Vildamac M 50/500

VILDAMAC M 50/500 Tablet

Name

Brand Name: VILDAMAC M 50/500 Tablet Manufacturer: Macleods Pharmaceuticals Ltd.

Composition

Each tablet contains:

• Vildagliptin: 50 mg
• Metformin Hydrochloride: 500 mg

Uses

VILDAMAC M 50/500 Tablet is a combination medication primarily used for the treatment of Type 2 diabetes mellitus in adults. It is prescribed when diet and exercise alone are insufficient to control blood sugar levels. This medication helps in:

• Controlling high blood sugar levels.
• Making the pancreas produce more insulin and less glucagon.
• Improving the body's sensitivity to insulin and reducing glucose production by the liver.
• Preventing serious complications associated with diabetes, such as kidney damage, eye damage (retinopathy), nerve problems (neuropathy), and reducing the risk of heart attack or stroke.

Dosage and Administration

Take VILDAMAC M 50/500 Tablet exactly as directed by your doctor.

• It should be swallowed whole with water; do not crush, chew, or break the tablet.
• It is generally recommended to take the tablet with or after meals to minimize stomach upset.
• For optimal results, take it at the same time each day.
• Do not stop taking the medicine without consulting your doctor.

Side Effects

Common Side Effects:

• Hypoglycemia (low blood glucose levels), characterized by dizziness, sweating, hunger pangs, dry mouth, headache, trembling, or weakness.
• Nausea, vomiting, diarrhea, stomach pain.
• Changes in taste, metallic taste.
• Loss of appetite.
• Upper respiratory symptoms.
• Joint pain, tiredness, constipation.
• Swollen hands, ankles, or feet (oedema).

Serious Side Effects (Seek immediate medical attention if experienced):

• Lactic acidosis: Symptoms include stomach discomfort, decreased appetite, diarrhea, fast or shallow breathing, muscle pain or cramps, sleepiness, tiredness, or weakness.
• Inflamed pancreas: Severe and persistent pain in the abdomen, with or without nausea or vomiting.

Precautions

• Contraindications: Do not use if you have Type 1 diabetes, diabetic ketoacidosis, severe kidney impairment, severe liver disease, congestive heart failure, or a known allergy to any components.
• Alcohol: Avoid consuming alcohol, as it can increase the risk of lactic acidosis and further lower blood glucose levels.
• Pregnancy and Breastfeeding: Not recommended during pregnancy or while breastfeeding. Consult your doctor.
• Other Conditions: Inform your doctor if you have kidney disease, liver disease, heart problems (e.g., irregular heartbeat, heart failure), a history of pancreatitis, or low vitamin B12 levels.
• Pediatric Use: Not recommended for patients below 18 years of age.
• Monitoring: Regular monitoring of kidney function and blood sugar levels is necessary during treatment.

Storage

Store in a cool and dry place, protected from direct sunlight, moisture, and heat. Keep out of sight and reach of children. Ideally, store below 25°C or below 30°C.

VILDAMAC M 50/500 Tablet is a combination medication used to manage type 2 diabetes mellitus. It contains Vildagliptin (50mg) and Metformin (500mg), which work together to help control blood sugar levels.

Here are some frequently asked questions about VILDAMAC M 50/500 Tablet:

What is VILDAMAC M 50/500 used for?

VILDAMAC M 50/500 Tablet is used to treat type 2 diabetes mellitus in adults when diet and exercise alone are not enough to control blood sugar levels. It helps prevent serious complications of diabetes such as kidney damage, vision impairment, nerve damage, and may reduce the risk of heart attack or stroke.

How does VILDAMAC M 50/500 work?

This medicine combines two active ingredients: Vildagliptin and Metformin. Vildagliptin works by inhibiting an enzyme called DPP-4, which leads to increased production of insulin by the pancreas and decreased levels of glucagon (a hormone that raises blood sugar). Metformin works by reducing the amount of glucose produced by the liver, decreasing glucose absorption from the intestines, and increasing the body's sensitivity to insulin.

What is the usual dosage for VILDAMAC M 50/500?

The usual dosage is typically one tablet (50mg Vildagliptin/500mg Metformin) taken twice daily. It should be taken with meals to minimize stomach upset. Your doctor will determine the appropriate dose based on your individual condition, blood sugar levels, and other medications you are taking.

What are the possible side effects of VILDAMAC M 50/500?

Common side effects can include hypoglycemia (low blood glucose levels), nausea, vomiting, diarrhea, stomach pain, headache, loss of appetite, metallic taste, and weakness. Less common but serious side effects include lactic acidosis (a rare but severe condition associated with Metformin), pancreatitis, and certain skin reactions.

Is VILDAMAC M 50/500 safe during pregnancy or breastfeeding?

VILDAMAC M 50/500 Tablet is generally not recommended during pregnancy as it may harm the fetus. It is also likely unsafe during breastfeeding because its components may pass into breast milk and affect the baby. Always consult your doctor if you are pregnant, planning to become pregnant, or breastfeeding.

Can VILDAMAC M 50/500 be taken with other medications?

VILDAMAC M 50/500 can interact with certain medications, including glucocorticoids, diuretics, beta-blockers, and thyroid products. Concomitant use with ACE inhibitors may increase the risk of angioedema. Inform your doctor about all medications, supplements, and herbal products you are taking to avoid potential interactions.

What precautions should be taken while using VILDAMAC M 50/500?

This medicine is not suitable for individuals with type 1 diabetes or diabetic ketoacidosis. Inform your doctor if you have a history of kidney disease, liver disease, heart conditions, pancreatitis, or low vitamin B12 levels. Excessive alcohol consumption should be avoided as it can increase the risk of lactic acidosis. Regular monitoring of kidney function and blood sugar levels is essential. It may also cause dizziness, so caution is advised when driving or operating machinery.

What happens if a dose of VILDAMAC M 50/500 is missed?

If you miss a dose, take it as soon as you remember, preferably with food. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.

How should VILDAMAC M 50/500 be stored?

Store VILDAMAC M 50/500 Tablet at room temperature, typically below 30°C. Keep it away from moisture, heat, and direct sunlight, and always out of reach of children.