Martifur 100

MARTIFUR 100 MR Tablet

MARTIFUR 100 MR Tablet, manufactured by Walter Bushnell, is an antibiotic primarily used for the treatment and prevention of bacterial infections of the urinary tract.

• Name:

  • Common Name: Nitrofurantoin
  • Brand Name: MARTIFUR 100 MR, MARTIFUR 100mg Tablet

• Composition:

  • Active Ingredients: Each tablet contains Nitrofurantoin 100 mg.

• Uses: MARTIFUR 100 MR Tablet is prescribed for the management of bacterial infections affecting the urinary system. This includes:

  • Urinary Tract Infections (UTIs)
  • Bladder infections (Cystitis)
  • Kidney infections It works by killing susceptible bacteria like Escherichia coli, enterococci, staphylococci, Citrobacter, Klebsiella, and Enterobacter that cause these infections. It is also used for the prevention of recurring UTIs and in specific scenarios such as prior to certain surgical procedures.

• Dosage and Administration:

  • MARTIFUR 100 MR Tablet should be taken as advised by a doctor.
  • It is typically taken orally with food or milk to enhance absorption and reduce the risk of stomach upset.
  • The tablet should be swallowed whole with a glass of water; avoid crushing, breaking, or chewing it.
  • It is crucial to complete the full prescribed course of treatment, even if symptoms improve earlier, to ensure the infection is fully eradicated and to prevent recurrence or antibiotic resistance.
  • Dosage frequency can vary, but commonly includes 2 to 4 times daily, with a usual course duration of 7 days, as directed by the doctor.

• Side Effects: Common side effects may include:

  • Nausea
  • Vomiting
  • Diarrhea
  • Loss of appetite
  • Headache
  • Flatulence
  • Dizziness or sleepiness
  • Urine discoloration (dark yellow or brown, which is normal and harmless)

  Serious, though rare, side effects can include:

  • Lung inflammation (especially with prolonged use)
  • Nerve damage (peripheral neuropathy), indicated by pain and numbness in hands and feet
  • Damage to red blood cells (hemolysis)
  • Allergic reactions

• Precautions:

  • Inform your doctor about any pre-existing conditions or other medications being taken.
  • Caution is advised in patients with liver disease, lung disease, kidney problems (especially creatinine clearance < 40 mL/minute), anemia, diabetes, or vitamin B deficiency.
  • Not recommended for infants below 3 months of age due to the risk of hemolytic anemia.
  • Use with caution in older patients, who may be more susceptible to side effects.
  • Avoid taking antacids containing magnesium trisilicate, as they can interfere with absorption.
  • Pregnant women should use with caution and only if prescribed by a doctor, avoiding use during labor and childbirth.
  • Caution is advised for breastfeeding women, and consultation with a doctor is recommended.
  • May cause dizziness or drowsiness; avoid driving or operating machinery if these symptoms occur.
  • Regular lung and liver function tests may be required during treatment.
  • Can interfere with urine tests for sugar, potentially yielding false positive results.
  • Avoid alcohol consumption as it may increase the risk of side effects.

• Storage:

  • Store in a cool and dry place.
  • Protect from heat, direct light, and moisture.
  • Keep out of sight and reach of children.
  • Typically stored at room temperature, generally below 25°C or 30°C.

Here are frequently asked questions about Martifur 100 by Walter Bushnell:

What is Martifur 100 used for?

Martifur 100 is an antibiotic primarily used to treat and prevent bacterial infections of the urinary tract (UTIs), including infections of the bladder, kidneys, and urethra. It helps reduce symptoms such as pain, burning sensation, and frequent urination associated with UTIs.

How does Martifur 100 work?

Martifur 100 contains Nitrofurantoin, which works by killing the bacteria responsible for urinary tract infections. It achieves this by entering the bacterial cells and disrupting the production of their genetic material, thereby interfering with their growth and reproduction.

What is the usual dosage for Martifur 100?

For acute uncomplicated urinary tract infections, the typical adult dosage is 50-100 mg four times daily for 7 days, or for 3 days after obtaining sterile urine. For prophylaxis (prevention) of uncomplicated UTIs, a dose of 50-100 mg at bedtime for up to 12 months may be prescribed. It is important to take Martifur 100 with food or milk to increase absorption and minimize stomach upset. Always follow your doctor's prescribed dosage and complete the full course of treatment.

What are the possible side effects of Martifur 100?

Common side effects can include nausea, vomiting, diarrhea, dizziness, drowsiness, loss of appetite, and headaches. These side effects are usually temporary and may subside as your body adjusts to the medication. Martifur 100 may also cause your urine to turn dark yellow or brown, which is a normal and harmless effect. More serious but rare side effects can include lung inflammation, liver damage, nerve damage (peripheral neuropathy), and damage to red blood cells. If you experience persistent or severe side effects, consult your doctor.

Is Martifur 100 safe during pregnancy or breastfeeding?

Martifur 100 should generally be used with caution during pregnancy and only if absolutely necessary, as advised by your doctor. It is contraindicated during pregnancy at term (38-42 weeks), during labor, and delivery due to potential harm to the baby. For breastfeeding mothers, Martifur 100 is generally not recommended as it is excreted in breast milk and may be harmful to the infant. Your doctor will weigh the benefits and risks if you are breastfeeding.

Can Martifur 100 be taken with other medications?

Martifur 100 can interact with certain medications. Antacids, particularly those containing magnesium hydroxide or aluminum hydroxide, may reduce its effectiveness by decreasing absorption. Medicines like probenecid and sulfinpyrazone, used for gout, can decrease the excretion of nitrofurantoin, potentially leading to increased levels in the body and a higher risk of toxicity. It may also antagonize the effects of norfloxacin. Always inform your doctor about all medicines, supplements, and herbal products you are currently taking.

What precautions should be taken while taking Martifur 100?

Exercise caution if you have pre-existing conditions such as lung or liver disease, anemia, diabetes, severe weakness, electrolyte imbalance, G6PD deficiency, or vitamin B deficiency. It should be used cautiously in elderly patients, especially those with kidney impairment. Martifur 100 is contraindicated in infants under three months of age due to the risk of hemolytic anemia. Avoid consuming alcohol while taking this medicine as it may increase the risk of side effects. Since it can cause dizziness or drowsiness, avoid driving or operating heavy machinery until you know how the medicine affects you. It is crucial to complete the entire prescribed course of treatment, even if you feel better, to prevent the infection from returning or worsening.

What happens if a dose of Martifur 100 is missed?

If you forget to take a dose, take it as soon as you remember. However, if it's almost time for your next scheduled dose, skip the missed one and continue with your regular dosing routine. Do not take a double dose to make up for the missed one.

How should Martifur 100 be stored?

Martifur 100 should be stored at room temperature, away from direct sunlight and moisture. Keep it out of reach of children and pets. Do not freeze the drug unless the package insert specifically requires it.