Diof Ds Susp

DIOF DS Suspension

DIOF DS Suspension is an antibiotic medication manufactured by ZUVENTUS HEALTHCARE LTD., used to treat a wide range of bacterial and parasitic infections.

• Name:

  • Brand Name: DIOF DS Suspension
  • Common Name: Ofloxacin & Metronidazole Suspension

• Composition: Each 5 ml of DIOF DS Suspension contains:

  • Ofloxacin IP 100 mg
  • Metronidazole Benzoate IP equivalent to Metronidazole 200 mg Ofloxacin is a fluoroquinolone antibiotic, and Metronidazole is a nitroimidazole antimicrobial. They work by damaging the DNA of infection-causing bacteria and parasites, preventing their growth and leading to their death.

• Uses: DIOF DS Suspension is prescribed for various bacterial and parasitic infections, including:

  • Bacterial infections of the lungs, skin, prostate, urinary tract, gastrointestinal tract, teeth, and genital tract.
  • Diarrhea due to mixed bacterial and parasitic infections.
  • Amoebic dysentery.
  • Pneumonia, tooth abscess, gum infection.
  • Uncomplicated skin infections, pelvic inflammatory disease, uncomplicated gonorrhea.
  • Chronic bacterial prostatitis, typhoid fever, and complicated UTIs.

• Dosage and Administration: DIOF DS Suspension is for oral administration. It is typically taken twice a day, usually once in the morning and once in the evening. It can be taken with or without food, but if stomach upset occurs, taking it with food is advised. Shake the suspension well before use. The exact dose and duration of treatment should be determined by a physician based on the patient's medical condition, age, body weight, and the type and severity of the infection. It is important to complete the full course of treatment as prescribed, even if symptoms improve, to prevent recurrence of the infection. If a dose is vomited within 30 minutes, it may be repeated, but never double the next scheduled dose.

• Side Effects: Common side effects may include:

  • Nausea, vomiting, stomach upset, abdominal pain.
  • Loss of appetite, dry mouth, metallic taste.
  • Headache, dizziness, drowsiness, confusion.
  • Mild skin rash, insomnia, urine discoloration. More serious, though rare, side effects can include severe allergic reactions (swelling, difficulty breathing, rash), tendinitis, or tendon rupture. Seek immediate medical attention if severe side effects occur.

• Precautions:

  • Allergies: Contraindicated in patients with hypersensitivity to ofloxacin, metronidazole, or other related antibacterial/anti-amoebic agents.
  • Medical Conditions: Use with caution in patients with a history of liver disease, kidney disease, seizure disorders (epilepsy), low blood white cells (leukopenia), gastrointestinal diseases (like Crohn's disease), other neurological disorders, or myasthenia gravis. Dose adjustments may be necessary for those with severe liver or kidney impairment.
  • Pregnancy & Breastfeeding: Not generally recommended during pregnancy, especially in the first trimester, or while breastfeeding. Consult a doctor to assess potential risks and benefits.
  • Alcohol: Avoid alcohol consumption during treatment as it may increase the risk of side effects such as dizziness and drowsiness.
  • Drug-Food Interactions: Avoid dairy products, antacids, or supplements containing calcium, magnesium, or iron within 2 hours of taking DIOF DS Suspension, as they can interfere with its absorption.
  • Sunlight Exposure: Avoid prolonged exposure to strong sunlight and UV light due to increased photosensitivity.
  • Driving & Machinery: Patients should avoid driving or operating heavy machinery if they experience dizziness, confusion, or drowsiness.
  • Children & Elderly: Should be used in children only under medical supervision. Special caution is advised for elderly patients due to an increased risk of tendon disorders.

• Storage: Store DIOF DS Suspension below 25°C or 30°C in a cool, dry place. Protect from light and moisture. Do not freeze. Keep out of sight and reach of children.

DIOF DS SUSP, manufactured by Zuventus Healthcare Ltd., is a combination antibiotic suspension containing Ofloxacin and Metronidazole. It is primarily used to treat various bacterial and parasitic infections.

What is DIOF DS SUSP used for?

DIOF DS SUSP is used to treat a wide range of bacterial and parasitic infections. This includes infections causing diarrhea, dysentery, and other infections affecting the teeth, lungs, gastrointestinal tract, urinary tract, and genital tract.

How does DIOF DS SUSP work?

DIOF DS SUSP contains two active ingredients: Ofloxacin and Metronidazole. Ofloxacin is a fluoroquinolone antibiotic that works by preventing bacterial cell division and inhibiting their repair mechanisms, leading to bacterial cell death. Metronidazole is effective against parasites and anaerobic bacteria; it works by damaging their DNA, which stops their growth and ultimately eliminates them. Both antibiotics are bactericidal and work together to effectively treat a broad spectrum of infections.

What is the usual dosage of DIOF DS SUSP?

The dosage of DIOF DS SUSP should always be as advised by your physician. It is typically taken orally twice a day, once in the morning and once in the evening. The dose and duration of treatment will depend on the type and severity of the infection, as well as the patient's age and body weight. If stomach upset occurs, it may be taken with food.

What are the possible side effects of DIOF DS SUSP?

Common side effects can include nausea, vomiting, abdominal pain or cramps, headache, dizziness, drowsiness, dry mouth, a metallic taste in the mouth, and loss of appetite. Rarely, more severe side effects like seizures or hallucinations may occur. If you experience severe allergic reactions such as swelling, difficulty breathing, or rash, discontinue the medication and seek urgent medical attention.

Is DIOF DS SUSP safe during pregnancy or breastfeeding?

DIOF DS SUSP is generally not recommended during pregnancy, especially in the first trimester, as it may cause harm to the fetus. It is also advised to avoid using DIOF DS SUSP while breastfeeding, as it may pass into breast milk and potentially affect the infant. Consult your doctor to assess the potential benefits and risks if you are pregnant, planning to become pregnant, or breastfeeding.

Can DIOF DS SUSP be taken with other medications?

DIOF DS SUSP can interact with several medications. Inform your doctor about all current medications, supplements, or herbal products to avoid potential drug interactions. Specifically, it may interact with antacids containing aluminum, calcium, or magnesium, certain medicines affecting the central nervous system (like phenytoin and lithium), and anticoagulants (such as warfarin), potentially increasing their effects. Concomitant use with non-steroidal anti-inflammatory drugs (NSAIDs) may increase the risk of CNS stimulation and seizures. Alcohol should be avoided during treatment and for at least three days after therapy, as it can cause a disulfiram-like reaction with symptoms like abdominal cramps, nausea, vomiting, and headaches.

What precautions should be taken with DIOF DS SUSP?

Caution is advised for patients with a history of epilepsy, tendon disorders, CNS disorders with a lowered seizure threshold, kidney disease, or severe liver disease, as dose adjustments may be needed. Patients with known allergies to ofloxacin, metronidazole, or other quinolone antibiotics should avoid this medication. Avoid exposure to strong sunlight and UV light, and ensure adequate hydration. If you experience pain or inflammation of a tendon, stop taking the medication and contact your doctor immediately.

What happens if a dose is missed?

If a dose of DIOF DS SUSP is missed, take it as soon as you remember. However, if it is almost time for the next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to compensate for a missed one.

How should DIOF DS SUSP be stored?

DIOF DS SUSP should be stored below 25°C (77°F) in a cool, dry place. It should be protected from light and moisture and kept out of the reach of children. Do not freeze the suspension. Shake well before use.