Sitadapa 100 Mg/10 Mg Tablet (10 Tab)

SITADAPA 100 MG/10 MG TABLET is a medication manufactured by Macleods Pharmaceuticals Ltd. designed for the management of type 2 diabetes mellitus.

Name

• Brand Name: Sitadapa 100 mg/10 mg Tablet
• Common Name: Dapagliflozin and Sitagliptin Tablets

Composition

Each tablet contains:

• Dapagliflozin: 10 mg
• Sitagliptin: 100 mg

Uses

SITADAPA 100 MG/10 MG TABLET is primarily used to treat type 2 diabetes mellitus in adults, particularly when diet, exercise, and other medications alone do not adequately control blood sugar levels. It works by helping the body utilize insulin effectively, lowering blood sugar, and removing excess sugar through urine. This medication also aids in preventing serious diabetes complications such as eyesight loss, kidney damage, nerve damage, and diabetic foot ulcers. Additionally, it is used to treat chronic kidney disease in adults with reduced kidney function.

Dosage and Administration

SITADAPA 100 MG/10 MG TABLET should be taken orally, with or without food, usually once daily in the morning. It is crucial to take the medicine at the same time each day to maintain consistent blood levels and ensure optimal benefits. The exact dosage will be determined by a doctor based on the patient's medical condition and response to treatment. Patients should not exceed the recommended dose or stop taking the medication abruptly without consulting their doctor, as this can lead to increased blood sugar levels and a higher risk of complications.

Side Effects

Common side effects may include:

• Diarrhea
• Hypoglycemia (low blood sugar), especially when used with other antidiabetic medicines or alcohol, or if meals are delayed/missed
• Headache
• Nausea and vomiting
• Frequent or increased urination
• Dizziness or light-headedness
• Urinary tract infections (UTIs)
• Fungal infections in the genital area
• Nasal congestion and sore throat
• Flatulence and constipation

Serious side effects, though less common, warrant immediate medical attention, such as symptoms of acute pancreatitis (severe abdominal pain with or without nausea/vomiting) or severe allergic reactions (rash, swelling of face/lips/tongue/throat).

Precautions

• Contraindications: Not recommended for patients with type 1 diabetes mellitus, severe kidney or liver disease, or those on dialysis.
• Pregnancy and Breastfeeding: Consult a doctor before use; it should only be used if clearly necessary during pregnancy, and caution is advised during breastfeeding.
• Drug Interactions: Use with caution with diuretics (e.g., furosemide, hydrochlorothiazide) as it may increase the risk of dehydration and low blood pressure. Concomitant use with insulin or insulin secretagogues (e.g., sulfonylureas) may cause extremely low blood sugar levels, requiring dose adjustments.
• Other Warnings: Inform your doctor about any history of liver disease, kidney disease, heart disease, urinary tract infections, pancreatitis, gallstones, or alcohol dependence. Maintain good hygiene to prevent genital fungal infections. Regular monitoring of blood sugar levels is crucial.

Storage

Store in a cool and dry place, away from direct sunlight. Keep the tablets out of the sight and reach of children. Maintain storage at room temperature, ideally below 30°C.

What is SITADAPA 100 MG/10 MG TABLET used for?

SITADAPA 100 MG/10 MG TABLET is primarily used to manage type 2 diabetes mellitus in adults. It is prescribed when diet and exercise alone, or other single medications, are not sufficient to control blood sugar levels. Additionally, it may help reduce the risk of cardiovascular death and slow the progression of kidney disease in certain patients.

How does SITADAPA 100 MG/10 MG TABLET work?

This medicine contains two active ingredients: Sitagliptin (100 mg) and Dapagliflozin (10 mg). Dapagliflozin is an SGLT2 inhibitor that works by blocking the reabsorption of glucose in the kidneys, leading to increased excretion of excess sugar through urine. Sitagliptin is a DPP-4 inhibitor that increases the levels of natural hormones called incretins, which stimulate the pancreas to produce more insulin when blood sugar levels are high and reduce the amount of glucose produced by the liver. Together, they work through different mechanisms to lower blood glucose.

What is the usual dosage for SITADAPA 100 MG/10 MG TABLET?

The typical dosage for SITADAPA 100 MG/10 MG TABLET is one tablet (100 mg Sitagliptin / 10 mg Dapagliflozin) taken once daily. It can be taken with or without food, but it is recommended to take it at the same time each day to maintain consistency. Your doctor may adjust the dosage based on your individual condition and kidney function.

What are the possible side effects of SITADAPA 100 MG/10 MG TABLET?

Common side effects include urinary tract infections (UTIs), genital fungal infections, increased urination, headache, nasopharyngitis (cold-like symptoms), nausea, vomiting, diarrhea, constipation, and dizziness. Low blood sugar (hypoglycemia) can also occur, especially when taken with other diabetes medications like insulin or sulfonylureas. Serious but less common side effects can include dehydration, diabetic ketoacidosis, and pancreatitis.

Is SITADAPA 100 MG/10 MG TABLET safe during pregnancy or breastfeeding?

SITADAPA 100 MG/10 MG TABLET is generally not recommended during pregnancy or breastfeeding due to limited information on its effects on a developing baby or on breast milk. If you are pregnant, planning pregnancy, or breastfeeding, it is crucial to consult your doctor, as they may suggest safer alternative treatments.

Can SITADAPA 100 MG/10 MG TABLET be taken with other medications?

This medicine can interact with other medications. Concomitant use with diuretics (water pills like furosemide) may increase the risk of dehydration and low blood pressure. When taken with insulin or insulin secretagogues (like sulfonylureas), there is an increased risk of hypoglycemia (low blood sugar), and dose adjustments of those medications may be necessary. It is important to inform your doctor about all other medications, herbal supplements, or vitamins you are taking to avoid potential interactions.

What precautions should be taken while using SITADAPA 100 MG/10 MG TABLET?

Do not take this medicine if you have type 1 diabetes mellitus, severe kidney disease, or a history of serious allergic reactions to its components. Use with caution if you have heart problems or a history of pancreatitis. It's important to stay well-hydrated to reduce the risk of dehydration due to increased urination. Regular monitoring of blood sugar levels is essential. Do not stop taking the medication abruptly without consulting your doctor, as this can lead to an increase in blood sugar and associated complications. Avoid alcohol consumption as it may increase the risk of serious side effects like ketoacidosis.

What happens if a dose of SITADAPA 100 MG/10 MG TABLET is missed?

If you miss a dose, take it as soon as you remember, unless it is almost time for your next scheduled dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a forgotten one.

How should SITADAPA 100 MG/10 MG TABLET be stored?

SITADAPA 100 MG/10 MG TABLET should be stored in a cool, dry place, away from direct sunlight and moisture. Keep it out of the sight and reach of children.