Olvan Trio 20 Mg Tablet (10 Tab)

Olvan Trio 20 Tablet

Olvan Trio 20 Tablet is a medication manufactured by Sun Pharmaceutical Industries Ltd., primarily used for the management of hypertension, commonly known as high blood pressure. It is a combination medicine prescribed when a single medication is not sufficient to control blood pressure levels. This medication helps in reducing the risk of serious cardiovascular complications such as heart attack, stroke, and kidney problems.

Composition

Each Olvan Trio 20 Tablet contains a combination of three active ingredients:

• Olmesartan Medoxomil: 20mg (an Angiotensin Receptor Blocker (ARB))
• Cilnidipine: 10mg (a Calcium Channel Blocker (CCB))
• Chlorthalidone: 12.5mg (a diuretic or 'water pill')

These components work synergistically: Olmesartan relaxes blood vessels by blocking angiotensin, Cilnidipine further relaxes blood vessels and improves blood flow, and Chlorthalidone helps the body expel excess water and salt, thereby lowering blood pressure.

Uses

Olvan Trio 20 Tablet is prescribed for:

• Treatment of essential hypertension (high blood pressure) in adults.
• Reducing the risk of cardiovascular events and complications associated with uncontrolled high blood pressure.

Dosage and Administration

Take Olvan Trio 20 Tablet exactly as advised by your doctor. It is recommended to take the tablet with food, swallowing it whole without chewing, crushing, or breaking it. Consistency is key; try to take it at the same time each day. Do not stop taking the medication abruptly, even if you feel well, as high blood pressure often shows no symptoms and stopping can increase heart-related risks. Since it contains a diuretic, it's best to avoid taking it within four hours of bedtime to prevent sleep disturbance due to increased urination. The dosage will vary based on your condition and response to the medication.

Side Effects

Common Side Effects:

• Dizziness
• Headache
• Low blood pressure (hypotension)
• Flushing (reddening of the skin, especially face, ears, neck, and trunk)
• Palpitations (pounding heartbeat)
• Increased urination frequency
• Weakness or tiredness
• Ankle swelling
• Sleepiness
• Nausea, upset stomach, diarrhea, constipation
• Altered blood lipid levels, increased blood uric acid, glucose intolerance, taste change
• Muscle cramps, skin rash, pruritus (itching)

Serious Side Effects (seek immediate medical attention if experienced):

• Severe dizziness or fainting
• Muscle cramps or irregular heartbeat (may indicate low potassium)
• Yellowing of eyes or skin (signs of liver problems)
• Sudden weight gain or swelling (signs of kidney issues)
• Skin rash, itching, or trouble breathing (possible allergic reaction)

Precautions

• Allergies: Do not take if allergic to any of its components or sulfa drugs.
• Medical Conditions: Not recommended for individuals with severe kidney or liver disease, anuria (failure to produce urine), low blood pressure (hypotension), cardiogenic shock, aortic stenosis, low potassium/sodium levels, or high calcium/uric acid (gout).
• Pregnancy & Breastfeeding: Contraindicated during the second and third trimesters of pregnancy and generally not recommended for breastfeeding mothers. Consult your doctor if pregnant, planning pregnancy, or breastfeeding.
• Interactions: Avoid alcohol consumption as it may increase dizziness. Do not consume grapefruit juice or St. John's wort plant while on this medication. Inform your doctor about all other medications, especially those for high blood pressure, heart conditions, diabetes, gout, or anti-inflammatory drugs like ibuprofen, and avoid potassium-rich foods or supplements without medical advice.
• Monitoring: Regular monitoring of blood pressure, kidney function, electrolyte levels (potassium, sodium, magnesium), and blood sugar is crucial during treatment.
• Driving/Operating Machinery: May cause dizziness, so exercise caution when driving or operating heavy machinery.
• Children: Not recommended for use in children.

Storage

Store Olvan Trio 20 Tablet in a cool and dry place, away from direct sunlight, at a temperature below 30°C. Keep it out of the sight and reach of children.

Here are some frequently asked questions about OLVAN TRIO 20 MG TABLET:

What is OLVAN TRIO 20 MG TABLET used for?

OLVAN TRIO 20 MG TABLET is primarily used to treat hypertension, also known as high blood pressure, in adults. It is prescribed when a single medication is not sufficient to control blood pressure. By lowering high blood pressure, this medicine helps reduce the risk of serious complications such as heart attack, stroke, and kidney problems.

How does OLVAN TRIO 20 MG TABLET work?

