Statpure Ez 10 Tab

STATPURE EZ 10 Tablet

Name: Statpure EZ 10 Tablet (Brand name).

Composition: STATPURE EZ 10 Tablet contains a combination of two active ingredients:

• Rosuvastatin (10 mg): An HMG-CoA reductase inhibitor (statin).
• Ezetimibe (10 mg): A sterol absorption inhibitor.

Uses: STATPURE EZ 10 Tablet is primarily used to manage high cholesterol levels in the blood. It is prescribed for:

• Lowering high levels of "bad" LDL cholesterol and triglycerides.
• Increasing levels of "good" HDL cholesterol.
• Treating hyperlipidemia and mixed dyslipidemia.
• Reducing the risk of cardiovascular diseases, including heart attack, stroke, and heart-related chest pain (angina).
• Supporting cholesterol control alongside diet changes and exercise.

Dosage and Administration: The recommended dose is typically 10 mg once daily. It should be taken by mouth, with or without food, as advised by a doctor. It is important to follow the doctor's instructions on dosage and timing and not to change the dose without consulting a healthcare professional.

Side Effects: Common side effects of STATPURE EZ 10 Tablet may include:

• Nausea.
• Muscle pain (myalgia), weakness, tiredness (asthenia).
• Joint pain.
• Headache.
• Abdominal pain, diarrhoea.
• Upper respiratory tract infection, common cold.
• Dizziness.

Serious side effects, though rare, can include unexplained muscle pain, severe tiredness, yellowing of the skin or eyes (signs of liver problems), dark urine, skin rashes or blisters (possible severe allergic reaction), or swelling in the face or throat. Muscle problems like rhabdomyolysis can occur, which may lead to kidney damage.

Precautions:

• Pregnancy and Breastfeeding: STATPURE EZ 10 Tablet is considered unsafe and contraindicated during pregnancy and is not recommended for breastfeeding women.
• Liver and Kidney Conditions: Caution is advised for individuals with mild to moderate liver impairment or kidney problems. Regular liver enzyme tests are recommended. It is contraindicated in active liver disease or severe kidney problems.
• Alcohol Consumption: Excessive alcohol intake should be avoided, as it can increase the risk of side effects and liver problems.
• Muscle Disorders: Individuals with a history of muscle disorders or those experiencing unexplained muscle pain or weakness should consult their doctor immediately, as the medication can worsen these conditions.
• Diabetes: Regular monitoring of blood sugar levels is advised, as an increase in HbA1c and fasting glucose levels can be observed.
• Drug Interactions: Inform your doctor about all medications, including over-the-counter drugs and supplements, to avoid potential interactions with anticoagulants (like warfarin), fibrates (like gemfibrozil), antacids, and certain hepatitis C medications.
• Allergies: Do not take if allergic to rosuvastatin, ezetimibe, or any other components of the tablet.
• Other Conditions: Use with caution in patients over 70 years old, those with thyroid disorders, severe lung disease, or a history of musculoskeletal disorders.

Storage: Store in a cool and dry place, away from direct sunlight and moisture. Keep the medicine out of sight and reach of children. The storage temperature should typically be below 30°C, or between 10ºC to 25ºC. Store in the original packaging to maintain quality.

Here are frequently asked questions about STATPURE EZ 10 TAB by MANKIND PHARMA LTD., a medication used to manage cholesterol levels.

What is STATPURE EZ 10 TAB used for?

STATPURE EZ 10 TAB is primarily used to treat high cholesterol levels (hyperlipidemia), including lowering "bad" cholesterol (LDL) and triglycerides, and increasing "good" cholesterol (HDL). It also helps reduce the risk of cardiovascular events such as heart attacks and strokes.

How does STATPURE EZ 10 TAB work?

This medicine is a combination of two active ingredients: Rosuvastatin and Ezetimibe. Rosuvastatin is a statin that blocks an enzyme in the liver (HMG-CoA reductase) responsible for cholesterol production, thereby reducing the amount of cholesterol the body makes. