Gabantip At 100 Mg Tablet (10 Tab)

GABANTIP AT 100 MG TABLET is a prescription medicine manufactured by SUN PHARMA LABORATORIES LTD., primarily used for the management of neuropathic pain.

• Name: GABANTIP AT 100 MG TABLET (Brand Name: Gabantip AT)
• Composition: Each tablet contains Gabapentin 100 mg and Amitriptyline 10 mg. Gabapentin is an anticonvulsant that works by modulating calcium channel activity in nerve cells, while Amitriptyline is a tricyclic antidepressant that increases levels of chemical messengers like serotonin and noradrenaline in the brain, thereby preventing pain signals.
• Uses: GABANTIP AT 100 MG TABLET is prescribed for the treatment of long-lasting (chronic) neuropathic pain caused by nerve damage. This includes conditions such as:
  • Postherpetic neuralgia (pain after shingles infection).
  • Diabetic neuropathy (tingling, numbness, and shooting pain due to diabetic nerve damage).
  • Fibromyalgia (generalized muscle pain and tenderness).
  • It may also be used to treat restless leg syndrome and certain types of seizures.
• Dosage and Administration: This medicine should be taken orally with or without food, preferably at bedtime. It is advised to take it at the same time each day to maintain consistent medicine levels. Swallow the tablet whole; do not chew, crush, or break it. The dosage and duration should be as prescribed by a doctor, and it should not be stopped suddenly as it may lead to withdrawal symptoms or increased seizure frequency.
• Side Effects:
  • Common: Dizziness, sleepiness, tiredness, headache, nausea, vomiting, blurred vision, dry mouth, constipation, uncoordinated body movements, weight gain, and difficulty in urination.
  • Serious: Mood changes, suicidal tendencies, severe allergic reactions (skin reactions, breathing difficulties, swelling, low blood pressure), increased heartbeat, weakness, unsteadiness, reduced coordination, confusion, aggression, agitation, irrational thinking, double vision, uncontrollable jerky eye movements, frequent infections, fever, severe chills, sore throat, mouth ulcers, acute pancreatitis, unusual bruising or bleeding, and muscle pain.
• Precautions:
  • Avoid consuming alcohol as it can increase dizziness and sleepiness.
  • Not recommended during pregnancy, especially in the last few months, and generally considered unsafe during breastfeeding.
  • May cause drowsiness and blurred vision, so avoid driving or operating machinery until you know how the medicine affects you.
  • Use with caution in patients with heart, kidney, or liver problems, nervous system disorders, respiratory disorders, or prostate issues.
  • Antacids should be avoided 2 hours before or after taking this medicine as they can interfere with absorption.
  • Patients should be monitored for suicidal thoughts or behavior.
  • Do not stop taking suddenly; the dose should be gradually tapered under medical supervision.
• Storage: Store in a cool and dry place, away from direct sunlight and moisture. Keep out of sight and reach of children.

GABANTIP AT 100 MG TABLET: Frequently Asked Questions

GABANTIP AT 100 MG TABLET is a combination medication containing Gabapentin and Amitriptyline, primarily used to manage neuropathic pain. Here are some of the most frequently asked questions about this medicine.

What is GABANTIP AT 100 MG TABLET used for?

GABANTIP AT 100 MG TABLET is used to treat long-lasting (chronic) neuropathic pain, which is pain caused by nerve damage. This can stem from conditions such as diabetes, shingles (postherpetic neuralgia), or spinal cord injury. It helps reduce pain and associated symptoms like mood changes, sleep problems, and tiredness. It may also be prescribed for fibromyalgia.

How does GABANTIP AT 100 MG TABLET work?

This medicine combines two active ingredients: Gabapentin and Amitriptyline. Gabapentin, an anti-convulsant, works by modulating calcium channel activity in nerve cells, which decreases the pain signals. Amitriptyline, a tricyclic antidepressant, increases the levels of chemical messengers (serotonin and noradrenaline) in the brain, thereby stopping the movement of pain signals. Together, they calm damaged or overactive nerves, reducing pain sensation.

