Nexipride 25

NEXIPRIDE 25 by SUN PHARMA VV

Name

• Brand Name: NEXIPRIDE 25
• Common Name: Levosulpiride Tablets 25 mg

Composition NEXIPRIDE 25 contains Levosulpiride at a strength of 25 mg as its active ingredient.

Uses NEXIPRIDE 25 is primarily used to manage various gastrointestinal disorders. These include:

• Gastroesophageal Reflux Disease (GERD), which involves heartburn and acid reflux.
• Irritable Bowel Syndrome (IBS), addressing symptoms like abdominal pain, constipation, and diarrhea.
• Dyspepsia (indigestion), including non-ulcer dyspepsia, bloating, and abdominal discomfort.
• Nausea and vomiting.
• Delayed gastric emptying, such as in diabetic gastroparesis.

Additionally, it is used to treat psychotic disorders like somatic symptom disorders and chronic schizophrenia with negative symptoms, as Levosulpiride also works by blocking dopamine receptors in the brain to improve mood, behavior, and thoughts.

Dosage and Administration NEXIPRIDE 25 should be taken orally as advised by your doctor, typically 30 minutes before food, 1 to 3 times daily. It is advisable to take the medicine at the same time each day to maintain a consistent level in the body. The tablet should be swallowed whole with a glass of water and not crushed, chewed, or broken. Do not stop taking this medicine without consulting your doctor.

Side Effects Common side effects may include:

• Dizziness, drowsiness, sleepiness, and fatigue.
• Headache.
• Constipation.
• Weight gain.
• Irregular menstrual periods, breast tenderness, or swelling of breasts in men (gynecomastia).
• Increased salivation and decreased libido.

Serious side effects, though rare, can include muscle stiffness or shaking, high fever (possible neuroleptic malignant syndrome), seizures, and abnormal heart rhythm. Report any concerning symptoms to your doctor immediately.

Precautions

• Alcohol: Avoid consuming alcohol as it can enhance side effects like dizziness and sedation.
• Pregnancy and Breastfeeding: NEXIPRIDE 25 is generally not recommended during pregnancy or breastfeeding due to potential risks. Consult your doctor.
• Driving: This medicine may cause dizziness and drowsiness, so avoid driving or operating machinery until you know how it affects you.
• Medical Conditions: Inform your doctor if you have epilepsy, a history of seizures, Parkinson's disease, high blood pressure, breast cancer, liver or kidney problems, gastrointestinal bleeding/blockage/perforations, dementia, heart problems, or blood clot problems.
• Children: Not recommended for children as safety and effectiveness have not been established.
• Drug Interactions: Medications that neutralize stomach acidity (containing aluminum and magnesium hydroxide), muscle relaxants, and certain painkillers may alter the effectiveness of NEXIPRIDE 25. Discuss all current medications with your doctor to avoid interactions.

Storage Keep NEXIPRIDE 25 out of reach and sight of children. Store below 30°C, protected from moisture and light. Dispose of expired or unused medication appropriately.

NEXIPRIDE 25 by SUN PHARMA VV is a medication containing Levosulpiride, primarily used to treat various gastrointestinal disorders and certain mental health conditions.

What is NEXIPRIDE 25 used for?

NEXIPRIDE 25 is prescribed for the management of gastroesophageal reflux disease (GERD), irritable bowel syndrome (IBS), dyspepsia (indigestion), nausea, and vomiting. It is also used to treat somatic symptom disorders and chronic schizophrenia with negative symptoms. Additionally, it can help with discomfort and pain in the upper abdomen due to acid reflux, non-ulcer dyspepsia, and delayed gastric emptying in diabetic patients (diabetic gastroparesis).

How does NEXIPRIDE 25 work?

NEXIPRIDE 25 contains Levosulpiride, which acts in a dual manner. It increases the pressure of the inferior oesophageal sphincter, preventing the backflow of food and acid from the stomach into the esophagus. It also enhances gastrointestinal motility, improving the movement of food through the digestive tract. Furthermore, it works by blocking certain dopamine receptors in the brain, which can help improve mood, behavior, and thoughts, particularly in conditions like schizophrenia.

What is the usual dosage for NEXIPRIDE 25?

The dosage of NEXIPRIDE 25 is determined by your doctor based on your specific medical condition, age, and response to the treatment. A common dosage is 25 mg, taken three times daily. It should generally be taken 30 minutes before food. Swallow the tablet whole with a glass of water; do not crush, break, or chew it. For consistent medication levels in your body, try to take it at the same time each day.

What are the possible side effects of NEXIPRIDE 25?

Common side effects include dizziness, sleepiness or drowsiness, weakness, headache, fatigue, constipation, abdominal pain, irregular menstrual periods, decreased sexual desire, breast tenderness or enlargement, increased salivation, and weight gain. Less common but more serious side effects can include tremors, muscle stiffness, high fever (possible neuroleptic malignant syndrome), seizures, and abnormal heart rhythm. If you experience persistent or severe side effects, consult your doctor.

Is NEXIPRIDE 25 safe during pregnancy or breastfeeding?

NEXIPRIDE 25 is generally not recommended and is considered unsafe or contraindicated during pregnancy due to potential risks to the developing baby. Similarly, it is probably unsafe to use while breastfeeding, as the medication may pass into breast milk. Always consult your doctor if you are pregnant, planning to become pregnant, or breastfeeding before taking this medicine.

Can NEXIPRIDE 25 be taken with other medications?

NEXIPRIDE 25 can interact with several other medications. It may interact with painkillers, anticholinergic drugs, certain heart medicines (like those prolonging the QT interval or affecting heart rhythm), medications causing electrolyte disturbances, narcotics, and antacids containing aluminum and magnesium hydroxide, which might reduce its effectiveness. Antipsychotics, antidepressants, and opioids can also enhance its side effects. However, it can generally be taken safely with omeprazole. Always inform your doctor about all prescription, over-the-counter medicines, supplements, and herbal products you are currently taking to avoid potential interactions.

What precautions should be taken while using NEXIPRIDE 25?

Avoid consuming alcohol while taking NEXIPRIDE 25, as it can increase drowsiness and other unpleasant side effects. Since this medicine can cause dizziness and sleepiness, do not drive or operate heavy machinery until you understand how it affects you. NEXIPRIDE 25 is not recommended for children as its safety and effectiveness have not been established. Inform your doctor about any pre-existing conditions such as epilepsy, Parkinson's disease, breast cancer, liver or kidney problems, heart conditions, or gastrointestinal bleeding/blockages. Do not stop taking NEXIPRIDE 25 suddenly without consulting your doctor, as this may lead to a recurrence of symptoms.

What happens if a dose of NEXIPRIDE 25 is missed?

If you miss a dose of NEXIPRIDE 25, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to compensate for the missed one.

How should NEXIPRIDE 25 be stored?

Store NEXIPRIDE 25 in a cool, dry place, typically below 30°C, away from direct sunlight and moisture. Keep the medication out of reach and sight of children and pets.