Prostagard D 4 Mg Capsule (10 Cap)

PROSTAGARD D 4 MG CAPSULE

PROSTAGARD D 4 MG CAPSULE is a medication manufactured by Aristo Pharmaceuticals Private Limited.

• Name: Prostagard D 4 Capsule, Prostagard D 4/0.5mg Capsule.
• Composition: Each hard gelatin capsule contains Silodosin 4 mg (as granules) and Dutasteride IP 0.5 mg (as uncoated tablet).
  • Silodosin: An alpha-adrenergic antagonist that relaxes smooth muscles in the prostate gland, urethra, and urinary bladder, easing urinary flow.
  • Dutasteride: A 5-alpha reductase inhibitor that reduces the production of dihydrotestosterone (DHT), a hormone responsible for the initial development and enlargement of the prostate gland.
• Uses: PROSTAGARD D 4 MG CAPSULE is used for the management of Benign Prostatic Hyperplasia (BPH) or enlarged prostate in men. It provides symptomatic relief from lower urinary tract symptoms such as difficulty in urination, dribbling of urine, weak stream of urine, frequent urination (especially at night), and incomplete emptying of the bladder.
• Dosage and Administration: This medicine should be taken orally, preferably with meals, and at a fixed daily time. The capsule should be swallowed whole and not crushed or chewed. The dosage and duration of treatment are determined by a doctor.
• Side Effects: Common side effects include:
  • Dizziness
  • Orthostatic Hypotension/Postural Hypotension (low blood pressure upon standing)
  • Headache
  • Diarrhea
  • Stuffy or runny nose (Nasopharyngitis)
  • Decreased libido
  • Ejaculation disorder
  • Breast enlargement (gynecomastia) and tenderness in males
  • Nausea or vomiting
• Precautions:
  • Allergy: Avoid if allergic to silodosin, dutasteride, or any other ingredients.
  • Liver/Kidney Impairment: Not recommended for patients with severe liver or kidney disease. Use with caution in mild to moderate cases, with dose adjustment under medical supervision.
  • Alcohol: Avoid alcohol consumption as it can aggravate orthostatic hypotension, dizziness, and drowsiness.
  • Driving & Operating Machines: May cause postural hypotension and dizziness, impairing the ability to drive or operate machinery.
  • Pregnancy/Breastfeeding: Not applicable, as this medicine is for men and not indicated for use in women or children.
  • Drug Interactions: Caution is advised with antifungals (e.g., ketoconazole, itraconazole), antivirals (e.g., ritonavir), immunosuppressants (e.g., cyclosporine), and blood pressure-lowering medicines (e.g., verapamil, diltiazem), as these can increase side effects or alter effectiveness. Erectile dysfunction medicines (PDE-5 inhibitors like tadalafil and sildenafil) can increase the risk of orthostatic hypotension.
  • Blood Donation: Do not donate blood until 6 months after the last dose to prevent transfusion to pregnant women.
  • Cataract Surgery: Inform your eye doctor about the use of this medicine if you are scheduled for cataract or glaucoma surgery.
• Storage: Store in a cool and dry place, away from sunlight and moisture, at a temperature not exceeding 30°C. Keep out of sight and reach of children.

PROSTAGARD D 4 MG CAPSULE is a medication primarily used to manage the symptoms of benign prostatic hyperplasia (BPH), also known as an enlarged prostate, in men. It is a combination medicine containing Silodosin (4 mg) and Dutasteride (0.5 mg).

Here are some frequently asked questions about PROSTAGARD D 4 MG CAPSULE:

What is PROSTAGARD D 4 MG CAPSULE used for?

PROSTAGARD D 4 MG CAPSULE is used to treat the signs and symptoms of Benign Prostatic Hyperplasia (BPH) or an enlarged prostate gland in adult men. This condition can lead to lower urinary tract symptoms such as difficulty in urination, a weak urine stream, frequent urination (especially at night), urgency to urinate, and incomplete emptying of the bladder. The medicine helps relieve these symptoms and improves the quality of life, though it does not cure BPH. It is not used to prevent prostate cancer.

How does PROSTAGARD D 4 MG CAPSULE work?