What is the usual dosage of GABANTIP AT 100 MG TABLET?

GABANTIP AT 100 MG TABLET typically contains 100 mg of Gabapentin and 10 mg of Amitriptyline. The dosage and duration of treatment are determined by your doctor based on your medical condition and should be taken as prescribed. It is often recommended to take it at the same time each day, preferably at bedtime, with or without food.

What are the possible side effects of GABANTIP AT 100 MG TABLET?

Common side effects include sleepiness, dizziness, tiredness, constipation, difficulty in urination, weight gain, uncoordinated body movements, increased heart rate, sudden lowering of blood pressure on standing (orthostatic hypotension), blurred vision, and dry mouth. More serious but rare side effects can include unusual changes in mood or behavior (such as restlessness or depression), suicidal thoughts, severe allergic reactions (e.g., skin rash, hives, swelling of face/throat), and breathing problems. If you experience any severe or persistent side effects, contact your doctor immediately.

Is GABANTIP AT 100 MG TABLET safe during pregnancy or breastfeeding?

GABANTIP AT 100 MG TABLET is generally not recommended during pregnancy, especially in the last few months, as animal studies have shown harmful effects on the developing baby and there's a risk of withdrawal symptoms in newborns. It should only be used if the potential benefits outweigh the risks, as determined by your doctor.

During breastfeeding, GABANTIP AT 100 MG TABLET is probably unsafe to use as it may pass into breast milk and potentially harm the baby. However, Gabapentin alone is considered compatible with breastfeeding with caution and infant monitoring, as only small amounts transfer to breast milk. Always consult your doctor before taking this medication if you are pregnant, planning pregnancy, or breastfeeding.

Can GABANTIP AT 100 MG TABLET be taken with other medications?

It is crucial to inform your doctor about all other medicines, supplements, or herbal products you are currently taking to avoid potential interactions.

• Antacids: Avoid taking antacids within 2 hours before or after taking GABANTIP AT 100 MG TABLET, as they can interfere with its absorption.
• Alcohol: Do not consume alcohol with this medicine, as it can intensify dizziness and sleepiness.
• MAOIs: This medicine should not be taken with monoamine oxidase inhibitors (MAOIs) or within 14 days of stopping them, due to the increased risk of serious side effects.
• Other CNS Depressants: Caution is advised with other medications that cause drowsiness or slow brain activity, such as opioids, benzodiazepines, certain antidepressants, antihistamines, and muscle relaxants, as this combination can lead to dangerously slowed breathing.
• Heart and Liver Conditions: Inform your doctor if you have heart, kidney, or liver problems, as dose adjustments or alternative treatments may be necessary.

What precautions should be taken while using GABANTIP AT 100 MG TABLET?

• Driving and Machinery: This medicine can cause dizziness, drowsiness, and blurred vision. Avoid driving or operating heavy machinery until you know how it affects you.
• Sudden Discontinuation: Do not stop taking GABANTIP AT 100 MG TABLET suddenly, even if you feel better. Abruptly stopping can lead to withdrawal symptoms (e.g., anxiety, sleeping difficulties, nausea, pain) and, if you have epilepsy, can increase the risk of seizures. Your doctor will guide you on gradually reducing the dose if needed.
• Underlying Conditions: Use with caution if you have kidney or liver disease, heart conditions (such as a recent heart attack or arrhythmias), bipolar disorder, glaucoma, or prostate problems.
• Mood Changes: Report any unusual changes in mood or behavior, or suicidal thoughts, to your doctor immediately.
• Sun Sensitivity: This medicine may make you more prone to sunburns, so use sunscreen and wear protective clothing when outdoors.

What happens if a dose of GABANTIP AT 100 MG TABLET is missed?

If you miss a dose, take it as soon as you remember. However, if it's almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. It is important to complete the full course of treatment as advised by your doctor.

How should GABANTIP AT 100 MG TABLET be stored?

Store GABANTIP AT 100 MG TABLET in a cool, dry place, away from direct sunlight and moisture. Keep it out of sight and reach of children.