy.

What is the usual dosage for GLIMER 2 MG TABLET?

The usual starting dose for glimepiride is 1 mg or 2 mg, taken once daily with breakfast or the first main meal of the day. Your doctor may gradually increase the dose by 1 mg or 2 mg increments every 1 to 2 weeks, based on your blood sugar levels. The maximum recommended dose is typically 8 mg once daily. It is important to take this medication with food.

What are the possible side effects of GLIMER 2 MG TABLET?

Common side effects can include low blood sugar (hypoglycemia), headache, nausea, dizziness, weakness, indigestion, diarrhea, and weight gain.

Serious but rare side effects may include severe allergic reactions (such as skin rash, hives, swelling of the face/throat, or trouble breathing), liver problems (like jaundice), and blood disorders. You should contact your doctor if you experience any severe or persistent side effects.

Is GLIMER 2 MG TABLET safe during pregnancy or breastfeeding?

Pregnancy: GLIMER 2 MG TABLET (glimepiride) is generally not recommended during pregnancy. Animal studies have shown adverse effects on the fetus, and there aren't enough studies in humans to confirm its safety. Your doctor will likely recommend safer alternatives, such as insulin or metformin, if you are pregnant or planning to become pregnant.

Breastfeeding: It is usually not recommended to take glimepiride while breastfeeding. It is not known if glimepiride passes into breast milk, but if it does, it could potentially cause low blood sugar in a breastfed infant. Your doctor will help you decide on the best course of action for you and your baby.

Can GLIMER 2 MG TABLET be taken with other medications?

GLIMER 2 MG TABLET can interact with many other medications, which can either increase or decrease its blood sugar-lowering effect. It is crucial to inform your doctor about all medications, supplements, and herbal remedies you are taking.

Some medications that may increase the effect of glimepiride (and thus lower blood sugar further) include certain antibiotics (e.g., quinolones, chloramphenicol), antifungals, ACE inhibitors, aspirin, and some NSAIDs.

Conversely, some medications that may decrease its effect (and raise blood sugar) include thiazide diuretics, corticosteroids, estrogens, and certain thyroid medications. If taking colesevelam, glimepiride should be taken at least 4 hours prior.

Avoid consuming alcohol while taking glimepiride, as it can significantly affect your blood sugar levels.

What precautions should be taken while on GLIMER 2 MG TABLET?

It is very important to regularly monitor your blood sugar levels and follow your doctor's instructions regarding diet and exercise. You should be aware of the symptoms of low blood sugar (hypoglycemia), such as hunger, trembling, sweating, confusion, and dizziness, and always carry a quick source of sugar (like glucose tablets or juice) to treat it.

Inform your doctor about any existing medical conditions, especially kidney or liver disease, heart disease, thyroid disorders, or a deficiency of glucose-6-phosphate dehydrogenase (G6PD). This medication can also make your skin more sensitive to sunlight, so it's advisable to wear protective clothing and use sunscreen. Do not skip meals while on this medication.

What happens if a dose is missed?

If you miss a dose of GLIMER 2 MG TABLET, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you frequently miss doses, consider setting an alarm or asking your pharmacist for tips on remembering your medication.

How should GLIMER 2 MG TABLET be stored?

Store GLIMER 2 MG TABLET at room temperature, typically between 20°C and 25°C (68°F and 77°F), and keep it away from light and moisture. Do not freeze the medication. Ensure it is kept out of reach of children and pets.