Bigomet M Tab

BIGOMET M TAB

BIGOMET M TAB, manufactured by Aristo Pharmaceuticals Pvt Ltd, is a combination medication primarily used in the management of Type 2 Diabetes Mellitus. It is often prescribed for adults to help control blood sugar levels and reduce the risk of diabetes-related complications. The "SR" in some product names, like Bigomet M Tablet SR, indicates a sustained-release formulation.

Composition

BIGOMET M TAB contains two active ingredients:

• Metformin (500 MG)
• Methylcobalamin (750 MCG)

Metformin, a biguanide, works by decreasing glucose production in the liver, reducing intestinal glucose absorption, and enhancing insulin sensitivity to improve glucose uptake and utilization by the body. Methylcobalamin, a form of Vitamin B12, helps in the synthesis of the myelin sheath that protects nerves, aids in regenerating injured nerves, and plays a role in red blood cell formation and nervous system function. It is included to address potential vitamin B12 deficiency that Metformin may cause.

Uses

BIGOMET M TAB is prescribed for:

• Management of Type 2 Diabetes Mellitus in adults.
• It helps to control high blood sugar levels and minimize the risk of serious complications such as kidney damage, blindness, nerve problems, and limb loss.
• It may also be used to treat Polycystic Ovary Syndrome (PCOS).

Dosage and Administration

BIGOMET M TAB should be taken in the dose and duration advised by your physician.

• It should be taken with food, preferably at the same time each day.
• Swallow the tablet whole with a glass of water; do not crush or chew it.
• If a dose is missed, take it as soon as possible. However, if it's almost time for the next dose, skip the missed dose and return to the regular schedule. Do not double the dose.

Side Effects

Common side effects may include:

• Nausea, vomiting
• Diarrhea
• Abdominal pain, stomach pain
• Loss of appetite
• Changes in taste
• Headache, dizziness, sweating

Serious side effects, though rare, include:

• Lactic acidosis: Symptoms can include vomiting, abdominal pain, muscle cramps, severe tiredness, difficulty breathing, reduced body temperature, and a slow heartbeat. This is a life-threatening condition requiring immediate medical attention.

Precautions

• Kidney and Liver Function: Not recommended for use in severe kidney dysfunction or severe liver disease. Regular monitoring of kidney function is advisable.
• Heart Conditions: Use with caution in patients with heart problems like acute heart failure or a recent history of heart attack, as it may increase the risk of heart failure.
• Pregnancy and Breastfeeding: Not recommended for use during pregnancy or in breastfeeding women, as it may pass into breast milk. Consult your doctor.
• Alcohol Consumption: Avoid excessive alcohol intake as it increases the risk of lactic acidosis.
• Dehydration: Discontinue use and seek medical attention if dehydration occurs due to severe vomiting, diarrhea, heat exposure, or fever.
• Drug Interactions: Inform your doctor about all other medicines you are taking, especially other antidiabetic medicines (sulfonylureas, insulin, meglitinides), diuretics, beta-2 agonists, corticosteroids, verapamil, rifampicin, cimetidine, and dolutegravir.
• Other Conditions: Not recommended for Type 1 diabetes, diabetic ketoacidosis, or conditions causing severe infections or circulation problems.

Storage

Store in a cool and dry place, away from sunlight. Keep out of sight and reach of children. Store below 25°C or 30°C.

Here are some frequently asked questions about BIGOMET M TAB:

What is BIGOMET M TAB used for?

BIGOMET M TAB is a combination medication primarily used for the management of Type 2 Diabetes Mellitus in adults. It helps to control high blood sugar levels. Additionally, it may be prescribed for patients with diabetes who are at risk of or experiencing vitamin B12 deficiency-related nerve problems, as it contains methylcobalamin to help with nerve health. Some sources also indicate its use in treating Polycystic Ovary Syndrome (PCOS).

How does BIGOMET M TAB work?

BIGOMET M TAB contains two active ingredients: Metformin and Methylcobalamin. Metformin, an antidiabetic agent, works by decreasing the production of glucose in the liver, reducing the absorption of glucose from the intestines, and increasing the body's sensitivity to insulin. This allows for better glucose uptake and utilization by the body, effectively controlling blood sugar levels. Methylcobalamin, a form of vitamin B12, helps in the synthesis of the myelin sheath (a protective covering over nerves) and aids in regenerating injured nerves. It also plays a role in red blood cell formation and the proper functioning of the brain and nervous system, addressing potential vitamin B12 deficiencies that can occur with metformin use.

What is the usual dosage for BIGOMET M TAB?

The dosage of BIGOMET M TAB should always be as advised by your doctor, who will determine it based on your age, body weight, and medical condition. It is typically taken orally, preferably with meals, and at the same time each day to maintain consistent blood sugar control. A common strength mentioned is Metformin 500 mg and Methylcobalamin 750 mcg per tablet, with a frequency of twice daily for some formulations. Do not chew, crush, or break the tablet.

What are the possible side effects of BIGOMET M TAB?

Common side effects of BIGOMET M TAB may include nausea, vomiting, diarrhea, abdominal pain, loss of appetite, changes in taste, headache, and stomach upset. These are usually temporary and tend to subside as your body adjusts to the medication. A rare but serious side effect is lactic acidosis, characterized by symptoms such as severe tiredness, difficulty breathing, abdominal pain with muscle cramps, and reduced body temperature and heartbeat. Seek immediate medical attention if you experience these symptoms.

Is BIGOMET M TAB safe during pregnancy or breastfeeding?

BIGOMET M TAB is generally not recommended for use during pregnancy. It is crucial to inform your doctor if you are pregnant or planning to become pregnant before taking this medication. For breastfeeding women, BIGOMET M TAB is generally not recommended as it may pass into breast milk. However, some sources state it is "safe if prescribed," so consultation with your doctor is essential to weigh the benefits against potential risks.

Can BIGOMET M TAB be taken with other medications?

It is important to inform your doctor about all other medications you are taking, including over-the-counter drugs, supplements, and herbal remedies, as BIGOMET M TAB can interact with several medicines. Some medications that may interact include other antidiabetic agents (like sulfonylureas, insulin), diuretics (e.g., chlorothiazide), corticosteroids (e.g., dexamethasone), beta-2 agonists (e.g., salbutamol), verapamil, rifampicin, cimetidine, and certain medications for pain and inflammation (NSAIDs). These interactions can affect blood glucose control or increase the risk of side effects like lactic acidosis.

What precautions should be taken while taking BIGOMET M TAB?

Before taking BIGOMET M TAB, inform your doctor if you have kidney, liver, or heart problems, as the medication is not recommended for individuals with severely reduced kidney function, liver disease, acute heart failure, or a recent history of heart attack. Avoid excessive alcohol consumption, as it can significantly increase the risk of lactic acidosis. Your doctor will likely monitor your kidney function through blood tests before and during treatment. In cases of dehydration due to severe diarrhea, vomiting, heat exposure, or fever, you should discontinue the medication and seek medical attention immediately.

What happens if a dose of BIGOMET M TAB is missed?

If you miss a dose of BIGOMET M TAB, take it as soon as you remember, preferably with food. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to compensate for the missed one.

How should BIGOMET M TAB be stored?

BIGOMET M TAB should be stored in a cool and dry place, away from direct sunlight, and below 30°C. Keep the medicine out of the sight and reach of children.