Prothiaden M 50 Tablet

PROTHIADEN M 50 TABLET

PROTHIADEN M 50 TABLET is a prescription medicine manufactured by Abbott India Ltd..

• Name:

  • Brand Name: Prothiaden M 50 Tablet
  • Common Name: Dosulepine and Methylcobalamin Tablet

• Composition: Each tablet contains:

  • Dosulepine (Dothiepin): 50 mg
  • Methylcobalamin (Mecobalamin): 1500 mcg

• Uses: PROTHIADEN M 50 TABLET is primarily used in the treatment of:

  • Depression and anxiety disorders
  • Neuropathic pain (long-lasting pain caused by nerve damage due to conditions like diabetes, shingles, or spinal cord injury)
  • Support in vitamin B12 deficiency, which can contribute to nerve damage and mood disorders

• Dosage and Administration: Take PROTHIADEN M 50 TABLET exactly as prescribed by your doctor. It can be taken with or without food, but it is advisable to take it at the same time each day to maintain a consistent level of medicine in the body. Swallow the tablet whole with a glass of water; do not crush, break, or chew it. The doctor determines the dose based on health conditions, with a single maximum dose of 25 mg taken three times daily, which can be gradually increased up to 150 mg per day. Do not stop taking this medicine suddenly, as abrupt withdrawal can cause mood changes or irritability.

• Side Effects:

  • Common Side Effects: Dry mouth, blurred vision, headache, increased or decreased appetite, nausea or vomiting, diarrhea, changes in heartbeat, constipation, difficulty in passing urine, sweating, drowsiness, dizziness, and weight gain.
  • Serious Side Effects: Rapid or irregular heartbeat, chest pain, severe headache, confusion, yellowing of the skin or eyes (possible liver problem), thoughts of self-harm, persistent constipation or difficulty urinating, and allergic reactions such as swelling, rash, or trouble breathing. Seek immediate medical attention if these occur.

• Precautions:

  • Avoid alcohol consumption as it may worsen side effects like drowsiness.
  • Use with caution in pregnant or breastfeeding mothers (consult a doctor).
  • It may cause drowsiness and affect concentration; avoid driving or operating heavy machinery until you know how it affects you.
  • Inform your doctor if you have heart, liver, or kidney problems, epilepsy, a history of suicidal thoughts, bipolar disorder, diabetes, glaucoma, or prostate issues.
  • Not recommended for use with Monoamine Oxidase Inhibitors (MAOIs).
  • Caution is advised in young adults due to an increased risk of suicidal thoughts.

• Storage: Store the medicine in a cool, dry place, below 25°C or 30°C, and out of the sight and reach of children.

PROTHIADEN M 50 TABLET by ABBOTT

What is Prothiaden M 50 Tablet used for?

Prothiaden M 50 Tablet is a combination medication primarily used to treat neuropathic pain, which is chronic pain caused by nerve damage from conditions like diabetes, shingles, or spinal cord injury. It is also used to treat depression and feelings of anxiety, especially when other treatments are not suitable, and can help address vitamin B12 deficiency.

How does Prothiaden M 50 Tablet work?

This medicine contains two active ingredients: Dosulepin and Methylcobalamin. Dosulepin is a tricyclic antidepressant that works by increasing the activity of neurotransmitters like serotonin and noradrenaline in the brain. These chemicals play a crucial role in regulating mood, memory, alertness, and concentration. Methylcobalamin, a form of vitamin B12, helps in addressing vitamin B12 deficiency, protecting nerve fibers from damage, and aiding in the repair of damaged nerves, which contributes to pain relief and mood improvement.

What is the usual dosage for Prothiaden M 50 Tablet?

The dosage of Prothiaden M 50 Tablet is determined by a healthcare professional based on individual health conditions, age, and body weight. It is generally recommended to take this medication consistently at the same time each day, with or without food, to maintain a steady level in the body. The tablet should be swallowed whole and not crushed, broken, or chewed. For depression, a typical daily dosage may range from 50mg to 150mg, potentially increasing gradually.

What are the possible side effects of Prothiaden M 50 Tablet?

Common side effects may include constipation, dry mouth, drowsiness, blurred vision, increased heart rate, difficulty in urination, weight gain, headache, changes in appetite, nausea, vomiting, and diarrhea. It may also cause dizziness and sedation, affecting activities that require focus. Serious side effects are less common but can include rapid or irregular heartbeat, chest pain, severe headache, confusion, yellowing of the skin or eyes (indicating a possible liver problem), thoughts of self-harm, persistent constipation, difficulty urinating, or allergic reactions.

Is Prothiaden M 50 Tablet safe during pregnancy or breastfeeding?

Prothiaden M 50 Tablet is generally not recommended for use during pregnancy unless absolutely necessary, as animal studies have shown harmful effects on the developing baby. For breastfeeding mothers, it is considered probably unsafe as limited human data suggests the drug may pass into breast milk and potentially harm the baby. The risks and benefits should be thoroughly discussed with a doctor, who may prescribe a safer alternative.

Can Prothiaden M 50 Tablet be taken with other medications?

Taking Prothiaden M 50 Tablet with other antidepressant or antipsychotic medicines can lead to serious, life-threatening side effects. It is also not recommended for use with Monoamine Oxidase Inhibitors (MAOIs) due to an increased risk of seizures, fever, hallucinations, and rarely death; a minimum gap of 14 days should be observed between taking these medications. Interactions can also occur with antibiotics, antifungals, migraine medicines, stomach ulcer medications, antimalarial medicines, heart medicines, and blood thinners. It is crucial to inform your doctor about all medications, including herbal supplements, you are currently taking.

What precautions should be taken while using Prothiaden M 50 Tablet?

Caution is advised as Prothiaden M 50 Tablet can cause drowsiness, dizziness, and blurred vision; avoid driving or operating heavy machinery until you understand how it affects you. Alcohol consumption should be avoided as it can worsen side effects. The medication should be used with caution in patients with liver or kidney diseases, heart conditions (like irregular heartbeat or recent heart attack), glaucoma, prostate issues, epilepsy, bipolar disorder (especially during a manic phase), or a history of suicidal thoughts. Young adults should be monitored closely as it may worsen depression and lead to suicidal thoughts. Abruptly stopping the medication is not advised and can cause withdrawal symptoms.

What happens if a dose of Prothiaden M 50 Tablet is missed?

If a dose of Prothiaden M 50 Tablet is missed, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one. It is important to complete the full course of treatment even if symptoms improve.

How should Prothiaden M 50 Tablet be stored?

Prothiaden M 50 Tablet should be stored in a cool and dry place, away from direct sunlight, heat, and moisture. It should be kept at a temperature below 25°C and out of the sight and reach of children and pets.