Sgltd M 10/500 Mg Tablet (10 Tab)

SGLTD M 10/500 MG TABLET

SGLTD M 10/500 MG TABLET is an oral antidiabetic medication manufactured by Mankind Pharma Ltd., used for the management of type 2 diabetes mellitus.

• Composition Each tablet contains a fixed-dose combination of Dapagliflozin (10 mg) and Metformin (500 mg). Dapagliflozin is a sodium-glucose co-transporter-2 (SGLT2) inhibitor that works by removing excess sugar from the body through urine. Metformin is a biguanide that reduces glucose production in the liver, decreases intestinal absorption of glucose, and improves the body's sensitivity to insulin.

• Uses SGLTD M 10/500 MG TABLET is prescribed for adults with type 2 diabetes mellitus to:

  • Lower high blood sugar levels.
  • Improve glycemic control.
  • Prevent serious complications associated with diabetes, such as kidney damage, nerve problems, and eye damage.
  • Enhance insulin sensitivity.
  • Reduce the risk of hospitalization for heart failure in adults with type 2 diabetes and established cardiovascular disease or multiple cardiovascular risk factors. It may also be used in combination with insulin or GLP-1 receptor agonists.

• Dosage and Administration This medication should be taken orally, usually once daily in the morning, with or without food, as directed by a healthcare professional. The tablet should be swallowed whole with a glass of water and not crushed, chewed, or broken. Dosage is based on the individual's medical condition and response to treatment.

• Side Effects Common side effects may include:

  • Frequent urination.
  • Mild skin rash or itchy skin.
  • Diarrhea, stomach pain, nausea, vomiting, and loss of appetite.
  • Genital fungal infections and urinary tract infections.
  • Dehydration and low blood pressure. Serious but rare side effects include lactic acidosis (due to metformin accumulation) and ketoacidosis.

• Precautions

  • Not recommended for individuals with type 1 diabetes mellitus or severe kidney or liver disease.
  • Avoid alcohol consumption as it may increase the risk of lactic acidosis.
  • Caution is advised in elderly patients, and dose adjustments may be required based on renal function.
  • Pregnant or breastfeeding women should consult their doctor before use.
  • Inform your doctor about any history of heart disease, breathing problems, blood disorders, dehydration, or low blood pressure.
  • Interactions may occur with diuretics, insulin, insulin secretagogues, carbonic anhydrase inhibitors, and certain cationic medicines.
  • Do not stop taking the medicine abruptly without consulting a doctor.

• Storage Store in a cool and dry place, away from direct sunlight and moisture, typically below 30°C. Keep out of sight and reach of children.

Here are the most frequently asked questions about SGLTD M 10/500 MG TABLET:

What is SGLTD M 10/500 MG TABLET used for?

SGLTD M 10/500 MG TABLET is primarily used to manage type 2 diabetes mellitus in adults, especially when diet and exercise alone are not sufficient to control blood sugar levels. It also helps reduce the risk of hospitalization for heart failure in adults with type 2 diabetes who have established cardiovascular disease or multiple cardiovascular risk factors.

How does SGLTD M 10/500 MG TABLET work?

This medicine contains two active ingredients: Dapagliflozin (10 mg) and Metformin (500 mg). Dapagliflozin, an SGLT2 inhibitor, works by preventing the kidneys from reabsorbing glucose back into the bloodstream, leading to increased glucose excretion through urine and thus lowering blood sugar. Metformin, a biguanide, reduces glucose production in the liver, decreases glucose absorption from the intestines, and enhances the body's sensitivity to insulin.

What is the usual dosage for SGLTD M 10/500 MG TABLET?

The dosage is determined by your doctor based on your medical condition and response to treatment. It is typically taken orally, once or twice daily, preferably with meals to minimize stomach upset. It's crucial to follow your doctor's instructions precisely and not adjust the dosage without consulting them.

What are the possible side effects of SGLTD M 10/500 MG TABLET?

Common side effects can include dehydration, genital mycotic (yeast) infections, urinary tract infections (UTIs), low blood pressure, nausea, vomiting, diarrhea, abdominal pain, loss of appetite, headache, back pain, increased urination, changes in taste, and nasopharyngitis (common cold). More serious but less common side effects include hypoglycemia (especially when taken with other diabetes medications), ketoacidosis, and lactic acidosis.

Is SGLTD M 10/500 MG TABLET safe during pregnancy or breastfeeding?

SGLTD M 10/500 MG TABLET is generally not recommended for use during pregnancy, particularly in the second and third trimesters, unless absolutely necessary and advised by a doctor. It is also not recommended for breastfeeding women, as it may pass into breast milk. Always consult your doctor if you are pregnant, planning to become pregnant, or breastfeeding.

Can SGLTD M 10/500 MG TABLET be taken with other medications?

This medicine can interact with certain other medications. For example, diuretics may increase the risk of dehydration and low blood pressure. Combining it with insulin or insulin secretagogues can increase the risk of low blood sugar (hypoglycemia). Carbonic anhydrase inhibitors may increase the risk of lactic acidosis. It's essential to inform your doctor about all prescription, over-the-counter, and herbal medications you are currently taking to avoid potential interactions.

What precautions should be taken while using SGLTD M 10/500 MG TABLET?

Do not take this medicine if you have type 1 diabetes, severe kidney or liver disease, diabetic ketoacidosis, or are allergic to any of its components. Caution is advised with alcohol consumption as it can increase the risk of lactic acidosis. Regular monitoring of kidney function is important, and maintaining good personal hygiene can help prevent genital and urinary tract infections. This medication is for adults over 18 and generally not recommended for those 85 years or older.

What happens if a dose of SGLTD M 10/500 MG TABLET is missed?

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed one.

How should SGLTD M 10/500 MG TABLET be stored?

Store the tablets in a cool, dry place, typically below 30°C, away from direct sunlight and moisture. Keep this medicine out of sight and reach of children.