Clofert 25 Mg Tablet (30 Tab)

CLOFERT 25 MG TABLET (30 TAB) by MANEESH PHARMACEUTICALS LTD.

CLOFERT 25 MG TABLET is a medication primarily used to address infertility in both men and women, functioning as an ovulation stimulant. It is manufactured by Maneesh Pharmaceuticals Ltd.

Composition

• Active Ingredient: Clomiphene Citrate 25 mg (also referred to as Clomiphene).

Uses

CLOFERT 25 MG TABLET is prescribed for:

• Female Infertility: It is primarily used to treat female infertility, especially in women experiencing difficulties conceiving due to ovulation problems (anovulatory infertility) or conditions like Polycystic Ovary Syndrome (PCOS). It works by stimulating the hormones necessary for the development and release of mature eggs from the ovaries.
• Male Infertility: In men, it helps by boosting hormone production, thereby increasing sperm production and enhancing overall fertility.

Dosage and Administration

• Administration: The tablet should be swallowed whole with a glass of water, and not chewed, crushed, or broken.
• Timing: It can be taken with or without food. To maximize effectiveness, it is recommended to take it at the same time each day.
• Guidance: Adhere strictly to the prescribed schedule and dosage given by your doctor. It is typically taken once daily for 5 days, often starting on the 5th day of your menstrual period, or as per your doctor's specific instructions. Your doctor may monitor your progress and adjust the dosage if needed.

Side Effects

While generally well-tolerated, some individuals may experience side effects:

• Common Side Effects: Headache, dizziness, breast pain or tenderness (including breast enlargement in males), hot flushes (vasomotor flushing), enlarged ovaries (potentially causing lower abdominal or pelvic pain), gastrointestinal disturbances (nausea, vomiting, bloating), tiredness, heavy periods, bleeding between periods, and visual disturbances such as blurred vision or seeing spots/flashes.
• Serious Side Effects: Seek immediate medical attention if you experience signs of Ovarian Hyperstimulation Syndrome (OHSS) (e.g., severe lower abdominal pain with nausea/vomiting, weight gain, difficulty breathing) or signs of allergic reactions (e.g., skin rash, swelling of the eyes, face, lips, tongue or throat).

Precautions

• Contraindications: Do not take CLOFERT 25 MG TABLET if you are allergic to Clomiphene Citrate, have liver disease, unexplained vaginal bleeding, certain hormone-dependent cancers, ovarian cysts (not related to PCOS), a pituitary gland tumor, active thyroid or adrenal gland conditions, or early menopause. It is not recommended for pregnant women (classified as a Category X drug due to potential harm to the fetus), breastfeeding women (may decrease breast milk supply), children, adolescents, or post-menopausal women.
• Warnings: Exercise caution when driving or operating heavy machinery, as the medication can cause dizziness and vision problems. Inform your doctor about all other medications you are taking, including over-the-counter and herbal products, to prevent potential drug interactions (e.g., with estrogens, progestins, certain cancer medications like letrozole or anastrozole, and NSAIDs). Use with caution if you have uterine fibroids, endometriosis, high blood fat levels, or a history of fits. Regular monitoring by your doctor, including blood tests and ultrasounds, is crucial during treatment. Avoid alcohol consumption.

Storage

• Store CLOFERT 25 MG TABLET in a cool and dry place, away from direct sunlight, at a temperature below 30°C or 25°C.
• Keep out of sight and reach of children.

Here are frequently asked questions about CLOFERT 25 MG Tablet:

What is CLOFERT 25 MG Tablet used for?

CLOFERT 25 MG Tablet is primarily used to treat infertility in both women and men. In women, it helps address difficulties in becoming pregnant by enhancing ovulation (the release of a mature egg from the ovary), often in cases of ovulatory dysfunction or Polycystic Ovary Syndrome (PCOS). For men, it is used to improve hormone production, which can lead to increased sperm production and enhanced fertility.

How does CLOFERT 25 MG Tablet work?

CLOFERT 25 MG Tablet contains Clomifene Citrate, which acts as an ovulation stimulant. It works by mimicking the action of estrogen and stimulating the pituitary gland to release higher levels of follicle-stimulating hormone (FSH) and luteinizing hormone (LH). These hormones are essential for the growth and maturation of eggs in women and for the production of testosterone and sperm in men, thereby promoting fertility.

What is the usual dosage of CLOFERT 25 MG Tablet?

For female infertility due to anovulation, the typical adult dosage is 50 mg (two 25 mg tablets) once daily for 5 days. This course usually starts on the 5th day of the menstrual period. If ovulation does not occur, a second course of 100 mg (four 25 mg tablets) for 5 days may be initiated, starting as early as 30 days after the previous therapy. It should be taken at the same time each day, with or without food, and swallowed whole without chewing or crushing. Your doctor will determine the exact dose and duration based on your condition.

What are the possible side effects of CLOFERT 25 MG Tablet?

Common side effects can include flushing (hot flashes), headache, dizziness, breast pain or tenderness (and breast enlargement in males), enlarged ovaries, abdominal pain, bloating or discomfort, nausea, vomiting, tiredness, heavy periods, bleeding between periods, and vision problems such as blurred vision or visual spots/flashes. These side effects often subside as your body adjusts to the medication, but if they persist or worsen, you should consult your doctor.

Is CLOFERT 25 MG Tablet safe during pregnancy or breastfeeding?

CLOFERT 25 MG Tablet is considered unsafe and contraindicated during pregnancy (categorized as a Category X drug) as it may cause birth defects. A negative pregnancy test must be confirmed before starting treatment. It is also not recommended for use during breastfeeding as it may decrease the supply of breast milk. You should consult your doctor if you are pregnant, planning to conceive, or breastfeeding.

Can CLOFERT 25 MG Tablet be taken with other medications?

Caution is advised when taking CLOFERT 25 MG Tablet with other medications. It may interact with estrogens and progestins, potentially reducing its effectiveness. Certain cancer medications (e.g., letrozole, anastrozole) and non-steroidal anti-inflammatory drugs (NSAIDs) like ibuprofen may also interfere with its action. Always inform your doctor about all prescription, non-prescription, and herbal medicines you are currently taking to prevent potential drug interactions.

What precautions should be taken while using CLOFERT 25 MG Tablet?

You should not take CLOFERT 25 MG Tablet if you are allergic to clomifene, have liver disease, unexplained abnormal uterine bleeding, a hormone-dependent tumor, or an ovarian cyst. Special caution is needed if you have polycystic ovaries, uterine fibroids, kidney problems, high blood fat levels (hyperlipidaemia), or a history of fits. Since the medicine may cause dizziness or visual disturbances, it is important to avoid driving or operating heavy machinery until you understand how it affects you. Alcohol consumption may also worsen your condition and increase the risk of side effects.

What happens if a dose of CLOFERT 25 MG Tablet is missed?

If you miss a dose of CLOFERT 25 MG Tablet, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed one.

How should CLOFERT 25 MG Tablet be stored?

CLOFERT 25 MG Tablet should be stored in a cool, dry place, typically below 25°C or 30°C. Keep it away from direct sunlight and out of the sight and reach of children.