Niftran 100 Cp 30c

NIFTRAN 100 CP Capsules

NIFTRAN 100 CP is an antibiotic medication primarily prescribed for the treatment and prevention of bacterial urinary tract infections (UTIs).

• Name

  • Brand Name: NIFTRAN 100 CP
  • Common Name/Active Ingredient: Nitrofurantoin

• Composition

  • Each capsule contains Nitrofurantoin 100 mg.

• Uses NIFTRAN 100 CP is used to manage and prevent various bacterial infections of the urinary tract, including:

  • Uncomplicated urinary tract infections (UTIs)
  • Bladder infections (cystitis)
  • Kidney infections
  • Infections caused by susceptible strains of bacteria such as Escherichia coli, Staphylococcus aureus, Klebsiella species, and Enterobacter species.

• Dosage and Administration

  • Typical Adult Dosage: For treating UTIs, the recommended adult dosage is usually 50 to 100 mg taken orally four times a day.
  • For Long-Term Prevention: A dose of 50 to 100 mg once daily at bedtime may be prescribed.
  • Administration: Capsules should be swallowed whole with food or milk to enhance absorption and minimize stomach upset. Do not crush or chew the capsules.
  • It is crucial to complete the full course of medication as prescribed by your doctor, even if symptoms improve.

• Side Effects

  • Common Side Effects: Nausea, vomiting, loss of appetite, diarrhea, headache, flatulence, and dark yellow or brown urine.
  • Serious Side Effects (Rare): Seek immediate medical attention if you experience sudden wheezing, difficulty breathing, swelling of eyelids, face or lips, rash or itching affecting the whole body, fever, chills, cough, shortness of breath (indicating a lung reaction), yellowing of the skin or whites of the eyes (jaundice/liver inflammation), or peripheral neuropathy (tingling/weakness in hands and feet).

• Precautions

  • Contraindications: Not recommended for patients with known allergy to nitrofurantoin, severe kidney impairment (CrCl < 60 mL/min), anuria, acute porphyria, infants under 3 months of age, or pregnant women at term (38-42 weeks gestation), during labor and delivery.
  • Use with Caution: Advise caution in breastfeeding women (especially if the infant has G6PD deficiency), elderly patients, and individuals with lung or liver disease, anaemia, diabetes, severe weakness, electrolyte imbalance, or vitamin B deficiency.
  • Drug Interactions: Avoid concomitant use with magnesium-containing antacids (may interfere with absorption) and certain antigout medications like probenecid or sulfinpyrazone. It may also interact with medicines that slow stomach emptying (e.g., atropine) and those that make urine less acidic.
  • Other Warnings: NIFTRAN 100 CP may cause dizziness or drowsiness; avoid driving or operating machinery if affected. It may interfere with urine tests for sugar, leading to false positive results. Avoid alcohol consumption. Avoid grapefruit and excessive sun exposure.

• Storage Store NIFTRAN 100 CP capsules in a cool and dry place, protected from excessive heat, sunlight, and moisture. Keep out of reach of children.

Here are frequently asked questions about Niftran 100 CP:

What is Niftran 100 CP used for?

Niftran 100 CP, which contains nitrofurantoin, is primarily used to treat and prevent bacterial infections of the urinary tract (UTIs). This includes bladder infections (cystitis) and kidney infections. It works by stopping the growth of bacteria and clearing the infection.

How does Niftran 100 CP work?

Niftran 100 CP works by utilizing its active ingredient, nitrofurantoin. Nitrofurantoin enters bacterial cells and is converted into active forms that destroy the bacteria's genetic material and disrupt vital biochemical processes, leading to bacterial cell death.

What is the usual dosage for Niftran 100 CP?

The usual dosage for adults to treat an infection is typically 50 to 100 mg, taken four times a day for 7 days. For long-term prevention of recurrent UTIs, a dose of 50 to 100 mg once daily at bedtime may be prescribed. It is crucial to take the capsule whole with food or milk to reduce stomach upset and enhance effectiveness, as advised by your doctor. Do not crush, break, or chew the capsule.

What are the possible side effects of Niftran 100 CP?

Common side effects may include nausea, vomiting, diarrhea, loss of appetite, headaches, stomach pain, gas (flatulence), and drowsiness or dizziness. More serious, though rare, side effects can involve allergic reactions (e.g., wheezing, difficulty breathing, swelling of the face or lips), lung reactions (e.g., fever, chills, cough, shortness of breath), or liver inflammation (jaundice). If severe side effects occur, seek immediate medical attention. Your urine may also turn dark yellow or brown, which is a normal and harmless effect of the medicine.

Is Niftran 100 CP safe during pregnancy or breastfeeding?

Niftran 100 CP is generally not recommended for use during labor or delivery due to the possibility of affecting the baby. If you are pregnant, planning a pregnancy, or breastfeeding, it is essential to consult your doctor before taking this medicine. It should be used with caution in breastfeeding women and avoided if the infant has a known or suspected erythrocyte enzyme deficiency (including G6PD deficiency), as it may pass into breast milk.

Can Niftran 100 CP be taken with other medications?

Niftran 100 CP can interact with certain medications. Inform your doctor about all medicines, supplements, and herbal products you are currently taking. Particular interactions may occur with antacids containing magnesium trisilicate, medicines for gout (like probenecid or sulfinpyrazone), medicines that slow food passage through the stomach (e.g., atropine, hyoscine), carbonic anhydrase inhibitors (e.g., acetazolamide), medicines that make urine less acidic (e.g., potassium citrate mixture), some quinolone antibiotics, oral contraceptives, and the typhoid vaccine.

What precautions should be taken while taking Niftran 100 CP?

Do not take Niftran 100 CP if you are allergic to nitrofurantoin or any of its components. It is contraindicated in patients with severe kidney problems (including anuria, severe renal impairment, or eGFR less than 45 mL/minute), acute porphyria (a blood disorder), or glucose-6-phosphate dehydrogenase (G6PD) deficiency. Use with caution if you have lung or liver disease, diabetes, severe weakness, anemia, or vitamin B deficiency. As Niftran 100 CP may cause dizziness and drowsiness, it is advisable to avoid driving or operating machinery if you experience these effects. Alcohol consumption should be avoided while on this medication.

What happens if a dose of Niftran 100 CP is missed?

If you miss a dose of Niftran 100 CP, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a forgotten one.

How should Niftran 100 CP be stored?

Niftran 100 CP should be stored in a cool and dry place, protected from sunlight and moisture. Keep it out of sight and reach of children. It is generally recommended to store it at temperatures between 10ºC to 25ºC or below 30ºC.