Sr Pevesca Plus 75 Mg Tablet (10 Tab)

SR PEVESCA PLUS 75 MG TABLET

SR Pevesca Plus 75 Tablet is a combination medication manufactured by USV Private Limited, primarily prescribed for the management of neuropathic pain.

• Composition Each SR Pevesca Plus 75 Tablet contains a blend of four active ingredients:

  • Pregabalin (75 mg)
  • Methylcobalamin (Mecobalamin) (1500 mcg)
  • Vitamin B6 (Pyridoxine) (20 mg)
  • Folic Acid (5 mg)

• Uses SR Pevesca Plus 75 Tablet is primarily used to treat neuropathic pain, which is chronic nerve pain often caused by conditions such as diabetes (diabetic neuropathy), shingles (postherpetic neuralgia), or spinal cord injury. It helps in decreasing pain sensation, protecting damaged nerve cells, and providing essential nutrients to the nerves. It may also be used in conditions like fibromyalgia, epilepsy, and anxiety.

• Dosage and Administration This medicine should be taken exactly as prescribed by a doctor. It can be taken with or without food, but it is advisable to take it at a fixed time daily for consistent medication levels. The tablet should be swallowed whole with a glass of water and not crushed, chewed, or broken. Dosage and duration depend on the medical condition and response to treatment. For neuropathic pain, an initial dose of 75 mg twice daily is sometimes advised, with a maximum daily dose of 600 mg in divided doses. Do not discontinue the medication suddenly without consulting your doctor.

• Side Effects Common side effects may include dizziness, tiredness, sleepiness, uncoordinated body movements (ataxia), headache, nausea, and weight gain. Other possible side effects include constipation and euphoria. Serious side effects, though less common, can include severe allergic reactions (rash, itching, swelling, trouble breathing), mood changes, severe drowsiness, or unsteady movements. If any side effects persist or worsen, medical attention should be sought.

• Precautions

  • Pregnancy and Breastfeeding: Consult a doctor before use if pregnant or breastfeeding, as the safety in these cases is not well-established.
  • Alcohol: Avoid alcohol consumption while taking this medicine, as it can increase dizziness and sleepiness.
  • Driving and Machinery: This medicine can cause dizziness, sleepiness, and uncoordinated body movements; therefore, avoid driving or operating heavy machinery until you understand how it affects you.
  • Medical Conditions: Inform your doctor about any pre-existing medical conditions, especially kidney or liver impairment, congestive heart failure, or a history of depression, seizures, or substance abuse. Dose adjustments may be necessary for patients with kidney or liver issues.
  • Interactions: Inform your doctor about all other medications being taken to prevent potential drug interactions, especially with painkillers like tramadol, as co-administration can cause serious breathing problems.
  • Children: Safety and effectiveness have not been established for children, so it should not be given to them unless specifically advised by a doctor.
  • Overdose: Symptoms of overdose may include sleepiness, confusion, restlessness, and agitation. Seek immediate medical attention if an overdose is suspected.

• Storage Store at room temperature, typically between 20-25°C. Protect the medicine from moisture and light. Keep out of the sight and reach of children.

What is SR PEVESCA PLUS 75 MG TABLET used for?

SR PEVESCA PLUS 75 MG TABLET is primarily used to treat neuropathic pain, which is chronic nerve pain resulting from conditions like diabetes, shingles (herpes zoster), or spinal cord injury. It may also be prescribed for epilepsy/seizures, fibromyalgia, diabetic neuropathy, postherpetic neuralgia, megaloblastic anemia, and generalized anxiety disorder.

How does SR PEVESCA PLUS 75 MG TABLET work?

This medicine is a combination of four active ingredients: Pregabalin, Mecobalamin (Methylcobalamin), Folic Acid, and Pyridoxine (Vitamin B6). Pregabalin acts as an anticonvulsant, calming damaged or overactive nerves and reducing pain signals by modulating calcium channel activity in nerve cells. Mecobalamin and Pyridoxine are forms of Vitamin B that help in the reconstruction and protection of damaged nerve cells by aiding in the production of myelin, a substance that covers and protects nerve fibers. Folic Acid, another B vitamin, provides essential nutrients to the nerves, supporting their overall health.