OLVAN TRIO 20 MG TABLET is a combination medication containing three active ingredients: Olmesartan, Cilnidipine, and Chlorthalidone.

• Olmesartan is an angiotensin-II receptor blocker (ARB) that works by blocking a substance called angiotensin, which narrows blood vessels. By blocking it, Olmesartan helps widen the blood vessels, thereby reducing blood pressure.
• Cilnidipine is a calcium channel blocker. It relaxes the smooth muscles in blood vessel walls, causing them to widen and improve blood flow, which also helps to lower blood pressure.
• Chlorthalidone is a diuretic, or "water pill," that increases the excretion of excess water and salt from the body through urine. This reduces fluid accumulation and blood volume, contributing to lower blood pressure.

These three components work together through different mechanisms to effectively manage high blood pressure.

What is the usual dosage for OLVAN TRIO 20 MG TABLET?

OLVAN TRIO 20 MG TABLET is typically taken once a day, and it should be taken with food. The exact dose and duration will be determined by your doctor based on your specific condition and how your body responds to the medication. It is important to take it at the same time each day for consistency. Since it contains a diuretic, taking it within four hours of bedtime might be avoided to prevent frequent urination during the night.

What are the possible side effects of OLVAN TRIO 20 MG TABLET?

Common side effects include headache, dizziness, nausea, fatigue, stomach pain, constipation, or diarrhea. Other side effects can include flushing, palpitations, increased urination frequency, and lethargy. More serious side effects, though less common, can include severe dizziness or fainting, muscle cramps or irregular heartbeat (due to low potassium), yellowing of eyes or skin (signs of liver problems), sudden weight gain or swelling (signs of kidney issues), or allergic reactions like skin rash, itching, or trouble breathing. If any side effects persist, worsen, or if you experience any serious side effects, you should inform your doctor immediately.

Is OLVAN TRIO 20 MG TABLET safe during pregnancy or breastfeeding?

No, OLVAN TRIO 20 MG TABLET is generally not recommended for use during pregnancy, especially during the second and third trimesters, as it may cause harm to the unborn baby. If you become pregnant while taking this medicine, discontinue it and consult your doctor immediately. It is also not recommended for use in breastfeeding women, as its components may pass into breast milk with unknown effects on the baby.

Can OLVAN TRIO 20 MG TABLET be taken with other medications?

Several medications can interact with OLVAN TRIO 20 MG TABLET. It is crucial to inform your doctor about all other medicines, herbal preparations, and supplements you are taking.

• Not recommended with: Aliskiren (especially in diabetes or kidney disease), lithium (increased toxicity risk).
• Use with caution: NSAIDs (e.g., ibuprofen, naproxen) may reduce its blood pressure-lowering effect and worsen kidney function. Other blood pressure medications (e.g., ACE inhibitors), potassium supplements, or potassium-sparing diuretics may increase potassium levels. Medicines for heart failure (e.g., digoxin), certain antibiotics (e.g., rifampicin), and antifungals (e.g., itraconazole, miconazole) can also interact.
• Food interactions: Avoid consuming grapefruit juice as it may increase the medicine's levels in the body. It is also advisable to avoid potassium-rich foods (like potatoes, bananas, spinach, broccoli) during treatment.

What precautions should be taken while taking OLVAN TRIO 20 MG TABLET?

• Medical conditions: Inform your doctor if you have kidney disease (especially severe or anuria), liver disease, heart conditions (such as congestive heart failure, low blood pressure, or aortic stenosis), diabetes, gout, hyperuricemia, or electrolyte imbalances. Close monitoring of blood pressure, kidney function, and electrolyte levels is recommended.
• Dizziness: This medication can cause dizziness. Avoid driving or operating heavy machinery if you feel dizzy or sleepy.
• Dehydration: Drink plenty of fluids to stay hydrated, especially if you experience vomiting, diarrhea, or excessive sweating, as the medicine can cause dehydration and electrolyte disturbances.
• Alcohol: Avoid alcohol consumption as it may increase the risk of dizziness and other side effects.
• Diet: Maintain a diet low in salt.

What happens if a dose of OLVAN TRIO 20 MG TABLET is missed?

If you miss a dose of OLVAN TRIO 20 MG TABLET, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed one.

How should OLVAN TRIO 20 MG TABLET be stored?

OLVAN TRIO 20 MG TABLET should be stored in a cool and dry place, away from direct sunlight. It should be kept at temperatures between 10ºC to 25ºC or below 30ºC. Always keep this medicine out of the sight and reach of children.