Brutacef O Tab

BRUTACEF O TAB

BRUTACEF O TAB, manufactured by MANKIND - PHARMA DIV, is a combination antibiotic medication used to treat a variety of bacterial infections.

Composition Each tablet typically contains:

• Cefixime: 200 mg
• Ofloxacin: 200 mg

Uses BRUTACEF O TAB is primarily prescribed for the treatment of various bacterial infections, including:

• Urinary tract infections (UTIs)
• Typhoid fever
• Respiratory tract infections (e.g., bronchitis, pneumonia, sinusitis, tonsillitis, pharyngitis)
• Skin and soft tissue infections
• Sexually transmitted diseases (STDs) such as chlamydia and gonorrhea
• Infections of the ears, lungs, and prostate It is important to note that this medicine is not effective against viral infections like the common cold or flu.

Dosage and Administration

• Take BRUTACEF O TAB orally as prescribed by your doctor.
• It can be taken with or without food, but it is advisable to take it at a fixed time each day for better efficacy.
• Swallow the tablet whole; do not chew, crush, or break it.
• Complete the full course of treatment, even if symptoms improve, to prevent the infection from returning and to avoid antibiotic resistance.
• The usual adult dose for the combination of Cefixime (200mg) and Ofloxacin (200mg) is often one tablet twice daily, but this may vary based on the infection's type and severity.

Side Effects Common side effects may include:

• Diarrhea, loose stools
• Nausea, vomiting
• Abdominal pain, indigestion, stomach pain
• Headache, dizziness, weakness
• Skin rash

More serious side effects, though less common, can include:

• Allergic reactions (e.g., severe rash, itching, swelling of face/lips/tongue, difficulty breathing)
• Tendinitis or tendon rupture
• Peripheral neuropathy (nerve damage in legs)
• Myasthenia gravis aggravation
• Changes in blood test results (e.g., elevated liver enzymes, decreased white blood cell count)

Precautions

• Allergies: Do not take if you have a known allergy to Cefixime, Ofloxacin, other cephalosporin antibiotics, fluoroquinolone antibiotics, or any macrolide antibiotics.
• Pregnancy and Breastfeeding: Not generally recommended during pregnancy or breastfeeding unless specifically advised by a doctor after careful assessment of benefits and risks.
• Kidney and Liver Conditions: Use with caution in patients with kidney or liver disease. Dosage adjustments may be necessary. It is generally not allowed for patients with severe kidney or liver problems or those already on other antibiotics.
• Central Nervous System Disorders: Use with caution if you have a history of seizure disorders (epilepsy), nerve problems, depression, or other psychotic disorders, as it may worsen these conditions.
• Diabetes: May lower blood sugar levels in some individuals.
• Driving and Operating Machinery: This medicine may cause dizziness, confusion, or impaired vision. Avoid driving or operating heavy machinery if you experience these effects.
• Alcohol: Avoid alcohol consumption while taking this medicine as it may increase side effects like drowsiness.
• Drug Interactions: Inform your doctor about all current medications, including over-the-counter drugs, supplements, and herbal products. Avoid taking antacids within 2 hours of this medicine. Dairy products may interfere with Ofloxacin absorption.
• Photosensitivity: This medicine may increase sensitivity to sunlight; take precautions against sun exposure.
• Children: Not recommended for use in children below 18 years of age, unless specifically prescribed by a doctor with caution.

Storage Store BRUTACEF O TAB at room temperature (20-25°C) and protect it from direct sunlight, heat, and moisture. Keep it in its original container, tightly closed, and out of the sight and reach of children and pets.

What is Brutacef O Tablet used for?

Brutacef O Tablet is a combination antibiotic primarily used to treat a wide range of bacterial infections. It is effective against various conditions, including bacterial infections of the skin, ears, lungs, prostate, and urinary tract. It also treats typhoid fever and sexually transmitted diseases (STDs) like chlamydia and gonorrhea, as well as respiratory tract infections such as community-acquired pneumonia, acute exacerbations of chronic bronchitis, tonsillitis, and pharyngitis.

How does Brutacef O Tablet work?

Brutacef O Tablet contains two active ingredients: Cefixime and Ofloxacin. Cefixime is a cephalosporin antibiotic that prevents the formation of the bacterial cell wall, which is essential for the bacteria's survival. Ofloxacin is a fluoroquinolone antibiotic that works by inhibiting bacterial enzymes, such as DNA gyrase and topoisomerase IV, which are necessary for bacteria to reproduce and repair themselves. The combined action of these two antibiotics effectively kills the bacteria (bactericidal action) and stops their growth.

What is the usual dosage of Brutacef O Tablet?

The usual dosage of Brutacef O Tablet, typically containing Cefixime 200 mg and Ofloxacin 200 mg, should be taken as prescribed by your doctor. Your doctor will determine the frequency and duration of the dose based on your medical condition and response to treatment. It can be taken with or without food, but it's recommended to take it at a fixed time for optimal results. It is crucial to complete the entire course of treatment, even if symptoms improve, to prevent antibiotic resistance.

What are the possible side effects of Brutacef O Tablet?

Common side effects of Brutacef O Tablet may include nausea, vomiting, diarrhea, indigestion, loose stools, and abdominal pain. Other possible side effects can include headache, dizziness, decreased appetite, and a change in taste. Some individuals may experience skin reactions like rash or itching. If any side effects worsen or persist, it is advisable to consult your doctor.

Is Brutacef O Tablet safe during pregnancy or breastfeeding?

Brutacef O Tablet is generally not recommended during pregnancy as there is limited safety information available, and Ofloxacin, one of its components, may affect the developing joints of the fetus. Similarly, it is advisable not to breastfeed while taking this medicine as a component may pass into breast milk and could be harmful to the infant's joint growth. The use of Brutacef O Tablet during pregnancy or breastfeeding is only allowed if clearly suggested by a doctor, who will weigh the potential benefits against the risks.

Can Brutacef O Tablet be taken with other medications?

Brutacef O Tablet can interact with certain medications. It is important to inform your doctor about all medicines, supplements, or herbal products you are currently taking to avoid possible interactions. For instance, antacids and iron supplements can reduce the absorption of Cefixime and Ofloxacin, so Brutacef O Tablet should be taken at least two hours before them. It may also interact with blood thinners, other antibiotics, medicines for heart problems, mental health issues, fits, diabetes, asthma, and anti-HIV drugs. Taking it with corticosteroids may increase the risk of tendon rupture.

What precautions should be taken while taking Brutacef O Tablet?

Several precautions should be taken with Brutacef O Tablet. Avoid consuming dairy products like milk, as they can interfere with the absorption of Ofloxacin. Limit alcohol consumption as it may worsen side effects such as dizziness. This medicine may cause dizziness, confusion, or affect vision, so caution is advised when driving or operating machinery. Inform your doctor if you have a history of kidney or liver diseases, seizure disorders, tendinitis, myasthenia gravis, or bleeding disorders. It is generally not recommended for children below 18 years of age.

What happens if a dose of Brutacef O Tablet is missed?

If you miss a dose of Brutacef O Tablet, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed one, as this may lead to an overdose.

How should Brutacef O Tablet be stored?

Brutacef O Tablet should be stored below 25°C in a cool and dry place, protected from direct sunlight, heat, and moisture. Keep the medicine out of the sight and reach of children and pets. Ensure that unused medicine is disposed of properly and not used after its expiry date.