What is the usual dosage for SR PEVESCA PLUS 75 MG TABLET?

The dosage of SR PEVESCA PLUS 75 MG TABLET should be strictly as prescribed by your doctor. It is typically taken once or twice daily, with or without food, but it's best to take it at the same time each day to maintain a consistent level of medication in your body. Swallow the tablet whole; do not chew, crush, or break it. For neuropathic pain, an initial dose of 75 mg twice daily may be prescribed.

What are the possible side effects of SR PEVESCA PLUS 75 MG TABLET?

Common side effects include dizziness, tiredness, sleepiness, uncoordinated body movements, headache, blurred or double vision, dry mouth, and weight gain. Some individuals may experience constipation, euphoria, confusion, restlessness, agitation, nausea, vomiting, or abdominal pain. More serious but rare side effects can include severe allergic reactions (e.g., rash, itching, swelling, trouble breathing), mood changes, severe drowsiness, unsteady movements, and suicidal thoughts. If any side effects persist, worsen, or if you experience severe symptoms, consult your doctor immediately.

Is SR PEVESCA PLUS 75 MG TABLET safe during pregnancy or breastfeeding?

SR PEVESCA PLUS 75 MG TABLET is generally not recommended during pregnancy unless absolutely necessary and prescribed by a doctor after carefully assessing the potential benefits and risks. Animal studies have indicated harmful effects on the developing baby. For breastfeeding women, the use of this medication is also generally not recommended. If its use is considered essential, breastfeeding may need to be discontinued. Always consult your doctor before taking this medicine if you are pregnant or breastfeeding.

Can SR PEVESCA PLUS 75 MG TABLET be taken with other medications?

It is crucial to inform your doctor about all other medications, supplements, and herbal products you are currently taking to avoid potential drug interactions. Avoid consuming alcohol while taking SR PEVESCA PLUS 75 MG TABLET, as it can significantly increase dizziness and sleepiness. Caution is advised when taking this medicine with other CNS depressants, antidepressants, or anticonvulsants. Co-administration with opiate pain medicines (e.g., tramadol, oxycodone) can lead to severe dizziness, confusion, lack of coordination, breathing problems, drowsiness, and even coma, so dosage adjustments by a doctor are necessary. Inform your doctor if you are taking medications for blood sugar control (like Pioglitazone) as the combination can increase the risk of weight gain, fluid retention, and heart failure. While it has a low potential for interaction with blood thinners, it's still important to inform your doctor.

What precautions should be taken while using SR PEVESCA PLUS 75 MG TABLET?

Before starting this medication, inform your doctor if you have any allergies, kidney or liver disease, heart problems, bipolar syndrome, depression, seizures, or a history of alcohol or substance abuse. Since this medicine can cause drowsiness and dizziness, do not drive or operate heavy machinery until you know how it affects you. It is also advisable to rise slowly from a sitting or lying position to prevent dizziness. Do not stop taking the medication suddenly without consulting your doctor, as abrupt discontinuation can lead to withdrawal symptoms such as anxiety, sleeping difficulties, nausea, pain, and sweating. The dosage should be gradually reduced under medical supervision. Monitor for any unusual changes in mood or behavior, new or worsening depression, or suicidal thoughts, and report them to your doctor immediately. SR PEVESCA PLUS 75 MG TABLET is not recommended for children as its safety and effectiveness have not been established. Caution is also advised for elderly patients (aged 75 years or above) and those with respiratory conditions like asthma or COPD.

What happens if a dose of SR PEVESCA PLUS 75 MG TABLET is missed?

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed one.

How should SR PEVESCA PLUS 75 MG TABLET be stored?

SR PEVESCA PLUS 75 MG TABLET should be stored at room temperature, typically between 20-25°C. Keep it in its original packaging, tightly closed, and protect it from moisture and light. Ensure the medicine is kept out of the sight and reach of children.