Rozucor Ez

ROZUCOR EZ

ROZUCOR EZ by TORRENT PHARMACEUTICALS LTD is a combination medication primarily prescribed for the management of high cholesterol levels.

Composition ROZUCOR EZ contains two active ingredients:

• Rosuvastatin: An HMG-CoA reductase inhibitor (statin) that works by blocking liver enzymes responsible for cholesterol production, thereby reducing "bad" cholesterol (LDL) and increasing "good" cholesterol (HDL) levels.
• Ezetimibe: A sterol absorption inhibitor that prevents the absorption of cholesterol from the intestines. Common strengths include Rosuvastatin 10mg + Ezetimibe 10mg, Rosuvastatin 20mg + Ezetimibe 10mg, and Rosuvastatin 40mg + Ezetimibe 10mg.

Uses This medicine is used for:

• Treating hyperlipidemia (high cholesterol), including primary hyperlipidemia and mixed dyslipidemia.
• Lowering LDL cholesterol and triglycerides.
• Increasing HDL cholesterol.
• Preventing cardiovascular events such as heart attack and stroke.
• Managing familial hypercholesterolemia.

Dosage and Administration Typically, ROZUCOR EZ is taken once daily, orally, with or without food. It should be swallowed whole without crushing, chewing, or breaking. For optimal benefits, it's recommended to take it at the same time each day. Dosage adjustments are made by a doctor based on individual cholesterol levels and response to treatment. Do not discontinue the medication without consulting your doctor.

Side Effects Common side effects may include:

• Headache, dizziness, weakness, fatigue
• Nausea, abdominal pain, diarrhea, constipation, gas
• Muscle pain, joint pain, back pain
• Upper respiratory tract infection, common cold More serious, though rare, side effects that require immediate medical attention include signs of liver damage (e.g., yellowing skin/eyes, dark urine), severe muscle pain or weakness (rhabdomyolysis), or severe allergic reactions.

Precautions ROZUCOR EZ is contraindicated in individuals with allergies to its components, active liver disease, severe kidney problems, muscle disorders, or those who are pregnant or breastfeeding. Caution is advised for patients with liver or kidney problems, diabetes, thyroid disorders, or a history of muscle issues. Regular monitoring of liver function, cholesterol levels, and blood sugar is recommended during treatment. Avoid excessive alcohol consumption. Inform your doctor about all other medications, supplements, and herbal products being taken to prevent potential drug interactions.

Storage Store ROZUCOR EZ in a cool, dry place away from direct sunlight. Keep it in an airtight container at room temperature (between 10ºC and 25ºC or below 30ºC) and out of the sight and reach of children. Protect from moisture and light.

ROZUCOR EZ is a combination medicine manufactured by Torrent Pharmaceuticals Ltd. It contains two active ingredients: Rosuvastatin and Ezetimibe.

What is ROZUCOR EZ used for?

ROZUCOR EZ is primarily used to treat high cholesterol levels (hypercholesterolemia and mixed dyslipidemia). It helps to lower "bad" cholesterol (LDL) and triglycerides, while also increasing "good" cholesterol (HDL). This medication is also used to reduce the risk of cardiovascular events such as heart attacks and strokes. It can also be prescribed for homozygous familial hypercholesterolemia.

How does ROZUCOR EZ work?

ROZUCOR EZ works through a dual mechanism due to its two components:

• Rosuvastatin: This is a statin that blocks an enzyme in the liver (HMG-CoA reductase) responsible for producing cholesterol, thereby reducing the amount of cholesterol the liver makes.
• Ezetimibe: This component works in the small intestine to prevent the absorption of cholesterol from dietary sources, thus decreasing the amount of cholesterol that enters the bloodstream. Together, these actions provide a more significant reduction in overall cholesterol levels.

What is the usual dosage of ROZUCOR EZ?

The usual dosage of ROZUCOR EZ is one tablet daily, taken orally with or without food. It is crucial to follow your doctor's instructions precisely, as the dosage may vary based on your cholesterol levels and response to treatment. Do not crush, break, or chew the tablet.

What are the possible side effects of ROZUCOR EZ?

Common side effects of ROZUCOR EZ can include headache, muscle pain, weakness, joint pain, abdominal pain, diarrhea, nausea, dizziness, constipation, and symptoms of the common cold or upper respiratory tract infection. More serious side effects, though rare, can include unexplained muscle pain, severe tiredness, yellowing of the skin or eyes (signs of liver problems), dark urine, skin rashes or blisters, or swelling in your face or throat. If you experience any severe or persistent side effects, you should consult your doctor immediately.

Is ROZUCOR EZ safe during pregnancy or breastfeeding?

No, ROZUCOR EZ is not recommended during pregnancy as it may harm the unborn baby. Women of childbearing age should use effective contraception while taking this medicine. It is also not recommended during breastfeeding because it is unknown if the medicine passes into human milk and could harm the baby. Always inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding.

Can ROZUCOR EZ be taken with other medications?

ROZUCOR EZ can interact with certain medications, including:

• Immunosuppressants: Medicines like ciclosporin may increase the concentration of rosuvastatin and ezetimibe in your blood, increasing the risk of side effects.
• Fibrates: Medicines such as gemfibrozil can increase the effect of rosuvastatin, potentially causing muscle damage.
• Blood thinners (anticoagulants): Medicines like warfarin may have altered effects.
• Antacids: Medicines containing aluminum and magnesium hydroxide can reduce the absorption of rosuvastatin.
• Antiviral medicines: Used for HIV and Hepatitis C (e.g., sofosbuvir/velpatasvir/voxilaprevir combinations).

Always inform your doctor about all the medicines, supplements, or herbal products you are currently taking or might take to avoid possible interactions.

What precautions should be taken?

Before taking ROZUCOR EZ, inform your doctor if you have:

• Liver or kidney problems.
• Diabetes (regular monitoring of blood sugar levels may be recommended).
• Thyroid gland problems.
• Musculoskeletal disorders (like myopathy and rhabdomyolysis) or a family history of muscle problems.
• Severe lung disease.
• Allergies to ezetimibe, rosuvastatin, or any other ingredients of the tablet.

Regular monitoring of liver enzyme levels is recommended during treatment. Avoid excessive alcohol consumption as it can increase the risk of liver problems. Lifestyle modifications such as regular exercise and a healthy, low-fat diet are also important.

What happens if a dose is missed?

If you miss a dose of ROZUCOR EZ, take it as soon as you remember. However, if it's almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to compensate for the missed one.

How should it be stored?

ROZUCOR EZ should be stored in a cool and dry place, away from direct sunlight and moisture, and out of the sight and reach of children. It is typically stored at room temperature (10°C to 25°C or below 30°C).