Galvus Od 100

GALVUS OD 100

GALVUS OD 100 is an oral antidiabetic medication manufactured by Novartis India Ltd., prescribed for the management of Type 2 Diabetes Mellitus.

• Name:

  • Common Name: Vildagliptin
  • Brand Name: GALVUS OD 100

• Composition:

  • Active Ingredient: Each tablet contains Vildagliptin 100 mg.
  • Excipients: Lactose anhydrous, microcrystalline cellulose, sodium starch glycolate, magnesium stearate.

• Uses: GALVUS OD 100 is indicated for adults with Type 2 Diabetes Mellitus (T2DM) to improve glycemic control. It is used as an adjunct to diet and exercise and can be prescribed:

  • As monotherapy.
  • In initial combination with metformin when diet and exercise alone are insufficient.
  • In combination with other antidiabetic medicinal products, including insulin, when these do not provide adequate glycemic control. It works by increasing the production of insulin from the pancreas and decreasing glucagon, thereby lowering blood glucose levels.

• Dosage and Administration: The recommended dose for GALVUS OD 100 Tablet is typically 100 mg once daily, as implied by "OD" (Once Daily) in its name, and supported by specific product information. It can be taken with or without meals. If a dose is missed, it should be taken as soon as the patient remembers, but a double dose should not be taken on the same day.

• Side Effects:

  • Common: Headache, dizziness, nausea, excessive sweating, low blood sugar levels (hypoglycemia, especially in combination therapy), trembling, nasopharyngitis (common cold), cough, constipation, fatigue, peripheral edema, and joint pain.
  • Serious (Rare): Acute pancreatitis, hepatic dysfunction (including hepatitis), and hypersensitivity reactions such as rash, hives, or angioedema.

• Precautions:

  • Not for use in patients with Type 1 Diabetes Mellitus or diabetic ketoacidosis.
  • Not recommended for patients with hepatic impairment, including those with pre-treatment ALT or AST levels >2.5-3 times the upper limit of normal. Liver function tests should be performed before initiating treatment.
  • Caution is advised in patients with moderate to severe renal impairment, where dose adjustment may be required.
  • The risk of hypoglycemia increases when used in combination with a sulfonylurea; a lower dose of the sulfonylurea may be considered.
  • Contains lactose; patients with rare hereditary problems of galactose intolerance should not take this medicine.
  • May cause dizziness; patients should be cautious when driving or operating machinery.
  • Consult a doctor if pregnant or breastfeeding.

• Storage: Store below 30°C. Protect from moisture. Keep out of sight and reach of children.

GALVUS OD 100 by NOVARTIS INDIA LTD

What is GALVUS OD 100 used for?

GALVUS OD 100 is an oral antidiabetic medication primarily used to manage type 2 diabetes mellitus in adults. It is prescribed when diet and exercise alone are not sufficient to control blood sugar levels, and can be used as a standalone treatment or in combination with other diabetes medicines.

How does GALVUS OD 100 work?

GALVUS OD 100 contains Vildagliptin, which belongs to a class of medicines called Dipeptidyl Peptidase-4 (DPP-4) inhibitors. It works by preventing the breakdown of natural hormones called incretins (GLP-1 and GIP) that are released after meals. By preserving incretin hormones, it helps to increase insulin production from the pancreas when needed and decreases glucagon production from the liver, thereby lowering both fasting and post-meal blood sugar levels.

What is the usual dosage of GALVUS OD 100?

The maximum recommended daily dose of GALVUS OD 100 is 100 mg. Your doctor will determine the appropriate dosage based on your condition and response to treatment. It can be taken once daily as 100 mg, or as two divided doses of 50 mg in the morning and evening. It can be taken with or without food.

What are the possible side effects of GALVUS OD 100?

Common side effects may include low blood glucose levels (hypoglycemia), headache, dizziness, nausea, excessive sweating, and trembling. It is important to recognize the symptoms of hypoglycemia (e.g., lightheadedness, sweating, dry mouth, fast heartbeat) and have sugary food or juice available to manage them. More serious but rare side effects could include acute pancreatitis and severe allergic reactions. If any side effects persist or worsen, consult your doctor.

Is GALVUS OD 100 safe during pregnancy or breastfeeding?

GALVUS OD 100 is generally not recommended during pregnancy due to insufficient experience in pregnant women. It is also not recommended for breastfeeding mothers as it is not known whether Vildagliptin is excreted in human milk. Always consult your doctor if you are pregnant, planning a pregnancy, or breastfeeding before taking this medication.

Can GALVUS OD 100 be taken with other medications?

GALVUS OD 100 can be used in combination with other antidiabetic medications such as metformin, sulfonylureas, or thiazolidinediones to achieve better blood sugar control. However, when taken with sulfonylureas, there may be an increased risk of hypoglycemia, and your doctor might adjust the dosage of the sulfonylurea. Close monitoring is advised if taken with digoxin (a heart medicine). Vildagliptin generally has a low potential for drug interactions as it does not significantly interact with common liver enzymes.

What precautions should be taken while using GALVUS OD 100?

• GALVUS OD 100 is not for type 1 diabetes or diabetic ketoacidosis.
• Exercise caution and inform your doctor if you have kidney or liver disease; dosage adjustments may be necessary, and it may not be recommended in severe cases.
• Inform your doctor if you have a history of heart disease or pancreatitis.
• Avoid alcohol consumption as it can interfere with blood sugar levels.
• This medication may cause dizziness, so be cautious when driving or operating machinery until you know how it affects you.
• Regular monitoring of your kidney and liver function, as well as blood glucose levels, will be advised by your doctor.
• Do not stop taking GALVUS OD 100 abruptly without consulting your doctor, as this can lead to an increase in blood sugar levels.
• It is not recommended for use in children below 18 years of age.

What happens if a dose of GALVUS OD 100 is missed?

If you miss a dose of GALVUS OD 100, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed one.

How should GALVUS OD 100 be stored?

GALVUS OD 100 should be stored in a cool and dry place, away from direct sunlight and moisture, at room temperature (below 25°C or 30°C). Keep it in its original packaging and safely out of the reach of children.