Ozomet Pg 1 Tab

OZOMET PG 1 Tablet

OZOMET PG 1 Tablet is a combination medication manufactured by Ozone Pharmaceuticals Ltd., primarily prescribed for the management of Type 2 Diabetes Mellitus in adults. It is used when blood sugar levels are not adequately controlled by diet and exercise alone, or by single-agent therapy.

Composition Each tablet contains a blend of three active antidiabetic agents:

• Glimepiride (1mg): A sulfonylurea that stimulates the pancreas to produce more insulin, thereby lowering blood sugar.
• Metformin (500mg): A biguanide that reduces glucose production in the liver, delays sugar absorption from the intestines, and enhances the body's sensitivity to insulin.
• Pioglitazone (15mg): A thiazolidinedione that increases the sensitivity of liver, muscle, and fat cells to insulin, allowing for more effective glucose removal from the blood.

Uses OZOMET PG 1 Tablet is indicated for the treatment of Type 2 Diabetes Mellitus. It helps to control high blood sugar levels, improve insulin utilization, and prevent complications associated with diabetes such as nerve problems, kidney problems, eye problems, and cardiovascular disease.

Dosage and Administration This medicine should be taken orally, once daily, preferably with food to minimize stomach upset, or as advised by your doctor. The tablet should be swallowed whole and not crushed or chewed. Your doctor will determine the appropriate dose and duration of therapy based on your age, body weight, and medical condition.

Side Effects Common side effects may include:

• Stomach pain, nausea, diarrhea, vomiting
• Headache
• Metallic taste
• Hypoglycemia (low blood sugar)
• Edema (swelling)
• Weight gain
• Upper respiratory tract infection
• Blurred vision

Serious side effects, particularly with overdose, can include loss of consciousness, lactic acidosis (accumulation of lactic acid in the body), and pancreatitis (inflammation of the pancreas).

Precautions

• Pregnancy and Breastfeeding: Not recommended during pregnancy as it may harm the unborn baby. It is also probably unsafe during breastfeeding, as it may be excreted in human milk. Consult your doctor if you are pregnant, planning pregnancy, or breastfeeding.
• Alcohol: Avoid alcohol consumption as it may increase the risk of lactic acidosis.
• Driving: Exercise caution, as hypoglycemia can affect alertness and ability to drive or operate machinery.
• Medical Conditions: Inform your doctor if you have kidney, liver, or heart problems, congestive heart failure, eye problems, hormonal imbalance, or if you are malnourished, starved, or on an irregular diet. Use with caution in elderly patients.
• Drug Interactions: Inform your doctor about all other medications, supplements, and herbal products you are taking.
• Contraindications: Not recommended for children, patients with Type 1 Diabetes Mellitus, diabetic ketoacidosis, bladder cancer, or severe heart failure.

Storage Store OZOMET PG 1 Tablet in a cool and dry place, away from direct sunlight, at room temperature (between 10°C and 25°C or below 30°C). Keep it out of the reach and sight of children and pets.

OZOMET PG 1 TAB is a combination medication used to manage Type 2 Diabetes Mellitus. It contains Glimepiride, Metformin, and Pioglitazone, which work together to help control blood sugar levels when diet, exercise, and other treatments are insufficient.

What is OZOMET PG 1 TAB used for?

OZOMET PG 1 TAB is used to treat Type 2 Diabetes Mellitus in adults, particularly when blood sugar levels are not adequately controlled by diet and exercise alone, or with single or dual antidiabetic therapies. It helps lower high blood glucose (sugar) levels and reduce the risk of diabetes-related complications such as nerve problems, kidney problems, eye problems, and cardiovascular disease.

How does OZOMET PG 1 TAB work?

This medicine works through the combined action of its three active ingredients:

• Glimepiride: Stimulates the pancreas to produce and release more insulin, which helps move sugar from the blood into cells.
• Metformin: Reduces the production of sugar by the liver, delays the absorption of sugar from the intestines, and increases the body's sensitivity to insulin.
• Pioglitazone: Increases the sensitivity of liver, muscle, and fat cells to insulin, allowing them to remove glucose from the blood more effectively.

What is the usual dosage for OZOMET PG 1 TAB?

The dosage of OZOMET PG 1 TAB should be taken exactly as prescribed by your physician. It is typically taken once daily with food, preferably after meals, to minimize stomach upset. The specific dose and duration of therapy will depend on your age, body weight, and medical condition. The tablet usually contains Glimepiride 1mg, Metformin 500mg, and Pioglitazone 15mg.

What are the possible side effects of OZOMET PG 1 TAB?

Common side effects may include stomach pain, nausea, diarrhea, vomiting, headache, metallic taste, low blood sugar (hypoglycemia), constipation, sore throat, muscle pain, dizziness, weight gain, and fluid retention (edema). Most common side effects usually resolve over time. However, more serious side effects like lactic acidosis or symptoms of heart failure require immediate medical attention.

Is OZOMET PG 1 TAB safe during pregnancy or breastfeeding?

Pregnancy: OZOMET PG 1 TAB is generally not recommended for use during pregnancy as it may harm the unborn baby. If you are pregnant or planning a pregnancy, consult your doctor to discuss alternative treatment options. Breastfeeding: It is also not recommended during breastfeeding as it may be excreted in human milk and could have adverse effects on the baby. It is advisable to consult your doctor for safe alternatives while breastfeeding.

Can OZOMET PG 1 TAB be taken with other medications?

You should inform your doctor about all prescription, over-the-counter medicines, supplements, and herbal products you are taking. OZOMET PG 1 TAB can interact with various medications, including other antidiabetic drugs, certain pain relievers (NSAIDs), antibiotics, antifungals, blood thinners (anticoagulants like warfarin), and certain medications for high blood pressure. Interactions could increase the risk of side effects or affect the medicine's effectiveness.

What precautions should be taken while using OZOMET PG 1 TAB?

Several precautions should be observed:

• Allergies: Do not take if you are allergic to Glimepiride, Metformin, Pioglitazone, or any other ingredients.
• Children: It is not recommended for children.
• Elderly Patients: Use with caution in elderly patients.
• Alcohol: Avoid or limit alcohol consumption as it can increase the risk of a serious condition called lactic acidosis.
• Underlying Conditions: Inform your doctor if you have kidney disease, liver disease, heart problems (e.g., congestive heart failure), bladder cancer, eye problems, hormonal imbalances, or a history of alcoholism.
• Driving: Be cautious when driving or operating machinery, as changes in blood sugar levels (especially hypoglycemia) can affect your alertness.
• Monitoring: Regular monitoring of blood sugar levels is crucial.

What happens if a dose of OZOMET PG 1 TAB is missed?

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed one.

How should OZOMET PG 1 TAB be stored?

Store OZOMET PG 1 TAB at room temperature, typically between 10°C to 25°C or below 30°C, in a cool, dry place. Protect it from light and moisture. Always keep the medicine out of the reach and sight of children and pets.