Mebiz Sr Capsule (10 Cap)

MEBIZ SR CAPSULE (10 CAP) by SUN PHARMA LABORATORIES LTD.

Name

• Brand Name: Mebiz SR Capsule
• Common Name: Mebeverine Sustained Release Capsule

Composition

• Active Ingredient: Mebeverine Hydrochloride (200 mg sustained release)

Uses

Mebiz SR Capsule is an antispasmodic medication primarily used to treat symptoms associated with Irritable Bowel Syndrome (IBS) and related gastrointestinal disorders. It helps to relieve:

• Stomach pain and cramps
• Abdominal spasms
• Bloating and gas formation
• Changes in bowel habits, including spastic constipation, mucous colitis, and persistent non-specific diarrhea The active ingredient, Mebeverine, works by relaxing the smooth muscles of the intestine, thereby reducing painful contractions.

Dosage and Administration

• Typical Dosage: For adults, elderly, and children over 10 years, the usual dose is one 200 mg capsule twice daily.
• Administration: It is most effective when taken orally about 20 minutes before meals.
• Swallow the capsule whole with a glass of water. Do not chew, crush, or break it.
• Do not exceed the prescribed dose. If a dose is missed, take it as soon as possible, but skip it if it is almost time for the next dose; do not double the dose.

Side Effects

While generally well-tolerated, some individuals may experience side effects:

• Common: Skin rash
• Serious (seek immediate medical attention if experienced): Allergic reactions such as fainting, angioedema (swelling of deeper skin layers), urticaria, difficulty breathing, or swelling of the face, neck, lips, or tongue.

Precautions

• Inform your doctor if you have known allergies to Mebeverine or any other ingredients in the capsule.
• Consult a doctor if you are pregnant or breastfeeding.
• Use with caution and inform your doctor if you have a history of porphyria, heart disease, kidney disease, liver problems, or severe constipation.
• Not recommended for children under 10 years of age.
• Alcohol interaction is unknown; consult your doctor before consuming alcohol while on this medication.
• It generally does not affect the ability to drive or operate machinery, but avoid such activities if you experience dizziness.
• Inform your doctor about all other medications, including prescription, non-prescription, vitamins, and herbal supplements, to avoid potential interactions.

Storage

• Store in a cool and dry place.
• Keep away from direct sunlight.
• Keep out of sight and reach of children.
• Do not store above 30°C.

Here are the frequently asked questions about MEBIZ SR CAPSULE:

What is MEBIZ SR CAPSULE used for?

MEBIZ SR CAPSULE is primarily used to treat and relieve symptoms of Irritable Bowel Syndrome (IBS). These symptoms include abdominal pain and spasms, cramps in the abdomen, gas, bloating, chronic irritable colon, spastic constipation, mucous colitis, and changes in bowel habits like diarrhea alternating with constipation. It can also aid in managing abdominal or stomach spasms and symptoms of inflammatory bowel disease (IBD).

How does MEBIZ SR CAPSULE work?

The active ingredient in MEBIZ SR CAPSULE is Mebeverine, which is an antispasmodic agent. It works by directly relaxing the smooth muscles of the gastrointestinal tract, particularly those in the abdomen and intestines. This action helps to reduce painful spasms and contractions without affecting the normal movement of the gut. Mebeverine influences calcium channels and muscarinic receptors on smooth muscle, thereby interrupting pain sensations.

What is the usual dosage for MEBIZ SR CAPSULE?

For adults, elderly, and children over 10 years, the usual dosage for MEBIZ SR 200 mg capsule is one capsule twice daily. It is most effective when taken orally with water approximately 20 minutes before meals. The capsule should be swallowed whole and not chewed, crushed, or broken. Your doctor will provide specific guidance on dosage and treatment duration based on your condition.

What are the possible side effects of MEBIZ SR CAPSULE?

While generally well-tolerated, some possible side effects of MEBIZ SR CAPSULE include skin rash, fainting, urticaria (hives), angioedema (swelling of deeper skin layers, especially of the face, lips, tongue, or throat), and other allergic reactions like itching. Less common side effects reported are headache, dizziness, nausea, vomiting, and muscle cramps. If you experience serious side effects like difficulty breathing or significant swelling, discontinue the medication and seek immediate medical attention.

Is MEBIZ SR CAPSULE safe during pregnancy or breastfeeding?

Pregnancy: MEBIZ SR CAPSULE is generally not recommended during pregnancy unless considered absolutely necessary and specifically advised by a doctor. While animal studies have not shown teratogenicity, it's advised to exercise usual precautions regarding any drug administration during pregnancy.

Breastfeeding: Limited information is available regarding the use of MEBIZ SR CAPSULE during breastfeeding. It is advisable to consult your doctor before taking this medicine if you are breastfeeding. Although Mebeverine does not appear to excrete into breast milk at therapeutic doses, some sources suggest it is probably unsafe or that avoidance is recommended.

Can MEBIZ SR CAPSULE be taken with other medications?

It is important to inform your doctor about all prescription and non-prescription medications, vitamins, and herbal supplements you are currently taking, as some may interact with MEBIZ SR CAPSULE. Specific medications that may interact include Orlistat and Mefloquine. However, MEBIZ SR CAPSULE does not affect contraceptive pills.

What precautions should be taken while taking MEBIZ SR CAPSULE?

Do not take MEBIZ SR CAPSULE if you are allergic to Mebeverine or any of its ingredients. Inform your doctor if you have a history of acute porphyria, heart disease, kidney disease, liver issues, or severe constipation. Caution is advised if you are 40 years of age or above, or if you experience symptoms like blood in stool, loss of appetite, food poisoning, abnormal vaginal bleeding or discharge, fever, or if you are very constipated, feeling tired, pale, or sick. The medicine contains lactose, so inform your doctor if you have a sugar intolerance. It is not recommended for children under 10 years of age. Also, do not stop taking the capsules without consulting your doctor, even if your symptoms improve.

What happens if a dose of MEBIZ SR CAPSULE is missed?

If you miss a dose of MEBIZ SR CAPSULE, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to compensate for the missed one.

How should MEBIZ SR CAPSULE be stored?

MEBIZ SR CAPSULE should be stored below 30°C in a cool and dry place. Keep it away from direct heat and sunlight, and ensure it is kept out of the sight and reach of children. It should be stored in its original package to protect it from moisture.