Triohale Rotacaps

TRIOHALE ROTACAPS, manufactured by Cipla Ltd., is a combination medication primarily used for the long-term management of Chronic Obstructive Pulmonary Disease (COPD) and asthma. It helps to relieve symptoms such as coughing, wheezing, shortness of breath, and chest tightness by targeting multiple aspects of these respiratory conditions.

Composition

Each TRIOHALE ROTACAP contains a blend of three active ingredients:

• Ciclesonide (400 mcg): A corticosteroid that reduces inflammation and swelling in the airways.
• Formoterol (12 mcg): A long-acting beta-agonist (LABA) bronchodilator that relaxes the muscles around the airways, widening them to make breathing easier.
• Tiotropium (18 mcg): A long-acting anticholinergic bronchodilator that further relaxes airway muscles and prevents constriction.

Uses

TRIOHALE ROTACAPS are prescribed for:

• Chronic Obstructive Pulmonary Disease (COPD): Long-term management of symptoms like breathlessness, wheezing, and cough, especially in severe cases with a history of repeated exacerbations.
• Asthma Management: To reduce inflammation and prevent asthma attacks by relaxing airway muscles.

Dosage and Administration

The recommended dosage is one TRIOHALE ROTACAP inhaled once daily using a Cipla Rotahaler or Revolizer device. This medicine is for inhalation only and should not be swallowed. It's crucial to use proper inhalation technique and to rinse the mouth with water after each use to prevent fungal infections. TRIOHALE ROTACAPS are not for immediate relief of sudden breathing problems; a rescue inhaler should be used for acute attacks.

Side Effects

Common side effects include:

• Dry mouth, dry throat, and cough.
• Headache, hoarseness of voice, and nasopharyngitis.
• Fungal infection of the oropharynx.
• Increased heart rate and palpitations.

Serious side effects may include paradoxical bronchospasm (sudden worsening of breathing), severe allergic reactions, irregular heartbeats, chest pain, and adrenal gland suppression with long-term use.

Precautions

Use with caution in patients with glaucoma, prostate problems, bladder blockage, heart rhythm disorders, and kidney disease. It is not recommended for children below 18 years of age. Avoid alcohol consumption during treatment as it may increase the risk of side effects. Inform your doctor if you have other medical conditions or are taking other medications.

Storage

Store TRIOHALE ROTACAPS below 25°C, protected from direct sunlight, and do not freeze. Keep out of reach of children and pets.

TRIOHALE ROTACAPS: Frequently Asked Questions

TRIOHALE ROTACAPS, manufactured by Cipla Ltd, is a combination medication primarily used for the management of chronic obstructive pulmonary disease (COPD) and asthma. It delivers its active ingredients directly to the lungs through a Rotahaler device.

What is TRIOHALE ROTACAPS used for?

TRIOHALE ROTACAPS is used for the long-term management of severe chronic obstructive pulmonary disease (COPD) and asthma. It helps alleviate symptoms such as wheezing, shortness of breath, chest tightness, and coughing, and reduces the frequency and severity of COPD exacerbations. It is not meant for immediate relief of sudden breathing problems; a rescue inhaler should be used for such emergencies.

How does TRIOHALE ROTACAPS work?

TRIOHALE ROTACAPS contains three active ingredients: Tiotropium, Formoterol, and Ciclesonide.

• Tiotropium (an anticholinergic) works by relaxing the muscles around the airways, helping to open them up and making it easier to breathe.
• Formoterol (a long-acting beta-agonist or LABA) also relaxes the muscles in the airways, contributing to bronchodilation and easier breathing.
• Ciclesonide (a corticosteroid) reduces inflammation, swelling, and irritation in the airways, which is a key factor in COPD and asthma. Together, these components work synergistically to improve respiratory function, reduce wheezing and breathlessness, and help clear mucus.

What is the usual dosage for TRIOHALE ROTACAPS?

The recommended dosage for TRIOHALE ROTACAPS is one Rotacap inhaled once daily, using a Cipla Rotahaler or Revolizer device. It should be used at the same time each day. It is important not to use it more than once a day.

What are the possible side effects of TRIOHALE ROTACAPS?

Common side effects can include dry mouth, dry throat, headache, cough, hoarseness of voice, sore throat, increased heart rate, and fungal infections in the mouth (oropharyngeal candidiasis). Other possible side effects include constipation, urinary difficulty or retention, blurred vision, nausea, vomiting, and tremors. Rinsing your mouth with water after each inhalation can help prevent fungal infections. If side effects persist or worsen, consult your doctor.

Is TRIOHALE ROTACAPS safe during pregnancy or breastfeeding?

TRIOHALE ROTACAPS is generally not recommended during pregnancy unless absolutely necessary and if the potential benefits outweigh the risks, as limited human data exists and animal studies have shown potential harmful effects. For breastfeeding mothers, it is unknown whether the active ingredients are excreted in human breast milk. It should only be used if the expected benefit to the mother is greater than any possible risk to the child, and a doctor should be consulted.

Can TRIOHALE ROTACAPS be taken with other medications?

Care should be taken when using TRIOHALE ROTACAPS with certain medications. It is advisable to avoid taking other anticholinergic medicines with Tiotropium. Formoterol may interact with diuretics, steroids, antidepressants, or beta-blockers, potentially increasing the risk of heart or potassium problems. Strong enzyme blockers, such as ketoconazole, can increase Ciclesonide levels and side effects. Always inform your doctor about all medications, supplements, and herbal products you are taking.

What precautions should be taken while using TRIOHALE ROTACAPS?

Do not swallow the capsules; they are for inhalation only using the Rotahaler device. It is crucial to have the correct inhaler technique for the medicine to be effective. Do not stop taking the medicine suddenly, even if symptoms improve, as this can worsen breathing problems. Individuals with conditions such as eye issues (e.g., glaucoma), prostate problems, kidney problems, heart conditions, or diabetes should use this medicine with caution and under medical supervision. Avoid consuming alcohol while on this medication as it may increase the risk of side effects.

What happens if a dose of TRIOHALE ROTACAPS is missed?

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.

How should TRIOHALE ROTACAPS be stored?

Store TRIOHALE ROTACAPS below 25°C, protected from direct sunlight. Do not store above 25°C or freeze. Keep the capsules away from children and pets. Do not wet the capsules.