Signoflam Th 8

SIGNOFLAM TH 8 Tablet

SIGNOFLAM TH 8 Tablet is a combination medication manufactured by Lupin Ltd. It is designed to provide relief from various types of acute inflammatory and painful conditions associated with muscle spasms.

• Name:

  • Brand Name: SIGNOFLAM TH 8 Tablet
  • Manufacturer: Lupin Ltd.

• Composition:

  • Active Ingredients: Each tablet contains:
    • Aceclofenac (100 mg)
    • Paracetamol / Acetaminophen (325 mg)
    • Thiocolchicoside (8 mg)
  • Aceclofenac is a non-steroidal anti-inflammatory drug (NSAID) that inhibits the production of pain and inflammation-causing prostaglandins.
  • Paracetamol acts as an analgesic and antipyretic, reducing pain and fever.
  • Thiocolchicoside is a muscle relaxant that works on the central nervous system to relieve muscle stiffness and improve muscle movements.

• Uses: SIGNOFLAM TH 8 Tablet is primarily used for the management of acute musculoskeletal pain and inflammation. It is prescribed for conditions such as:

  • Lower back pain
  • Osteoarthritis
  • Rheumatoid arthritis
  • Ankylosing spondylitis (a type of arthritis affecting the spine)
  • Muscle spasms due to injury
  • Neck and shoulder pain
  • Sciatica (nerve pain)
  • Degenerative vertebral disorders
  • Post-operative pain

• Dosage and Administration:

  • Take SIGNOFLAM TH 8 Tablet orally as advised by your physician.
  • It is generally recommended to take the tablet with or after meals to minimize stomach upset.
  • Swallow the tablet whole with a glass of water; do not chew, crush, or break it.
  • The dosage and duration of treatment will be determined by your doctor based on your age, body weight, and the severity of your condition.

• Side Effects:

  • Common Side Effects: Dyspepsia (indigestion), diarrhoea, abdominal pain, nausea, vomiting, dizziness, sleepiness/drowsiness, rash, pruritus (itching), oedema (swelling), heartburn, loss of appetite, dryness in the mouth, gas, constipation, mouth ulcers, increased liver enzymes, and vision problems.
  • Serious Side Effects (seek immediate medical attention if experienced): Severe allergic reactions (symptoms include fever, difficulty breathing, wheezing, stomach pain, vomiting, swelling of the face and throat), severe skin reactions (e.g., Stevens-Johnson syndrome, toxic epidermal necrolysis), meningitis, kidney failure, gastrointestinal bleeding (e.g., blood in stools or vomiting blood), blood disorders, and liver problems.

• Precautions:

  • Pregnancy and Breastfeeding: Not recommended during pregnancy unless benefits outweigh risks, and components may be excreted in breast milk. Consult your doctor.
  • Alcohol: Avoid or limit alcohol consumption as it may increase drowsiness and the risk of stomach bleeding and liver damage.
  • Medical Conditions: Use with caution or avoid if you have a history of severe heart problems, peptic ulcers, intestinal bleeding, bleeding disorders, severe liver or kidney impairment, high blood pressure, diabetes, asthma, or inflammatory bowel disease.
  • Driving and Operating Machinery: May cause dizziness and drowsiness; avoid driving or operating heavy machinery if you experience these effects.
  • Children: Not recommended for children below 16-18 years of age due to uncertain safety and efficacy.
  • Elderly Patients: Use with caution in elderly patients (above 65 years) as they may be more prone to side effects.
  • Drug Interactions: Inform your doctor about all other medications you are taking, especially other NSAIDs, anticoagulants, corticosteroids, antidiabetic medications, and certain immunosuppressants, to avoid potential interactions.

• Storage:

  • Store in a cool, dry place below 30°C.
  • Keep away from direct sunlight and excessive moisture.
  • Ensure the medicine is kept out of sight and reach of children.

Here are frequently asked questions about SIGNOFLAM TH 8, a medicine manufactured by LUPIN LTD-ENDEAVOUR DIV:

What is SIGNOFLAM TH 8 used for?

