Zilsar 40

ZILSAR 40 Tablet

Name

• Brand Name: ZILSAR 40
• Common Name: Azilsartan medoxomil (active ingredient)

Composition ZILSAR 40 contains Azilsartan medoxomil 40 mg as its active ingredient.

Uses ZILSAR 40 is prescribed for the treatment of:

• Hypertension (high blood pressure)
• Heart failure
• Prevention of heart attack and stroke
• Preserving kidney function in patients with diabetes

Dosage and Administration ZILSAR 40 is typically taken orally once a day. It can be consumed with or without food. The tablet should be swallowed whole with a glass of water and not chewed, crushed, or broken. For optimal benefit, it is recommended to take the medicine at the same time each day. Do not stop taking ZILSAR 40 abruptly without consulting your doctor, as this may worsen your condition. For hypertension, a usual adult dose is 80 mg once a day, with a starting dose of 40 mg once daily considered for patients on high diuretic doses.

Side Effects Common side effects include dizziness, diarrhea, low blood pressure, nausea, muscle spasms, skin rash, and itching. If you experience severe, persistent diarrhea and substantial weight loss, seek immediate medical attention. Overdosing may lead to a significant decrease in blood pressure, causing dizziness or fainting.

Precautions ZILSAR 40 is contraindicated if you are allergic to azilsartan or any of its ingredients, are pregnant (especially in the second and third trimesters), or have diabetes or kidney disorders and are concurrently taking aliskiren. Caution is advised in patients with severe liver disease, and dose adjustment may be necessary. Inform your doctor if you have underlying kidney disease for regular monitoring of kidney function. Avoid or limit alcohol consumption during treatment as it may exacerbate low blood pressure and cause dizziness or drowsiness. Due to the potential for dizziness, exercise caution when driving or operating machinery. This medicine is not recommended for children and adolescents under 18 years of age.

Storage Store ZILSAR 40 below 30°C and protect it from light and moisture. Keep the container tightly closed and out of the reach of children. Always check the expiry date before use.

Here are some frequently asked questions about ZILSAR 40 (Azilsartan medoxomil 40mg) by Torrent Pharmaceuticals Ltd, along with concise answers:

What is ZILSAR 40 used for?

ZILSAR 40 is primarily used to treat high blood pressure (hypertension) and heart failure. It also helps in preventing future heart attacks and strokes, and is effective in preserving kidney function in patients with diabetes.

How does ZILSAR 40 work?

ZILSAR 40 contains Azilsartan medoxomil, which belongs to a class of medicines called angiotensin receptor blockers (ARBs). It works by blocking the action of a natural chemical in the body called angiotensin II, which normally causes blood vessels to narrow. By blocking this action, ZILSAR 40 relaxes and widens the blood vessels, allowing blood to flow more smoothly and lowering blood pressure.

What is the usual dosage for ZILSAR 40?

The usual dosage of ZILSAR 40 is one tablet taken once daily, or as advised by your doctor. It can be taken with or without food, but it's recommended to take it at the same time each day to get the most benefit and for consistency. The tablet should be swallowed whole with water and not chewed, crushed, or broken. Your doctor will determine the appropriate dose and duration of treatment based on your condition.

What are the possible side effects of ZILSAR 40?

Common side effects of ZILSAR 40 include dizziness, headache, diarrhea, low blood pressure, nausea, fatigue, muscle spasms, skin rash, and itching. Dizziness is particularly common, especially after the first dose. If these side effects bother you or do not go away, consult your doctor. In rare cases, severe side effects like difficulty breathing, severe allergic reactions, or kidney issues may occur, requiring immediate medical attention.

Is ZILSAR 40 safe during pregnancy or breastfeeding?

Pregnancy: ZILSAR 40 is unsafe and not recommended during pregnancy, especially during the second and third trimesters, as there is definite evidence of risk to the developing baby. If you become pregnant while taking this medicine, discontinue it as soon as possible and consult your doctor. Breastfeeding: ZILSAR 40 is probably unsafe and not recommended for use during breastfeeding due to potential risk to the nursing infant. Consult your doctor for safer alternative treatments if you are breastfeeding.

Can ZILSAR 40 be taken with other medications?

It is crucial to inform your doctor about all prescription, over-the-counter medications, and herbal supplements you are currently taking to avoid potential drug interactions. ZILSAR 40 may interact with certain medications, including:

• Potassium-sparing diuretics (e.g., spironolactone, amiloride), potassium supplements, or salt substitutes containing potassium, as these can increase potassium levels in the blood (hyperkalemia).
• Angiotensin-converting enzyme (ACE) inhibitors (e.g., enalapril, lisinopril), which may increase the risk of very low blood pressure and high potassium levels.
• Non-steroidal anti-inflammatory drugs (NSAIDs) (e.g., ibuprofen) can reduce the effectiveness of ZILSAR 40 and increase the risk of kidney problems.
• Lithium (used for mental health problems) can have its blood levels increased, potentially leading to toxicity.
• Aliskiren (another blood pressure-lowering medicine) is contraindicated, especially in patients with diabetes or impaired kidney function.
• Heparin.
• Some decongestants used for common cold or allergies.

What precautions should be taken while taking ZILSAR 40?

Do not stop taking ZILSAR 40 suddenly without consulting your doctor, as this could worsen your condition. As ZILSAR 40 may cause dizziness or weakness, especially when starting treatment, rise slowly if you have been sitting or lying down. Exercise caution when driving or operating heavy machinery. It is advised to avoid or limit alcohol consumption as it may increase side effects like dizziness or drowsiness. Inform your doctor if you have any pre-existing kidney or liver problems, heart conditions, diabetes, low blood pressure, or high potassium levels in your blood. Regular monitoring of kidney function, blood pressure, and potassium levels may be necessary during treatment. ZILSAR 40 is not recommended for children and adolescents under 18 years of age.

What happens if a dose of ZILSAR 40 is missed?

If you forget to take a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.

How should ZILSAR 40 be stored?

Store ZILSAR 40 below 30°C. Keep it in a cool, dry place, protected from light and moisture, and ensure the container is tightly closed. Always keep this medicine out of the reach of children. Remember to check the expiry date before taking the tablet.