Teneza-m 500tablet

TENEZA-M 500 TABLET

TENEZA-M 500 Tablet is an oral antidiabetic medication manufactured by Torrent Pharmaceuticals Ltd., designed to manage Type 2 diabetes mellitus in adults.

Composition Each tablet contains:

• Teneligliptin: 20 mg
• Metformin Hydrochloride: 500 mg

Uses TENEZA-M 500 Tablet is prescribed for the management of Type 2 diabetes mellitus in adults. It is used when diet and exercise alone, or metformin monotherapy, are not sufficient to achieve adequate glycemic control. This medication works by decreasing liver glucose production, lowering intestinal glucose absorption, and increasing insulin levels in the body, thereby improving insulin sensitivity and controlling both fasting and post-meal blood sugar levels.

Dosage and Administration The typical adult dosage is one tablet, taken orally once or twice daily, preferably with meals to reduce gastrointestinal side effects. Tablets should be swallowed whole and not broken, crushed, or chewed. The dosage may be adjusted by a healthcare professional based on the patient's condition and blood sugar levels.

Side Effects Common side effects may include:

• Nausea, vomiting, diarrhea
• Headache, stomach ache, abdominal discomfort
• Hypoglycemia (low blood sugar), especially when combined with insulin or sulfonylureas
• Respiratory tract infection, weight gain, sweating

A rare but serious side effect is lactic acidosis, characterized by muscle pain, fatigue, dizziness, difficulty breathing, and stomach pain.

Precautions TENEZA-M 500 Tablet is contraindicated in patients with severe kidney impairment, liver impairment, congestive heart failure, lactic acidosis, or diabetic ketoacidosis. Alcohol consumption should be avoided due to an increased risk of lactic acidosis. Use during pregnancy and breastfeeding is generally not recommended, and a doctor should be consulted. Regular monitoring of blood sugar and kidney function is advised.

Storage Store the medicine below 25°C or 30°C, in a cool and dry place, protected from direct sunlight, heat, and moisture. Keep it out of the sight and reach of children.

Here are frequently asked questions about TENEZA-M 500TABLET:

What is Teneza-M 500 Tablet used for?

Teneza-M 500 Tablet is primarily used to manage type 2 diabetes mellitus in adults. It helps improve glycemic control when diet and exercise alone are not sufficient. This medication is a combination of two active ingredients that work together to lower high blood sugar levels.

How does Teneza-M 500 Tablet work?

Teneza-M 500 Tablet contains Metformin and Teneligliptin. Metformin, a biguanide, works by reducing the production of glucose in the liver, decreasing the absorption of glucose from the intestines, and enhancing the body's sensitivity to insulin. Teneligliptin, a dipeptidyl peptidase-4 (DPP-4) inhibitor, increases insulin secretion from the pancreas and reduces the levels of hormones that raise blood sugar, especially after meals. This combined action helps in better control of blood sugar levels.

What is the usual dosage of Teneza-M 500 Tablet?

The daily dose of Teneza-M 500 Tablet should be taken as directed by your doctor. It is recommended to take this medicine with food to help reduce stomach upset. The tablet should be swallowed whole with a glass of water and not crushed, chewed, or broken. Your doctor will determine the correct dose and duration of therapy based on your age, body weight, and medical condition.

What are the possible side effects of Teneza-M 500 Tablet?

Common side effects may include diarrhea, nausea or vomiting, headache, and stomach upset. A more serious but rare side effect is lactic acidosis, a build-up of acid in the body, which can cause symptoms like weakness, tiredness, fast breathing, muscle pain, dizziness, and stomach pain. Long-term use of metformin, one of the components, may also lead to Vitamin B12 deficiency. If you experience persistent or severe side effects, consult your doctor.

Is Teneza-M 500 Tablet safe during pregnancy or breastfeeding?

Caution is advised if you are pregnant, and it is crucial to consult your doctor before taking Teneza-M 500 Tablet, as the potential benefits must outweigh any risks to the fetus. For breastfeeding mothers, Teneza-M 500 Tablet is generally not recommended as metformin is present in human milk, and its effects on the breastfed infant are unknown. Your doctor will guide you on whether to discontinue nursing or the medicine.

Can it be taken with other medications?

Teneza-M 500 Tablet can interact with certain other medications. For example, carbonic anhydrase inhibitors (like acetazolamide) or medicines that reduce metformin clearance (such as ranolazine, vandetanib, dolutegravir, and cimetidine) may increase the risk of lactic acidosis or metformin accumulation. It is important to inform your doctor about all medicines, including herbal preparations and supplements, you are taking to avoid potential interactions.

What precautions should be taken?

Teneza-M 500 Tablet should be used with caution or avoided in certain conditions. It is contraindicated in severe renal impairment, metabolic acidosis (including diabetic ketoacidosis), and known hypersensitivity to metformin or teneligliptin. Exercise caution if you have liver disease, heart problems, severe infections, or are elderly. Excessive alcohol intake should be avoided as it can increase the risk of lactic acidosis. The safety and effectiveness in children have not been established.

What happens if a dose is missed?

If you miss a dose of Teneza-M 500 Tablet, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed one.

How should it be stored?

Teneza-M 500 Tablet should be stored in a cool and dry place, protected from direct sunlight, moisture, and heat. Keep it out of the sight and reach of children. The storage temperature should generally be below 25°C or 30°C.