SIGNOFLAM TH 8 is a combination medicine primarily used to alleviate various types of acute musculoskeletal pain and inflammation. It is effective in treating conditions such as lower back pain, muscle spasms, osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, neck and shoulder pain, sciatica, degenerative vertebral disorders, and post-operative pain.

How does SIGNOFLAM TH 8 work?

SIGNOFLAM TH 8 contains three active ingredients: Thiocolchicoside, Aceclofenac, and Paracetamol. Thiocolchicoside acts as a muscle relaxant by working on the centers in the brain and spinal cord to relieve muscle stiffness and improve muscle movements. Aceclofenac is a non-steroidal anti-inflammatory drug (NSAID) that reduces pain and inflammation by blocking the production of chemical messengers (prostaglandins) that cause these symptoms. Paracetamol acts as an analgesic (pain reliever) and antipyretic (fever reducer) by blocking the release of specific chemical messengers responsible for pain and fever. This combined action helps in easing discomfort and improving muscle movement.

What is the usual dosage of SIGNOFLAM TH 8?

The dosage and duration of SIGNOFLAM TH 8 should be determined by your doctor based on your specific medical condition, age, body weight, and response to treatment. It is generally recommended to swallow the tablet whole with a glass of water, without chewing, crushing, or breaking it. To avoid stomach upset, it is advisable to take SIGNOFLAM TH 8 with food, either during or after meals. Do not exceed the recommended dose.

What are the possible side effects of SIGNOFLAM TH 8?

Common side effects may include nausea, vomiting, stomach pain, diarrhea, loss of appetite, heartburn, dryness in the mouth, dizziness, drowsiness, gas, constipation, mouth ulcers, rashes, itching, and allergic skin reactions. More serious but less common side effects can include severe allergic reactions, skin conditions like Stevens-Johnson syndrome, kidney failure, gastrointestinal bleeding, vomiting blood, and liver problems. If any side effects persist or worsen, it is essential to inform your doctor promptly.

Is SIGNOFLAM TH 8 safe during pregnancy or breastfeeding?

SIGNOFLAM TH 8 is generally not recommended during pregnancy, especially in the first and third trimesters, as components of this medicine may cause abnormalities in the unborn baby. It is also not recommended during breastfeeding, as its components may be excreted in breast milk and could have undesirable effects on the infant. Always consult your healthcare provider before using this medication if you are pregnant, planning to conceive, or breastfeeding.

Can SIGNOFLAM TH 8 be taken with other medications?

It is crucial to inform your doctor about all other medications you are taking, including over-the-counter drugs, herbal supplements, and vitamins, to avoid potential drug interactions. SIGNOFLAM TH 8 may interact with anticoagulants (blood thinners like warfarin), other non-steroidal anti-inflammatory drugs (NSAIDs like aspirin or ibuprofen), and corticosteroids, potentially increasing the risk of stomach issues or bleeding. It can also interact with certain antidiabetic medications, immunosuppressants (cyclosporin, tacrolimus), and other drugs like zidovudine, lithium, methotrexate, and mifepristone.

What precautions should be taken while using SIGNOFLAM TH 8?

Avoid alcohol consumption while taking SIGNOFLAM TH 8 as it can increase drowsiness, dizziness, and the risk of stomach bleeding and liver damage. This medication may cause drowsiness and dizziness, so avoid driving or operating machinery if you experience these side effects. It is not recommended for children due to uncertain safety and efficacy. Exercise caution if you have pre-existing medical conditions such as liver or kidney problems, heart issues, high blood pressure, diabetes, asthma, stomach ulcers, or bleeding disorders. Elderly patients should use this medicine with caution as they may be more prone to side effects.

What happens if a dose of SIGNOFLAM TH 8 is missed?

If you miss a dose of SIGNOFLAM TH 8, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed one, as this can increase the risk of side effects.

How should SIGNOFLAM TH 8 be stored?

Store SIGNOFLAM TH 8 in a cool, dry place below 30°C (or between 20-25°C), away from direct sunlight and excessive moisture. Ensure the medicine is kept out of the sight and reach of children. Always check the expiry date and use the medicine before it expires.