Sibelium 10 Mg Tablet (30 Tab)

Sibelium 10 mg Tablet, manufactured by Johnson & Johnson Pharma (Janssen Pharmaceuticals), is a medication primarily used for the prophylaxis of migraines.

Name

• Brand Name: SIBELIUM 10 MG TABLET
• Common Name: Flunarizine

Composition

• Active Ingredient: Each tablet contains Flunarizine hydrochloride equivalent to 10 mg Flunarizine.
• Class: Calcium Channel Blocker

Uses

Sibelium 10 mg Tablet is prescribed for:

• Migraine Prophylaxis: Prevention of classic (with aura) or common (without aura) migraine headaches by regulating calcium channels in the brain and preventing abnormal dilation of blood vessels. It helps reduce the frequency and intensity of migraine episodes but is not for treating acute attacks.
• Vestibular Disorders: Symptomatic treatment of vestibular vertigo due to a diagnosed functional disorder of the vestibular system.
• Cerebral Insufficiency: May be indicated for symptoms like memory disturbances and concentration difficulties.

Dosage and Administration

• Adults (18-64 years): The typical starting dose for migraine prophylaxis is 10 mg once daily, usually taken at night.
• Elderly (65 years and older): A starting dose of 5 mg daily is recommended.
• The tablet should be swallowed whole with water, preferably at the same time each day to maintain consistent levels in the body.
• Do not crush or chew the tablet.
• It is crucial to follow the doctor's prescribed duration and not to discontinue the medication suddenly. If no significant improvement is seen after 2 months for migraine or 1-2 months for vertigo, treatment should be re-evaluated.

Side Effects

Common side effects include:

• Drowsiness, fatigue, sleepiness, insomnia
• Weight gain, increased appetite
• Muscle pain, stomach discomfort, constipation, nausea
• Runny nose
• Depression, changes in mood
• Breast pain, irregular menstruation

If serious side effects or worsening of any symptoms occur, consult a doctor immediately.

Precautions

• Contraindications: Sibelium 10 mg Tablet should not be used in individuals with an allergy to flunarizine, depressive illness, a history of recurrent depression, Parkinson's disease, or severe liver disorders. It is generally not recommended for children under 18 years.
• Alcohol: Avoid or limit alcohol consumption as it may amplify drowsiness.
• Driving/Operating Machinery: Exercise caution as the medicine may cause drowsiness, dizziness, or confusion, especially at the start of treatment.
• Pregnancy and Breastfeeding: Caution is advised. Consult a doctor before use if pregnant or breastfeeding.
• Drug Interactions: May enhance drowsiness caused by other central nervous system depressants (e.g., diazepam, alprazolam).
• Monitoring: Regular monitoring for mood changes or signs of depression is important.

Storage

Store Sibelium 10 mg Tablet at room temperature, ideally around 25°C or below 30°C. Protect the medicine from intense light, heat, and moisture. Keep out of sight and reach of children.

Sibelium 10 mg Tablet, containing Flunarizine, is a medication primarily used for the prevention of migraine headaches. It's also used to manage dizziness and vertigo associated with vestibular disorders.

Here are some frequently asked questions about Sibelium 10 mg Tablet:

What is Sibelium 10 mg Tablet used for?

Sibelium 10 mg Tablet is primarily used to prevent migraine attacks, especially in individuals who experience frequent and severe episodes. It is also prescribed for the symptomatic treatment of vestibular vertigo (dizziness and balance problems) and in cases of cerebral insufficiency. It does not treat acute migraine attacks.

How does Sibelium 10 mg Tablet work?

Sibelium 10 mg Tablet contains flunarizine, which is a selective calcium antagonist (or calcium channel blocker). It works by preventing the abnormal dilation of blood vessels in the brain and regulating blood flow, which helps reduce the occurrence and intensity of migraines. It may also decrease the overexcitability of brain neurons by blocking calcium entry.

What is the usual dosage for Sibelium 10 mg Tablet?

For adults aged 18 to 64 years, the starting dose for migraine prophylaxis is typically 10 mg daily, taken at night. For elderly patients (65 years and older), the starting dose is 5 mg daily. Your doctor will determine the appropriate dosage and duration based on your medical condition and response to the treatment. It should be taken at the same time each day, preferably at night, to maintain consistent levels in the body.

What are the possible side effects of Sibelium 10 mg Tablet?

Common side effects can include drowsiness, fatigue, weight gain, increased appetite, muscle pain, constipation, nausea, insomnia (difficulty sleeping), and a runny or blocked nose. Some individuals may also experience depression, stomach discomfort, or breast pain. Most of these side effects are temporary and resolve over time, but if they persist or worsen, you should consult your doctor.

Is Sibelium 10 mg Tablet safe during pregnancy or breastfeeding?

Sibelium 10 mg Tablet is generally not recommended during pregnancy or breastfeeding. Limited information is available regarding its effects in human pregnancy, and it is unknown if flunarizine passes into breast milk. It is important to consult your doctor if you are pregnant, planning a pregnancy, or breastfeeding before taking this medicine.

Can Sibelium 10 mg Tablet be taken with other medications?

Sibelium 10 mg Tablet can interact with other medications, especially those that affect the central nervous system. These include sleeping pills, anti-anxiety medicines (like diazepam or alprazolam), muscle relaxants, tranquilizers, and anti-seizure medications (such as phenytoin or carbamazepine), as co-administration may increase drowsiness or alter effectiveness. It's crucial to inform your doctor about all medications, including over-the-counter drugs and herbal preparations, that you are taking.

What precautions should be taken?

You should inform your doctor before taking Sibelium 10 mg Tablet if you have a history of depression, Parkinson's disease, or liver or kidney disorders. This medicine can cause drowsiness, so avoid driving or operating machinery until you understand how it affects you. Alcohol consumption should be limited or avoided as it can increase drowsiness. Regular monitoring by your doctor is recommended during long-term treatment.

What happens if a dose is missed?

If you miss a dose, take it as soon as you remember. However, if it's almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for the forgotten one.

How should Sibelium 10 mg Tablet be stored?

Sibelium 10 mg Tablet should be stored in a cool and dry place, below 30°C, away from direct sunlight, moisture, and heat. Keep it out of the sight and reach of children and pets. Ensure it is used before the expiration date printed on the pack.