Sitalong Dm-10/100/1000 (10 Tab)

SITALONG DM-10/100/1000

SITALONG DM-10/100/1000 is a prescription medication manufactured by Alteus Biogenics Pvt. Ltd., used for the management of Type 2 Diabetes Mellitus. It is available in tablet form, typically in strips of 10 tablets.

• Composition Each tablet contains a combination of three active ingredients:

  • Dapagliflozin: 10 mg
  • Sitagliptin: 100 mg
  • Metformin: 1000 mg

• Uses SITALONG DM-10/100/1000 is prescribed for adults with Type 2 Diabetes Mellitus to improve blood sugar control. It is used as an adjunct to diet and exercise, especially when conventional therapies or dual combination therapy do not achieve adequate glycemic control. This medication also offers benefits in cardiovascular and kidney protection, weight and metabolic control, and reduction of HbA1c levels. It is not recommended for Type 1 diabetes or diabetic ketoacidosis.

• Dosage and Administration This medication should be taken exactly as advised by a healthcare professional. The tablet should be swallowed whole with water and not chewed, crushed, or broken. It can generally be taken with or without food, though some sources suggest taking it with food, particularly due to its Metformin component. It is crucial to take it at the same time every day for consistent effect and not to stop the medication without consulting a doctor.

• Side Effects Common side effects may include female genital mycotic infections, urinary tract infections, nasopharyngitis, diarrhea, headache, nausea, vomiting, abdominal pain, upset stomach, nasal congestion, and sore throat. Rarely, a serious condition called lactic acidosis can occur. Patients should be aware of symptoms of low blood sugar (hypoglycemia) such as anger, shaking, or a fast heartbeat.

• Precautions SITALONG DM-10/100/1000 is contraindicated in individuals with severe renal impairment, end-stage renal disease, or those undergoing dialysis. Caution is advised for patients with hepatic impairment, cardiac insufficiency, coronary artery disease, hypertension, or gastrointestinal disorders. Pregnant or breastfeeding women should consult their doctor before use, as it is generally not recommended. Excessive alcohol consumption should be avoided as it can intensify side effects and affect blood glucose levels. Inform your doctor about all other medications, including diuretics, beta-blockers, or birth control pills, to avoid potential drug interactions. Regular monitoring of blood sugar levels and kidney function is important.

• Storage The tablets should be kept in a tightly sealed container and stored at room temperature, ideally below 30°C (or between 10°C to 25°C). Protect the medicine from moisture and humidity, and ensure it is kept out of the reach of children.

Here are some frequently asked questions about SITALONG DM-10/100/1000:

What is SITALONG DM-10/100/1000 used for?

SITALONG DM-10/100/1000 is primarily used to manage blood sugar levels in adults with type 2 diabetes mellitus. It is prescribed when diet, exercise, and therapy with conventional medicines do not provide an adequate response. This medication also aids in improving glycemic control beyond what dual combination therapy can offer, helps reduce the risk of cardiovascular events, supports weight loss, and offers kidney protection. It is not intended for type 1 diabetes or diabetic ketoacidosis.

How does SITALONG DM-10/100/1000 work?

SITALONG DM-10/100/1000 contains three active ingredients: Dapagliflozin, Sitagliptin, and Metformin.

• Dapagliflozin (10 mg), an SGLT2 inhibitor, reduces blood glucose by decreasing glucose reabsorption in the kidneys and increasing its excretion through urine, independent of insulin levels.
• Sitagliptin (100 mg), a DPP-4 inhibitor, increases the levels of natural substances (incretins) that lower blood sugar when it is high by enhancing insulin release and decreasing glucagon levels.
• Metformin (1000 mg), a biguanide, lowers blood sugar by reducing glucose production in the liver, delaying sugar absorption from the intestines, and improving the body's sensitivity to insulin.

What is the usual dosage for SITALONG DM-10/100/1000?

The daily dosage of SITALONG DM-10/100/1000 is determined by your doctor based on your health condition and how you respond to the medicine. It is crucial not to change the prescribed dose without consulting your doctor. The tablet should be swallowed whole with water and not chewed or crushed. It can be taken with or without food, but taking it at the same time each day is recommended, and taking it with food may help minimize gastrointestinal side effects.

What are the possible side effects of SITALONG DM-10/100/1000?

Common side effects of SITALONG DM-10/100/1000 include female genital mycotic infections, nasopharyngitis (inflammation of the throat and nasal passages), urinary tract infections, diarrhea, headache, nausea, and vomiting. Most of these side effects are temporary and resolve over time. If they persist or worsen, you should consult your doctor. Lactic acidosis is a rare but serious side effect that can occur due to metformin accumulation.

Is SITALONG DM-10/100/1000 safe during pregnancy or breastfeeding?

If you are pregnant, planning to conceive, or breastfeeding, it is best to consult your doctor before taking SITALONG DM-10/100/1000. Information regarding its use during pregnancy and breastfeeding is not readily available, and it is generally not recommended in these situations, as some ingredients may harm the baby or affect milk production.

Can SITALONG DM-10/100/1000 be taken with other medications?

SITALONG DM-10/100/1000 can interact with certain medications.

• Thiazide Diuretics (e.g., hydrochlorothiazide) may increase the risk of dehydration and low blood pressure.
• Loop Diuretics (e.g., furosemide) may increase the risk of lactic acidosis.
• Carbonic Anhydrase Inhibitors (e.g., acetazolamide) may also increase the risk of lactic acidosis.
• Insulin or insulin secretagogues (e.g., glipizide) may increase the risk of hypoglycemia, potentially requiring a lower dose of these medicines. It is important to inform your doctor about all other medicines, herbal supplements, and vitamins you are taking to avoid potential interactions.

What precautions should be taken with SITALONG DM-10/100/1000?

Several precautions should be taken:

• Kidney and Liver Impairment: It is not recommended for individuals with severe renal impairment or those undergoing dialysis, and caution is advised for people with liver diseases due to potential risks associated with metformin.
• Alcohol Consumption: Caution is advised with alcohol intake as it can intensify some side effects, affect blood glucose levels, and increase the risk of hypoglycemia and lactic acidosis.
• Dehydration: Drinking plenty of fluids is important to prevent dehydration, as one of the components increases glucose excretion through urine.
• Hypoglycemia: Low blood sugar can occur, especially if taken with other antidiabetic medicines, alcohol, or if meals are delayed or skipped.
• Allergies: Do not take this medicine if you are allergic to any of its components.
• Children: It is not recommended for use in children below 18 years of age.

What happens if a dose of SITALONG DM-10/100/1000 is missed?

If you miss a dose of SITALONG DM-10/100/1000, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed one and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one, as this is not recommended and may cause your blood sugar level to fall rapidly.

How should SITALONG DM-10/100/1000 be stored?

SITALONG DM-10/100/1000 should be kept in a tightly sealed container and stored at room temperature, ideally below 30°C. Protect the medicine from moisture and humidity to maintain its effectiveness. Always ensure that this medicine is out of the sight and reach of children.