Zukanorm 100 Sr Tablet (15 Tab)

ZUKANORM 100 SR TABLET

ZUKANORM 100 SR TABLET is a medication manufactured by Mankind Pharma Ltd. primarily used for the management of type 2 diabetes mellitus. The "SR" in its name indicates a sustained-release formulation, designed to provide a gradual and consistent release of the medication over an extended period.

• Composition ZUKANORM 100 SR TABLET contains Vildagliptin 100 mg as its active ingredient. Vildagliptin belongs to a class of medicines called dipeptidyl peptidase-4 (DPP-4) inhibitors. It works by preventing the breakdown of incretin hormones, which are released after meals and stimulate the pancreas to release more insulin. This action helps to lower blood sugar levels and reduce glucagon production by the liver.

• Uses ZUKANORM 100 SR TABLET is prescribed to control high blood sugar levels in adults with type 2 diabetes mellitus. It is used alongside a healthy diet and regular exercise to improve glycemic control. This medication can be used as a standalone treatment or in combination with other antidiabetic agents, such as metformin or insulin, especially when diet and exercise alone are insufficient. Effective blood sugar management helps prevent serious complications of diabetes, including kidney damage, eyesight loss, nerve damage, and an increased risk of heart attack or stroke.

• Dosage and Administration ZUKANORM 100 SR TABLET is typically taken orally once daily, usually in the morning. It can be taken with or without food, but it is recommended to take it at the same time each day to maintain consistency. The tablet should be swallowed whole with water and should not be chewed, crushed, or broken. Dosage adjustments are made by a healthcare professional based on individual blood glucose response and tolerability.

• Side Effects Common side effects of ZUKANORM 100 SR TABLET may include hypoglycemia (low blood sugar levels), headache, dizziness, fatigue, nausea, tremors, and nasopharyngitis (infection of the nose and throat with the common cold). Other possible side effects include abdominal pain, diarrhea, constipation, and joint pain. If side effects persist or worsen, medical attention should be sought.

• Precautions Before taking ZUKANORM 100 SR TABLET, inform your doctor about any allergies, pre-existing conditions (especially kidney disease, liver disease, heart disease, or pancreas problems like pancreatitis), or other medications (including over-the-counter drugs and herbal supplements) you are taking.

  • Alcohol: Alcohol consumption with ZUKANORM 100 SR TABLET can increase the risk of low blood sugar levels and lactic acidosis, a serious side effect.
  • Pregnancy & Breastfeeding: ZUKANORM 100 SR TABLET is generally not recommended during pregnancy (Category B pregnancy drug) and breastfeeding. Consult a doctor before use if pregnant or breastfeeding.
  • Driving: The medication may cause dizziness, affecting alertness and vision. Avoid driving or operating machinery until you know how it affects you.
  • Other Conditions: It is not recommended for individuals with type 1 diabetes, diabetic ketoacidosis, severe kidney or liver disease. Regular monitoring of blood sugar levels and kidney and liver function is essential during treatment.

• Storage Store ZUKANORM 100 SR TABLET in a cool and dry place, away from direct sunlight, heat, and moisture. Keep it below 30°C and out of the reach of children.

What is ZUKANORM 100 SR TABLET used for?

ZUKANORM 100 SR TABLET is primarily used to treat Type 2 Diabetes Mellitus in adults. It helps manage and control high blood sugar levels, especially when diet and exercise alone are not sufficient. It can be used as a standalone medication or in combination with other antidiabetic drugs or insulin. Effective blood sugar control helps prevent serious complications of diabetes such as kidney damage, eyesight loss, nerve problems, and increased risk of heart attack or stroke.

How does ZUKANORM 100 SR TABLET work?

ZUKANORM 100 SR TABLET contains Vildagliptin, which belongs to a class of medicines called Dipeptidyl Peptidase-4 (DPP-4) inhibitors. It works by preventing the breakdown of "incretin" hormones, which are naturally released after a meal. Increased levels of incretin hormones stimulate the pancreas to release more insulin and reduce the production of glucagon by the liver, thereby lowering elevated blood sugar levels.

What is the usual dosage for ZUKANORM 100 SR TABLET?

ZUKANORM 100 SR TABLET is typically taken once daily, usually in the morning. It can be taken with or without food, but it's advisable to take it at a fixed time each day for consistent results. The exact dosage and duration will be determined by your doctor based on your medical condition and response to treatment. Do not chew, crush, or break the sustained-release (SR) tablet.

What are the possible side effects of ZUKANORM 100 SR TABLET?

Common side effects may include low blood sugar levels (hypoglycemia), headache, dizziness, nausea, fatigue, tremors, excessive sweating, and nasopharyngitis (common cold-like symptoms). Most of these side effects are usually mild and resolve over time. However, if any side effects persist or worsen, you should consult your doctor. Serious but rare side effects can include acute pancreatitis and severe allergic reactions such as anaphylaxis, angioedema, or Stevens-Johnson syndrome.

Is ZUKANORM 100 SR TABLET safe during pregnancy or breastfeeding?

ZUKANORM 100 SR TABLET is generally not recommended during pregnancy and is considered a Category B pregnancy drug. Animal studies suggest potential harm to the developing baby, and it may have some side effects during pregnancy. Its excretion into breast milk is unknown, and it is not recommended for breastfeeding mothers. Always consult your doctor if you are pregnant, planning a pregnancy, or breastfeeding before taking this medication.

Can ZUKANORM 100 SR TABLET be taken with other medications?

ZUKANORM 100 SR TABLET can be used in combination with other antidiabetic medications like metformin, sulfonylureas, or thiazolidinediones, and also with insulin, to achieve optimal blood sugar control. However, caution is advised when taking it with certain medications, including digoxin (a heart medicine), warfarin (an anticoagulant), some cardiac drugs (e.g., captopril, enalapril), simvastatin (for cholesterol), thiazide diuretics, and corticosteroids, as interactions may occur. It's crucial to inform your doctor about all medications, supplements, and herbal products you are currently taking to avoid potential interactions.

What precautions should be taken while using ZUKANORM 100 SR TABLET?

This medication is not for individuals with Type 1 diabetes or diabetic ketoacidosis. It should be used with caution, or avoided, in patients with severe kidney or liver disease, heart disease, or a history of pancreatitis. Regular monitoring of blood sugar levels, kidney function, and liver function is important during treatment. Alcohol consumption should be limited or avoided as it can affect blood sugar levels and increase the risk of low blood sugar. Be aware of symptoms of low blood sugar (hypoglycemia) such as sweating, dizziness, and tremors, and carry a source of quick-acting sugar like glucose tablets or fruit juice. ZUKANORM 100 SR TABLET is not recommended for use in children below 18 years of age.

What happens if a dose of ZUKANORM 100 SR TABLET is missed?

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for the missed one.

How should ZUKANORM 100 SR TABLET be stored?

ZUKANORM 100 SR TABLET should be stored in a cool and dry place, away from direct sunlight, moisture, and heat. The ideal room temperature for storage is below 25°C or 30°C. Keep the medicine out of the sight and reach of children.