Rekool L Tablet

REKOOL L TABLET by ALEMBIC PHARMACEUTICALS LTD

REKOOL L TABLET is a prescription medicine manufactured by Alembic Pharmaceuticals Ltd. It is commonly used to treat various gastrointestinal conditions.

Composition

REKOOL L TABLET is a fixed-dose combination containing two active ingredients:

• Rabeprazole (20 mg): A proton pump inhibitor (PPI) that reduces the production of stomach acid.
• Levosulpiride (75 mg): A prokinetic agent and selective dopamine D2 receptor antagonist that enhances gastrointestinal motility and helps prevent the backflow of acid into the food pipe.

Uses

REKOOL L TABLET is primarily prescribed for the treatment of:

• Gastroesophageal Reflux Disease (GERD), including acid reflux and heartburn
• Intestinal Ulcers (duodenal and gastric ulcers)
• Irritable Bowel Syndrome (IBS)
• Zollinger-Ellison Syndrome
• Acidity, indigestion, and chronic gastritis
• Helicobacter pylori infection (in combination therapy)

Dosage and Administration

The dosage and duration should be strictly as advised by a healthcare professional.

• Typically, one tablet is taken daily.
• It is often recommended to take it on an empty stomach, preferably in the morning, one hour before a meal.
• Swallow the tablet whole with a glass of water; do not chew, crush, or break it.
• Do not stop treatment prematurely, even if symptoms improve, as this may lead to their return.

Side Effects

While generally well-tolerated, some common side effects may include:

• Nausea, vomiting, stomach pain, diarrhea, constipation, and flatulence
• Headache, dizziness, sleepiness, and weakness
• Flu-like symptoms, cough, and back pain

More serious or less common side effects can include:

• Breast enlargement in males (gynecomastia) or unusual breast milk production in men and women (galactorrhea)
• Absence of menstrual periods
• Abnormal body movements (e.g., twitching, tremors, tardive dyskinesia)
• Long-term use may be associated with an increased risk of osteoporosis-related fractures and hypomagnesemia.

Precautions

• Allergies: Do not take if allergic to rabeprazole, levosulpiride, or any other components.
• Alcohol: Avoid alcohol consumption as it can increase the risk of stomach damage and other side effects like confusion and drowsiness.
• Pregnancy & Breastfeeding: Consult a doctor. Rekool-L Tablet may be unsafe during pregnancy and is generally not recommended for breastfeeding women.
• Driving & Operating Machinery: This medicine may cause dizziness or sleepiness; avoid such activities if affected.
• Pre-existing Conditions: Use with caution in patients with severe liver disease, kidney disease, epilepsy, pheochromocytoma, bipolar disorder, cardiovascular diseases, diabetes, lupus, or a history of osteoporosis. Inform your doctor about any gastrointestinal bleeding, obstruction, or perforation.
• Children: Not recommended for use in children as safety and effectiveness have not been established.
• Drug Interactions: Inform your doctor about all other medications, including over-the-counter drugs and supplements, as potential drug-drug interactions may occur.

Storage

Store REKOOL L TABLET at room temperature (20-25°C), away from heat, direct sunlight, and moisture. Keep it out of reach and sight of children and pets.

Here are frequently asked questions about REKOOL L TABLET:

What is REKOOL L TABLET used for?

REKOOL L TABLET is a prescription medicine primarily used to treat gastroesophageal reflux disease (GERD), also known as acid reflux, which is a long-term condition involving excessive stomach acid production. It is also used for intestinal ulcers, irritable bowel syndrome (IBS), peptic ulcers, Zollinger-Ellison syndrome, functional dyspepsia, diabetic gastroparesis, chronic gastritis, and to alleviate symptoms like heartburn, acidity, indigestion, dizziness, and nausea.

How does REKOOL L TABLET work?

REKOOL L TABLET is a combination of two medicines: Rabeprazole and Levosulpiride. Rabeprazole is a proton pump inhibitor (PPI) that works by reducing the amount of acid produced in the stomach. Levosulpiride is a prokinetic agent and selective dopamine D2 receptor antagonist that increases the movement of the stomach and intestines, helping to prevent acid and food from flowing back into the food pipe. This dual action helps relieve acid-related symptoms and promotes healing.

What is the usual dosage for REKOOL L TABLET?

The dosage of REKOOL L TABLET should be taken as advised by your doctor, as it depends on your specific condition and response to the medicine. Generally, it is recommended to take one tablet daily on an empty stomach, preferably one hour before a meal, usually in the morning. Swallow the tablet whole; do not chew, crush, or break it.

What are the possible side effects of REKOOL L TABLET?

Common side effects can include nausea, stomach pain, diarrhea, flatulence, constipation, headache, dizziness, weakness, sleepiness, and flu-like symptoms. Some individuals might also experience cough, breast enlargement in males, altered libido, absence of menstrual periods, or unusual breast milk production in women and men. If you experience severe or persistent side effects, or unusual symptoms like severe watery diarrhea, fever, or skin rash, consult your doctor immediately.

Is REKOOL L TABLET safe during pregnancy or breastfeeding?

REKOOL L TABLET is generally not recommended for use during pregnancy unless specifically prescribed by a doctor who has carefully weighed the potential benefits against the risks. It is strictly not recommended for breastfeeding women, as information regarding its use during breastfeeding is limited or it may pass into breast milk. Always consult your doctor if you are pregnant, planning pregnancy, or breastfeeding.

Can REKOOL L TABLET be taken with other medications?

It's crucial to inform your doctor about all other medications you are taking, including over-the-counter drugs, herbal supplements, and dietary supplements, as REKOOL L TABLET can interact with certain medicines. Notable interactions include blood thinners (e.g., warfarin), antifungals (e.g., ketoconazole), some HIV medications (e.g., atazanavir, nelfinavir), anticholinergics, and Levodopa. Antacids should not be taken simultaneously with REKOOL L TABLET.

What precautions should be taken while taking REKOOL L TABLET?

Avoid consuming alcohol while taking REKOOL L TABLET as it can increase the risk of side effects like drowsiness and stomach damage. If you experience dizziness or sleepiness, do not drive or operate heavy machinery. Inform your doctor if you have kidney or liver disease, heart conditions, a history of epilepsy, pheochromocytoma, breast cancer, gastrointestinal bleeding, intestinal obstruction, or low vitamin B12 levels. Long-term use (over one year) may increase the risk of bone fractures, so ensure adequate calcium and Vitamin D intake. This medicine is not recommended for children under 18 years of age.

What happens if a dose of REKOOL L TABLET is missed?

If you miss a dose of REKOOL L TABLET, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed one.

How should REKOOL L TABLET be stored?

REKOOL L TABLET should be stored at room temperature, typically between 20-25°C. Keep it in its original packaging, tightly closed, away from heat, direct light, and moisture. Ensure it is kept out of reach of children and pets.