Empazio M Xr 12.5/1000mg Tab

EMPAZIO M XR 12.5/1000MG Tablet

Name:

• Brand Name: EMPAZIO M XR 12.5/1000MG Tablet
• Manufacturer: Torrent Pharmaceuticals Ltd.

Composition: Each extended-release tablet contains:

• Empagliflozin: 12.5 mg
• Metformin: 1000 mg

Uses: EMPAZIO M XR is prescribed for the management of Type 2 Diabetes Mellitus in adults. It is used alongside diet and exercise to improve blood sugar control. This medicine helps by removing excess sugar from the body through urine (Empagliflozin) and by improving the body's sensitivity to insulin while lowering glucose production in the liver (Metformin). It also helps prevent serious complications of diabetes such as kidney damage, blindness, nerve damage, and can reduce the risk of cardiovascular events like heart attack and heart failure in patients with Type 2 diabetes who also have cardiovascular disease.

Dosage and Administration: EMPAZIO M XR should be taken orally as directed by a physician, usually once daily with food, preferably at the same time each day. The tablet should be swallowed whole and not cut, broken, or chewed. Do not discontinue the medicine abruptly without consulting a doctor, as this may lead to increased blood sugar levels and a higher risk of complications.

Side Effects: Common side effects may include:

• Frequent urination
• Mild skin rash or itchy skin
• Nausea, vomiting, diarrhea, stomach ache, and loss of appetite
• Urinary tract infection (UTI)
• Genital fungal infection
• Nasopharyngitis (inflammation of the throat and nasal passages)
• Joint pain

Serious side effects can include dehydration, hypoglycemia (low blood sugar) especially when used with other antidiabetic medicines or alcohol, and lactic acidosis (symptoms like trouble breathing, unusual muscle pain, weakness, irregular heartbeats).

Precautions:

• Not recommended for Type 1 Diabetes Mellitus or severe kidney or liver disease.
• Caution is advised during pregnancy and breastfeeding; consult a doctor to discuss risks and benefits.
• Alcohol consumption should be limited or avoided due to increased risk of lactic acidosis and low blood sugar.
• Dehydration should be prevented by drinking plenty of fluids, especially in cases of severe vomiting, diarrhea, or excessive sweating.
• Alertness may be decreased; avoid driving or operating machinery if you experience dizziness or vision changes.
• Inform your doctor about all medications, including diuretics, insulin, sulphonylureas, and other specific drug interactions mentioned in patient information.
• Regular monitoring of blood sugar levels is essential.

Storage: Store in a cool and dry place, away from direct sunlight, at room temperature (below 30°C). Keep the medicine in its original packaging, protected from light and moisture, and out of reach of children and pets.

Here are frequently asked questions about EMPAZIO M XR 12.5/1000MG Tablet:

What is EMPAZIO M XR 12.5/1000MG Tablet used for?

EMPAZIO M XR 12.5/1000MG Tablet is primarily used with diet and exercise to improve blood sugar control in adults with Type 2 Diabetes Mellitus. It is also indicated to reduce the risk of cardiovascular death in adults with Type 2 Diabetes and established cardiovascular disease, and to reduce the risk of cardiovascular death and hospitalization for heart failure in adults with heart failure. Additionally, it can help reduce the risk of worsening kidney disease, end-stage kidney disease, and hospitalization in patients with chronic kidney disease.

How does EMPAZIO M XR 12.5/1000MG Tablet work?

This medicine contains two active ingredients: Empagliflozin and Metformin. Empagliflozin, a sodium-glucose co-transporter-2 (SGLT2) inhibitor, works by blocking the reabsorption of glucose by the kidneys, leading to increased glucose excretion in the urine and thus lowering blood sugar levels. Metformin, a biguanide, reduces glucose production in the liver, enhances the body's sensitivity to insulin, and slows down the absorption of glucose from the intestines.

What is the usual dosage for EMPAZIO M XR 12.5/1000MG Tablet?

EMPAZIO M XR 12.5/1000MG is an extended-release tablet typically taken once daily with food, preferably in the morning. Your doctor will determine the appropriate dose and may adjust it based on your individual needs. It is crucial to swallow the tablet whole without crushing, breaking, or chewing it. The maximum daily dose is generally not more than 25 mg of empagliflozin and 2000 mg of metformin.

What are the possible side effects of EMPAZIO M XR 12.5/1000MG Tablet?

Common side effects may include urinary tract infections, genital yeast infections, frequent urination, nausea, vomiting, diarrhea, headache, gas, and abdominal discomfort. More serious but rare side effects include lactic acidosis (symptoms like unusual muscle pain, stomach discomfort, or trouble breathing), ketoacidosis, dehydration, low blood pressure, acute kidney injury, and a rare bacterial infection called Fournier's gangrene. There is also a potential for an increased risk of lower limb amputation.

Is EMPAZIO M XR 12.5/1000MG Tablet safe during pregnancy or breastfeeding?

Pregnancy: This medicine is not recommended during the second and third trimesters of pregnancy as it could potentially harm an unborn baby. If you are pregnant or planning to become pregnant, discuss this with your doctor. If you have irregular periods, this medicine may cause you to ovulate, so it's important to discuss birth control options. Breastfeeding: EMPAZIO M XR is generally not recommended while breastfeeding, as it is unknown how much of the medication passes into breast milk and could potentially affect the infant's blood sugar levels or kidney development. Consult your doctor for alternative options.

Can EMPAZIO M XR 12.5/1000MG Tablet be taken with other medications?

It is important to inform your doctor about all medications you are taking, including over-the-counter drugs, vitamins, and herbal supplements. Concomitant use with insulin or insulin secretagogues (e.g., sulfonylureas) may increase the risk of low blood sugar (hypoglycemia), potentially requiring a dose adjustment. Diuretics may increase the risk of volume depletion. Certain medications, such as carbonic anhydrase inhibitors or those affecting kidney function, can increase the risk of lactic acidosis. You may also need to temporarily stop this medication before procedures involving iodinated contrast dyes.

What precautions should be taken while using EMPAZIO M XR 12.5/1000MG Tablet?

Before starting this medication, inform your doctor if you have kidney disease, liver disease, heart failure, a history of pancreatitis, urinary tract or genital yeast infections, or leg/foot problems. Your kidney function should be assessed before and periodically during treatment. Any dehydration should be corrected prior to starting the medication. Do not use if you have severe kidney disease or an allergy to empagliflozin or metformin. You may need to temporarily stop taking this medicine several days before surgery or medical tests that require fasting. Maintain adequate hydration and monitor your blood sugar regularly.

What happens if a dose of EMPAZIO M XR 12.5/1000MG Tablet is missed?

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and resume your regular dosing schedule. Do not take a double dose to make up for a missed one. If you frequently miss doses, consider setting an alarm or using a reminder.

How should EMPAZIO M XR 12.5/1000MG Tablet be stored?

Store EMPAZIO M XR 12.5/1000MG Tablet at room temperature, typically between 68°F to 77°F (20°C to 25°C). Keep it in a closed container, away from excessive heat, moisture, and direct light, and out of the reach of children.