Histakind M Tab

HISTAKIND M TAB

Name:

• Brand Name: Histakind M Tablet
• Common Name: Montelukast and Fexofenadine combination tablet.

Composition: Each tablet contains:

• Montelukast: 10 mg
• Fexofenadine: 120 mg

Uses: Histakind M Tablet is an anti-allergic medication primarily used to manage symptoms of allergic rhinitis (seasonal and perennial allergies) in adults and adolescents aged 12 years and above (some sources say 15 years and above). It effectively relieves symptoms such as:

• Sneezing
• Runny nose
• Itchy or watery eyes
• Nasal congestion and stuffiness
• Itching and swelling associated with chronic hives (urticaria).

Dosage and Administration:

• Typically, it is taken orally once daily.
• The tablet can be taken with or without food.
• Swallow the tablet whole with a glass of water; do not crush, break, or chew it.
• The dosage and duration of treatment are determined by a doctor based on the patient's condition and response.
• It is advised to complete the entire course of treatment even if symptoms improve.

Side Effects: Common side effects may include:

• Headache
• Drowsiness or dizziness
• Nausea, vomiting, or diarrhea
• Skin rash
• Fatigue or weakness
• Upper respiratory tract infection
• Stomach pain.

Precautions:

• Allergies: Do not take if allergic to Montelukast, Fexofenadine, or any other components of the medicine.
• Driving & Alcohol: May cause drowsiness and dizziness; avoid driving or operating machinery and consuming alcohol, as it can worsen these effects.
• Pregnancy & Breastfeeding: Use during pregnancy only if considered essential by a doctor. Avoid while breastfeeding, though some sources suggest it's likely safe if prescribed.
• Kidney/Liver Disease: Use with caution in patients with kidney or liver problems.
• Drug Interactions:
  • Maintain a 2-hour gap between Histakind M and antacids containing magnesium and aluminum.
  • Inform your doctor if taking phenytoin, phenobarbital, rifampicin, or gemfibrozil.
• Food Interactions: Avoid taking with fruit juices (e.g., grapefruit, orange, apple) as they may reduce effectiveness.
• Children: Not recommended for children below 12 years of age.
• Allergy Tests: May interfere with the results of skin allergy tests; your doctor may advise discontinuation before such tests.

Storage:

• Store in a cool and dry place, away from direct sunlight.
• Keep out of sight and reach of children and pets.
• Store below 30°C.

What is Histakind M Tablet used for?

Histakind M Tablet is primarily used to treat the symptoms of allergic rhinitis, which can occur seasonally (like hay fever) or year-round. It helps alleviate symptoms such as sneezing, itchy or runny nose, nasal congestion, watery eyes, and itching. This medicine may also provide relief from chronic skin allergies like urticaria, helping to reduce itching, redness, and swelling. It is not intended for the treatment of acute asthma attacks.

How does Histakind M Tablet work?

Histakind M Tablet is a combination medication containing two active ingredients: Montelukast and Fexofenadine. Montelukast works as a leukotriene receptor antagonist, blocking the action of certain chemicals called leukotrienes that cause inflammation and increased mucus production in the airways, thereby reducing swelling and congestion. Fexofenadine is an antihistamine that works by blocking the action of histamine, a natural substance released during allergic reactions that causes symptoms like watery eyes, sneezing, and a runny nose.

What is the usual dosage for Histakind M Tablet?

The dosage of Histakind M Tablet should be precisely as directed by your doctor, as it can vary based on your medical condition and how you respond to the medication. The tablet should be swallowed whole with water and not crushed or chewed. It can be taken with or without food, but it is often recommended to take it at the same time each day to maintain consistent medication levels. It's important to complete the entire course of treatment as prescribed, even if your symptoms improve. This medicine is generally not recommended for children below 12 to 15 years of age.

What are the possible side effects of Histakind M Tablet?

Common side effects may include drowsiness, dizziness, headache, nausea, vomiting, diarrhea, fatigue, stomach pain, and upper respiratory tract infections. A skin rash or flu-like symptoms might also occur. Most of these side effects are usually mild and temporary, resolving as your body adjusts to the medicine. However, if any side effects persist or worsen, you should consult your doctor. Rarely, some individuals might experience mood changes, depression, self-harming thoughts, or aggressive behavior, in which case immediate medical attention is required. In case of an overdose, symptoms such as vomiting, thirst, severe headache, stomach pain, extreme tiredness, dry mouth, drowsiness, dizziness, and hyperactivity may occur, and you should seek emergency medical treatment.

Is Histakind M Tablet safe during pregnancy or breastfeeding?

During pregnancy, Histakind M Tablet should be used with caution and only if your doctor determines that the potential benefits outweigh the risks, as there may be undesirable effects on the fetus. For breastfeeding women, some sources suggest it appears in breast milk in very small amounts and may be safe, while others advise caution or state it is not recommended due to lack of safety data. Therefore, it is crucial to consult your doctor before taking this medicine if you are pregnant, planning a pregnancy, or breastfeeding.

Can Histakind M Tablet be taken with other medications?

Histakind M Tablet can interact with certain other medications. Antacids containing aluminum or magnesium hydroxide may reduce the absorption of fexofenadine, so it's advisable to maintain at least a 2-hour gap between taking Histakind M and these antacids. Certain antibiotics (e.g., erythromycin) and antifungal agents (e.g., ketoconazole, itraconazole, posaconazole) can increase the levels of fexofenadine or montelukast in your body, potentially leading to adverse effects. Medications like phenytoin, phenobarbital (for seizures), rifampicin (for tuberculosis), and gemfibrozil (for high cholesterol) should also be used cautiously with Histakind M. Always inform your doctor about all other medicines, supplements, or herbal products you are taking to prevent potential interactions.

What precautions should be taken while taking Histakind M Tablet?

It is important to inform your doctor if you have any pre-existing kidney or liver problems, as the medicine should be used with caution in such conditions. Since Histakind M Tablet can cause dizziness and drowsiness, you should avoid driving or operating heavy machinery until you understand how the medication affects you. Consuming alcohol while taking this medicine is not recommended, as it can worsen drowsiness and dizziness. Avoid taking this medicine with fruit juices like grapefruit, orange, or apple, as they may reduce its effectiveness. Additionally, inform your doctor if you have any known allergies to the components of Histakind M Tablet. This medication may interfere with skin allergy tests, so your doctor might advise you to stop taking it before such tests.

What happens if a dose is missed?

If you miss a dose of Histakind M Tablet, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed one.

How should Histakind M Tablet be stored?

Histakind M Tablet should be stored at room temperature, ideally below 25°C or below 30°C. Keep the medicine protected from direct light and moisture. Ensure it is stored securely out of the reach of children and pets. Always check the expiry date before use and dispose of any unused medicine properly.