Ilosure 6

ILOSURE 6mg Tablet is a medication manufactured by Sun Pharmaceutical Industries Ltd., primarily used in the management of certain mental health conditions.

Name

• Brand Name: ILOSURE 6mg Tablet
• Common Name: Iloperidone (as 6mg strength)

Composition

ILOSURE 6mg Tablet contains Iloperidone (6mg) as its active ingredient. Iloperidone belongs to a class of medicines known as atypical antipsychotics.

Uses

ILOSURE 6mg Tablet is prescribed for adults to manage:

• Schizophrenia: A serious mental disorder affecting a person's ability to think, feel, or behave clearly, helping to reduce hallucinations, delusions, and disordered thinking.
• Mania: Characterized by an unusually elevated or irritable mood, excessive energy, and impulsive behavior.
• It may also be used in the treatment of depression and bipolar disorders.

Dosage and Administration

Take ILOSURE 6mg Tablet strictly as advised by your physician. It should be swallowed whole with a glass of water, and should not be crushed or chewed. It can be taken with or without food, preferably at the same time each day to maintain a consistent level in the body. The typical adult dosage for schizophrenia can start at 1 mg twice daily, with a maximum dose of 12 mg twice daily, depending on individual response and medical condition. Do not stop taking the medicine abruptly without consulting your doctor.

Side Effects

Common side effects may include:

• Dizziness, fatigue, drowsiness, and sleepiness.
• Nasal congestion (stuffy nose) and dry mouth.
• Low blood pressure, especially orthostatic hypotension (a sudden drop in blood pressure upon standing), irregular heartbeat (tachycardia).
• Weight gain.
• Arthralgia (joint pain), muscle spasms, blurred vision, nausea, diarrhea, and rash.

Serious side effects that require immediate medical attention include signs of Neuroleptic Malignant Syndrome (very high fever, irregular heartbeat, muscle rigidity) or Tardive Dyskinesia (involuntary movements like jaw swinging, repetitive chewing).

Precautions

• Contraindications: Not recommended for patients with known hypersensitivity to Iloperidone, a history of significant cardiovascular disease (such as QT prolongation, recent acute myocardial infarction, uncompensated heart failure, cardiac arrhythmia), or severe hepatic impairment.
• Specific Populations: Not recommended for children and adolescents below 18 years. Use with caution in elderly patients, especially those with dementia-related psychosis.
• Pregnancy and Breastfeeding: Use with caution during pregnancy only if clearly necessary, as it may cause extrapyramidal and/or withdrawal symptoms in neonates. Not recommended for use in breastfeeding women.
• Other Warnings: Avoid alcohol consumption as it can intensify dizziness and drowsiness. Do not drive or operate machinery until you know how the medicine affects you, as it can impair judgment and motor skills. Caution is advised for patients with a history of seizures, low white blood cell count, suicidal thoughts, kidney problems, and mild to moderate liver problems. This medicine may cause an increase in weight, blood sugar, cholesterol, and triglycerides.

Storage

Store ILOSURE 6mg Tablet at room temperature (25°C). Keep it in a cool, dry place away from sunlight, and protect it from moisture and light. Keep out of sight and reach of children.

ILOSURE 6 mg Tablet, manufactured by SUN PHARMA LABORATORIES LTD., contains Iloperidone, an atypical antipsychotic medication primarily used to manage schizophrenia and sometimes mania.

What is ILOSURE 6 mg Tablet used for?

ILOSURE 6 mg Tablet is primarily used in adults to treat schizophrenia, a serious mental disorder that affects a person's ability to think, feel, and behave clearly, often involving hallucinations and delusions. It may also be used to manage mania, a condition characterized by an unusually elevated or irritable mood, hyperactivity, and impaired judgment, and can assist in treating bipolar disorders.

How does ILOSURE 6 mg Tablet work?

ILOSURE 6 mg Tablet works as an atypical antipsychotic by rebalancing certain chemical messengers in the brain, specifically dopamine D2 receptors and serotonin type 2 (5-HT2) receptors. This modulation helps to stabilize brain activity, improving thoughts, feelings, and behavior, and reducing symptoms like hallucinations, delusions, and disorganized thinking.

What is the usual dosage for ILOSURE 6 mg Tablet?

The dosage of ILOSURE 6 mg Tablet is determined by your physician based on your age, body weight, and disease condition. It should be taken exactly as advised by your doctor, usually swallowed whole with a glass of water, and can be taken with or without food, ideally at the same time each day to maintain consistent medication levels. For schizophrenia, an adult dosage might start at 1 mg twice daily, with a maximum dose of 12 mg twice daily. Do not crush or chew the tablet.

What are the possible side effects of ILOSURE 6 mg Tablet?

Common side effects of ILOSURE 6 mg Tablet include dizziness, fatigue, dry mouth, nasal congestion, low blood pressure (especially when standing up quickly, known as orthostatic hypotension), drowsiness, fast heart rate (tachycardia), and weight gain. Some individuals may also experience joint pain (arthralgia), muscle stiffness, blurred vision, nausea, diarrhea, abdominal discomfort, or rash. Serious but rare side effects can include neuroleptic malignant syndrome (high fever, irregular heartbeat, muscle rigidity) and tardive dyskinesia (involuntary movements).

Is ILOSURE 6 mg Tablet safe during pregnancy or breastfeeding?

ILOSURE 6 mg Tablet should be used with caution during pregnancy and only if clearly necessary, as it may cause extrapyramidal and/or withdrawal symptoms in neonates, particularly when taken in the third trimester. It is generally not recommended for use in breastfeeding women, as limited human data suggests the drug may pass into breast milk and potentially harm the baby. Always consult your doctor if you are pregnant, planning pregnancy, or breastfeeding.

Can ILOSURE 6 mg Tablet be taken with other medications?

Before taking ILOSURE 6 mg Tablet, inform your doctor about all other medications, herbal supplements, and vitamins you are taking, as drug interactions can occur. Specific medications that may interact include fluoxetine, paroxetine (for depression), ketoconazole (for fungal infections), dextromethorphan (for cold and cough), midazolam (to induce sleep), and medicines that prolong the QT interval (e.g., quinidine, amiodarone). Taking it with alcohol is not recommended as it can intensify side effects like dizziness and drowsiness.

What precautions should be taken when using ILOSURE 6 mg Tablet?

Several precautions should be observed. Do not stop taking the medicine suddenly without consulting your doctor, as it can worsen symptoms. Exercise caution if you have a history of seizures, low white blood cell count, suicidal thoughts, kidney or liver problems, or heart conditions (such as QT prolongation, heart failure). The medicine is not recommended for children and adolescents under 18 or for elderly patients with dementia-related psychosis. It can cause dizziness and sleepiness, so avoid driving or operating heavy machinery until you understand how it affects you. Rise slowly from sitting or lying positions to avoid sudden drops in blood pressure. It may also cause an increase in weight, blood sugar, cholesterol, and triglycerides, so maintaining a healthy lifestyle with diet and exercise is advised.

What happens if a dose of ILOSURE 6 mg Tablet is missed?

If you miss a dose of ILOSURE 6 mg Tablet, take it as soon as you remember. However, if it is close to the time for your next scheduled dose (e.g., less than 6 hours away), skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to compensate for a missed one.

How should ILOSURE 6 mg Tablet be stored?

ILOSURE 6 mg Tablet should be stored at room temperature, typically between 10°C to 25°C or below 30°C. It should be kept in a cool, dry place, away from sunlight, moisture, and out of the sight and reach of children.