Lupituss Syr.

LUPITUSS SYR. by LUPIN LTD-RESPIRA PULMONIS DIV

Name

• Brand Name: LUPITUSS SYR. (Lupituss Oral Suspension/Syrup)
• Manufacturer: Lupin Ltd.

Composition

• Active Ingredient: Levocloperastine (typically 20mg per 5ml)

Uses

Lupituss Syrup is an antitussive medication primarily used for the short-term treatment of dry cough. It works by blocking the cough receptor in the brain, which helps to suppress the cough reflex. It is indicated for non-productive coughs, meaning coughs without mucus or phlegm. It does not treat chronic coughs or those caused by smoking, emphysema, or asthma. Some sources also indicate its use for cough associated with allergies, common cold, and respiratory tract infections.

Dosage and Administration

Lupituss Syrup should be taken orally as prescribed by a doctor. The dose and duration depend on the patient's condition, age, and medical history. It can be taken with or without food. It is important to use a measuring cup or spoon for accurate dosing. Typically, it is prescribed for a short period until symptoms clear up. Avoid exceeding the recommended dose. For children, specific dosages vary; consult a pediatrician.

Side Effects

Common side effects may include:

• Nausea
• Drowsiness/Sleepiness
• Dizziness
• Dryness in the mouth
• Fainting
• Fatigue
• Headache
• Palpitations
• Gastrointestinal disturbance
• Confusion
• Numbness Most side effects are usually mild and temporary, resolving as the body adjusts to the medication.

Precautions

• Alcohol: Consumption of alcohol is unsafe and should be avoided as it can increase drowsiness and dizziness.
• Pregnancy & Breastfeeding: Information on use during pregnancy and breastfeeding is limited; consult a doctor. It is generally not recommended unless potential benefits outweigh risks.
• Driving & Operating Machinery: Lupituss Syrup can cause drowsiness or dizziness; avoid driving or activities requiring concentration if affected.
• Medical Conditions: Inform your doctor if you have a history of heart disease, hyperthyroidism, diabetes, kidney, or liver problems, or seizure disorders, as this medicine may worsen these conditions.
• Children: Not recommended for children under 2 years or 8 years without medical consultation.
• Allergies: Do not take if allergic to Lupituss Oral Suspension or levocloperastine.
• Fluid Intake: Increase fluid intake to help lubricate the throat.
• Consult a doctor if the cough persists for more than 7 days, returns, or occurs with fever, rash, or headache.

Storage

Store in a cool and dry place, away from direct sunlight. Keep out of sight and reach of children. Maintain storage temperatures between 10ºC to 25ºC or below 30ºC. Keep the container tightly closed to protect from air and moisture.

What is Lupituss Syrup used for?

Lupituss Syrup, containing levocloperastine, is primarily used for the symptomatic management of dry, non-productive coughs. This includes coughs associated with acute and chronic respiratory disorders such as bronchitis, upper respiratory tract infections, allergic rhinitis, asthma, and post-viral cough syndrome. It helps to relieve the urge to cough and can also alleviate allergic symptoms like a runny nose, sneezing, and throat irritation.

How does Lupituss Syrup work?

Lupituss Syrup works mainly by suppressing the cough reflex. Its active ingredient, levocloperastine, acts on the cough center in the brain to reduce its activity. Additionally, it can decrease the sensitivity of airway receptors that trigger coughing, has mild bronchodilator properties to relax and widen airways, and exhibits mild antihistaminic effects to help manage allergy-related coughs.

What is the usual dosage for Lupituss Syrup?

The dosage of Lupituss Syrup should always be as advised by your doctor, as it depends on individual factors like your condition severity and response to the medicine. It should be measured using the special dose-measuring spoon or cup provided, not a regular tablespoon. Typically, it is taken 2-3 times daily. It is not recommended for children under 2 years of age. For children aged 2-4 years, a common suggestion is 2 ml twice daily, and for 4-7 years, 3 ml twice daily, but these specific instructions should come from a healthcare professional.

What are the possible side effects of Lupituss Syrup?

Common side effects of Lupituss Syrup may include drowsiness or sleepiness, dizziness, nausea, vomiting, abdominal pain or discomfort, fatigue, palpitations (unusual awareness of your heartbeat), dryness in the mouth, headache, confusion, and numbness. If these side effects persist, worsen, or concern you, consult your doctor.

Is Lupituss Syrup safe during pregnancy or breastfeeding?

Lupituss Syrup is generally not recommended for use during pregnancy or by breastfeeding women because safety data in these groups is limited or not well-established. It might cross the placenta and potentially harm the unborn baby, or pass into breastmilk. If you are pregnant, planning pregnancy, or breastfeeding, it is crucial to consult your doctor before using this medicine.

Can Lupituss Syrup be taken with other medications?

Yes, Lupituss Syrup can interact with certain other medications. It may cause increased drowsiness when taken with central nervous system depressants, antihistamines, sedatives (e.g., zolpidem, diazepam), or tranquilizers. Co-administration with monoamine oxidase inhibitors (MAOIs) can lead to serious effects. It may also interact with sympathomimetic amines and antiserotonergic drugs. Always inform your doctor about all medicines, herbal preparations, and supplements you are currently taking to avoid possible drug interactions.

What precautions should be taken while using Lupituss Syrup?

Several precautions should be observed while taking Lupituss Syrup:

• Avoid driving or operating heavy machinery if you experience drowsiness or dizziness.
• Do not consume alcohol, as it can worsen dizziness and sleepiness.
• Use with caution if you have underlying conditions such as diabetes, heart disease (including hypertension and cardiovascular diseases), kidney or liver diseases, hyperthyroidism (overactive thyroid), or a history of seizures.
• It is not recommended for patients with excessive mucus discharge or limited mucociliary function.
• Inform your doctor if your cough does not improve within 7 days or if it is accompanied by fever, rash, or headache.

What happens if a dose of Lupituss Syrup is missed?

If you miss a dose of Lupituss Syrup, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to compensate for the missed one.

How should Lupituss Syrup be stored?

Lupituss Syrup should be stored in a cool and dry place, ideally below 30°C. Protect it from moisture, direct sunlight, and heat. Always keep the medicine out of the sight and reach of children and pets. Do not use it after the expiry date.