Dynaduo M 10/1000mg Tab

Name

• Common Name: Dynaduo M 10/1000mg Tablet ER
• Brand Name: DYNADUO M
• Manufacturer: Mankind Pharma Ltd.

Composition Dynaduo M 10/1000mg Tablet ER is a combination medication containing three active ingredients:

• Empagliflozin (10mg)
• Linagliptin (5mg)
• Metformin (1000mg)

Uses Dynaduo M 10/1000mg Tablet ER is prescribed for adults with Type 2 diabetes mellitus to improve blood sugar control. It works by lowering glucose levels through multiple complementary mechanisms. When used regularly alongside a healthy diet and exercise, it can help reduce the risk of heart-related death and other long-term diabetes-related complications.

Dosage and Administration This medicine should be taken in the dose and duration as prescribed by a doctor. It can be taken with or without food, but for best results, it is advisable to take it at the same time every day. The tablet should be swallowed whole; do not chew, crush, or break it. Do not discontinue the medication without consulting a doctor, as abrupt cessation can lead to a spike in blood sugar levels.

Side Effects Common side effects may include:

• Upper respiratory tract infection
• Constipation
• Urinary tract infection
• Headache
• Stuffy or runny nose, sore throat
• Diarrhea
• Frequent urination, dizziness, or lightheadedness

If any of these side effects persist or worsen, it is important to consult a doctor.

Precautions

• Contraindications: Do not take Dynaduo M if you have severe kidney disease, certain types of metabolic acidosis, or known allergies to its ingredients. It is also not recommended for individuals with Type 1 diabetes.
• Pregnancy and Breastfeeding: Dynaduo M is considered unsafe to use during pregnancy and breastfeeding due to potential risks to the baby.
• Alcohol Consumption: It is unsafe to consume alcohol with Dynaduo M, as it can increase the risk of serious side effects like lactic acidosis or low blood sugar.
• Liver and Kidney Conditions: Use with caution in patients with severe kidney disease, and it is generally unsafe for those with liver disease and should be avoided.
• Other Conditions: Inform your doctor if you have kidney or liver problems, a urinary tract infection, history of pancreatitis, gallstones, low blood pressure, heart failure, high cholesterol, yeast infections, blocked or narrowed blood vessels, nerve problems, foot sores, or if you are taking diuretics.
• Interactions: Dynaduo M can interact with drugs affecting kidney function or blood sugar. Always inform your doctor about all medications you are taking.
• Monitoring: Your doctor may monitor kidney function, blood sugar levels, and vitamin B12 levels during treatment.

Storage Store Dynaduo M tablets at room temperature, ideally between 20°C to 25°C. Keep them away from moisture, excessive heat, and direct light. Ensure the medication is kept out of reach of children and pets. Do not use the medication past its expiration date.

What is Dynaduo M 10/1000MG Tablet used for?

Dynaduo M 10/1000MG Tablet is used to improve blood sugar control in adults with Type 2 diabetes mellitus. It also helps reduce the risk of heart-related death in adults with Type 2 diabetes who have established cardiovascular disease. This medicine is intended to be used as an adjunct to diet and exercise.

How does Dynaduo M 10/1000MG Tablet work?

This medicine contains three active ingredients: Empagliflozin (10mg), Linagliptin (5mg), and Metformin (1000mg).

• Empagliflozin works by blocking a protein in the kidneys called SGLT2 (sodium-glucose cotransporter 2), which normally reabsorbs sugar back into the blood. By blocking this protein, more sugar is removed from the body through urine, thereby lowering blood sugar levels.
• Linagliptin targets an enzyme called DPP-4 (dipeptidyl peptidase-4). By inhibiting DPP-4, it increases the levels of natural substances called incretins, which help the pancreas release more insulin (especially after meals) and decrease the amount of sugar the liver makes.
• Metformin (as Metformin Hydrochloride) reduces the amount of glucose produced by the liver, decreases glucose absorption from the intestines, and improves the body's sensitivity to insulin.

What is the usual dosage for Dynaduo M 10/1000MG Tablet?

The dosage of Dynaduo M 10/1000MG Tablet should be taken exactly as prescribed by your doctor. It is usually taken once daily, with or without food, preferably at the same time each day for best results. Do not chew, crush, or break the tablet.

What are the possible side effects of Dynaduo M 10/1000MG Tablet?

Common side effects may include upper respiratory tract infection, constipation, urinary tract infection, headache, nasal congestion (stuffy nose), sore throat, gastroenteritis, diarrhea, frequent urination, cough, rash, and itching. Low blood sugar (hypoglycemia) can occur, especially when taken with other diabetes medications. If any side effects persist or worsen, consult your doctor.

Is Dynaduo M 10/1000MG Tablet safe during pregnancy or breastfeeding?

Dynaduo M 10/1000MG Tablet is generally not recommended during pregnancy or while breastfeeding due to potential risks to the baby. If you are pregnant, planning to conceive, or breastfeeding, discuss with your doctor, who will weigh the benefits and potential risks and may adjust your diabetes treatment.

Can Dynaduo M 10/1000MG Tablet be taken with other medications?

Yes, Dynaduo M 10/1000MG Tablet can interact with other medications. It's crucial to inform your doctor about all medicines, supplements, or herbal products you are currently taking or plan to take. This medicine can interact with drugs affecting kidney function or blood sugar, such as insulin, sulfonylureas (e.g., glyburide, glimepiride), diuretics (e.g., furosemide), and certain antibiotics like rifampin.

What precautions should be taken while using Dynaduo M 10/1000MG Tablet?

• Alcohol: Avoid excessive alcohol intake, as it can increase the risk of serious side effects like lactic acidosis and low blood sugar.
• Kidney and Liver Conditions: Use with caution in patients with severe kidney disease, and it is generally avoided in patients with liver disease. Regular monitoring of kidney function is important.
• Dehydration: Stay well-hydrated, especially during physical activity or hot weather, to prevent fluid loss.
• Medical Conditions: This medicine is not recommended for Type 1 diabetes, diabetic ketoacidosis, or if you have certain types of metabolic acidosis.
• Before Surgery/Tests: Inform your doctor before any planned surgeries or contrast imaging tests, as you may need to temporarily stop the medication to prevent kidney problems.
• Allergies: Do not take if you have known allergies to empagliflozin, linagliptin, metformin, or any of its ingredients.

What happens if a dose of Dynaduo M 10/1000MG Tablet is missed?

If you miss a dose, take it as soon as you remember, unless it is nearly time for your next scheduled dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. Regularly missing doses can lead to elevated blood sugar levels.

How should Dynaduo M 10/1000MG Tablet be stored?

Store Dynaduo M 10/1000MG Tablet at room temperature, away from moisture, excessive heat, and direct light. Keep it out of reach of children and pets. Do not use the medication past its expiration date.