PROSTAGARD D 4 MG CAPSULE is a combination of two active ingredients: Silodosin and Dutasteride. Silodosin is an alpha-blocker that works by relaxing the smooth muscles in the prostate gland, bladder, and urethra, which helps to improve urine flow. Dutasteride is a 5-alpha reductase inhibitor that reduces the production of dihydrotestosterone (DHT), a hormone responsible for prostate growth. By lowering DHT levels, Dutasteride helps to shrink the enlarged prostate gland over time.

What is the usual dosage for PROSTAGARD D 4 MG CAPSULE?

The typical dosage is one capsule once daily. It should be swallowed whole with a glass of water, preferably after a meal, and not crushed, chewed, or opened. It is recommended to take the medicine at the same time each day to maintain consistent levels in your body. Always follow your doctor's instructions regarding the exact dosage and duration of treatment.

What are the possible side effects of PROSTAGARD D 4 MG CAPSULE?

Common side effects can include dizziness, orthostatic hypotension (a sudden drop in blood pressure upon standing up), headache, stuffy or runny nose (nasopharyngitis), diarrhea, decreased libido (sex drive), abnormal ejaculation, and impotence. Breast enlargement and tenderness in males have also been reported. Most side effects are usually temporary and resolve as your body adjusts to the medicine. If any side effects persist or worsen, consult your doctor.

Is PROSTAGARD D 4 MG CAPSULE safe during pregnancy or breastfeeding?

PROSTAGARD D 4 MG CAPSULE is strictly for use in men and is not indicated for women or children. It is contraindicated during pregnancy, especially due to the Dutasteride component, which can cause severe harm to a male fetus. It is also not known if the medicine passes into breast milk, making it contraindicated for breastfeeding women. Men taking this medication should not donate blood for at least 6 months after their last dose to prevent potential exposure to pregnant women through blood transfusion.

Can PROSTAGARD D 4 MG CAPSULE be taken with other medications?

PROSTAGARD D 4 MG CAPSULE can interact with several medications. It should be used with caution or avoided with:

• Antifungal medicines (e.g., ketoconazole, itraconazole), antiviral medicines (e.g., ritonavir, lopinavir), and immunosuppressants (e.g., cyclosporine) as they can increase the effects and potential side effects of Prostagard D.
• Blood pressure-lowering medicines (e.g., prazosin, terazosin, verapamil, diltiazem, or other antihypertensive drugs) due to a significant risk of a severe drop in blood pressure.
• Erectile dysfunction medicines (e.g., sildenafil, tadalafil) as they can increase side effects like dizziness and orthostatic hypotension.
• Some antibiotics (e.g., clarithromycin, erythromycin) might reduce the effectiveness of this medicine. Always inform your doctor about all prescription and non-prescription medicines, supplements, or herbal products you are currently taking to avoid potential drug interactions.

What precautions should be taken while taking PROSTAGARD D 4 MG CAPSULE?

• Alcohol: Avoid alcohol consumption as it can increase dizziness and significantly lower blood pressure.
• Liver/Kidney Conditions: Inform your doctor if you have liver or kidney disorders. The medicine is not recommended for severe impairment and may require dose adjustment with mild to moderate conditions.
• Driving/Operating Machinery: Due to possible dizziness, low blood pressure, or blurred vision, it is advised to avoid driving or operating heavy machinery until you know how the medicine affects you.
• Allergies: Do not take this medicine if you are allergic to Silodosin, Dutasteride, or any other ingredients.
• Eye Surgery: Inform your eye doctor about taking this medication if you are scheduled for cataract or glaucoma surgery.
• Low Blood Pressure: Use with caution if you have a history of low blood pressure.
• Prostate Cancer: Your doctor may conduct tests to rule out prostate cancer before starting treatment, as BPH symptoms can be similar.
• Elderly Patients: Older patients may be more sensitive to side effects, particularly dizziness and low blood pressure when changing positions.

What happens if a dose of PROSTAGARD D 4 MG CAPSULE is missed?

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.

How should PROSTAGARD D 4 MG CAPSULE be stored?

Store PROSTAGARD D 4 MG CAPSULE below 30°C in a cool and dry place. Keep it protected from light and moisture, and out of the reach of children and pets.