Sacu V 100 Tablet

Here is a detailed product description for SACU V 100 TABLET:

SACU V 100 TABLET

Name

• Brand Name: Sacu-V 100 Tablet
• Common Name: Sacubitril and Valsartan

Composition SACU V 100 Tablet is a fixed-dose combination medicine containing Sacubitril 49 mg and Valsartan 51 mg.

Uses SACU V 100 Tablet is primarily used for the treatment of chronic heart failure with reduced ejection fraction in adults. It helps to reduce the risk of cardiovascular death and hospitalization for heart failure. It works by relaxing and widening blood vessels, making it easier for the heart to pump blood throughout the body. The medication may also be used to manage hypertension (high blood pressure) and provide cardiovascular protection. It is also indicated for use in children above one year of age for heart failure treatment.

Dosage and Administration Take SACU V 100 Tablet exactly as prescribed by your doctor. The dosage and duration of treatment are determined based on your medical condition and response to therapy. It can be taken with or without food, preferably at the same time each day, for maximum benefits. Do not chew, crush, or break the tablet; swallow it whole with a glass of water. Do not stop taking this medicine abruptly without consulting your doctor, even if you feel better.

Side Effects Common side effects may include:

• Dizziness, light-headedness (low blood pressure)
• Cough
• Nausea
• Diarrhea
• Weakness, fatigue
• Headache
• Increased potassium levels in the blood (hyperkalemia)
• Impaired kidney function or increased creatinine levels
• Stomach pain or inflammation of the lining of the stomach

Serious side effects, though rare, can include severe allergic reactions such as angioedema (swelling of the face, lips, tongue, or throat), which may cause difficulty breathing or swallowing. Seek immediate medical attention if these occur.

Precautions

• Contraindications: SACU V 100 Tablet is contraindicated during pregnancy as it may cause harm to the developing fetus. It is also not recommended for use in breastfeeding women. Do not take this medicine if you are allergic to Sacubitril, Valsartan, or any of its components, or if you have a history of angioedema. It should not be used in combination with ACE inhibitors or within 36 hours before or after taking an ACE inhibitor drug. Not suitable for children and adolescents under 18 years of age.
• Warnings: Inform your doctor if you have kidney or liver diseases, as dose adjustments may be needed and caution is advised. Patients should rise slowly from a sitting or lying position to prevent orthostatic hypotension (sudden drop in blood pressure). Regular monitoring of blood pressure, kidney function, and potassium levels is recommended during treatment.
• Drug Interactions: Avoid co-administration with ACE inhibitors, Aliskiren, and other angiotensin receptor blockers. Caution is advised with potassium supplements, potassium-sparing diuretics (e.g., spironolactone), NSAIDs (e.g., ibuprofen), lithium, sildenafil, heparin, and warfarin.
• Alcohol: It is advisable to avoid consuming alcohol as it may increase the risk of side effects such as dizziness and low blood pressure.

Storage Store SACU V 100 Tablet in a cool and dry place, away from direct sunlight and moisture, ideally below 30°C. Keep the medicine out of the sight and reach of children.

SACU V 100 Tablet is a medication manufactured by Glenmark Pharmaceuticals Ltd. and is a combination of Sacubitril (49mg) and Valsartan (51mg). It is primarily used to treat heart failure.

Here are some frequently asked questions about SACU V 100 Tablet:

What is SACU V 100 Tablet used for?

SACU V 100 Tablet is used to treat heart failure, a chronic condition where the heart is weakened and cannot pump blood effectively. It helps reduce the risk of hospitalization and death in adults with chronic heart failure. It may also help manage hypertension (high blood pressure) and provide cardiovascular protection.

How does SACU V 100 Tablet work?

SACU V 100 Tablet contains two active ingredients: Sacubitril and Valsartan. Sacubitril is a neprilysin inhibitor that increases levels of natriuretic peptides, which help relax blood vessels and reduce fluid retention. Valsartan is an angiotensin receptor blocker (ARB) that works by blocking the action of angiotensin II, a hormone that constricts blood vessels and promotes salt and water retention. Together, they relax and widen blood vessels, making it easier for the heart to pump blood, reduce strain on the heart, and help the body retain less water, thereby improving heart function and alleviating symptoms of heart failure.

What is the usual dosage of SACU V 100 Tablet?

The dosage and frequency of SACU V 100 Tablet are determined by your doctor based on your medical condition and response to the medicine. It can be taken with or without food, preferably at the same time each day for maximum benefits. It's crucial to follow your doctor's instructions and not exceed the recommended dose.

What are the possible side effects of SACU V 100 Tablet?

Common side effects include low blood pressure (hypotension), increased potassium levels in the blood (hyperkalemia), impaired kidney function, cough, dizziness, headache, fatigue, nausea, and diarrhea. If any of these side effects persist or worsen, it is advisable to seek medical advice. Serious side effects like angioedema (swelling of the face, lips, tongue, or throat) require immediate medical attention.

Is SACU V 100 Tablet safe during pregnancy or breastfeeding?

No, SACU V 100 Tablet is not recommended during pregnancy, especially after the first three months, as it can cause serious harm to the unborn baby. It is also not recommended for use while breastfeeding due to potential risks to the baby. Consult your doctor if you are pregnant, planning to conceive, or breastfeeding.

Can SACU V 100 Tablet be taken with other medications?

It is crucial to inform your doctor about all medications you are currently taking, including prescription, over-the-counter medicines, herbal supplements, and vitamins, to avoid potential drug interactions. SACU V 100 Tablet should not be taken with ACE inhibitors (e.g., enalapril, lisinopril) or within 36 hours of switching from or to an ACE inhibitor due to an increased risk of side effects like angioedema. Concomitant use with aliskiren (for diabetes or kidney disease) is also not recommended. Be cautious with potassium supplements, potassium-sparing diuretics, and NSAIDs (painkillers) as they can affect blood potassium levels or kidney function.

What precautions should be taken with SACU V 100 Tablet?

Inform your doctor if you have kidney or liver diseases, a history of angioedema, or diabetes. Regular monitoring of blood pressure and kidney function is often recommended during treatment. Rise slowly from a sitting or lying position to prevent dizziness due to low blood pressure. Avoid or limit alcohol consumption as it may increase side effects like dizziness. Do not stop taking the medicine abruptly, even if you feel better, as it may worsen your condition.

What happens if a dose of SACU V 100 Tablet is missed?

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed one.

How should SACU V 100 Tablet be stored?

Store SACU V 100 Tablet in a cool and dry place, away from direct sunlight and moisture, ideally below 30°C. Keep it out of the sight and reach of children.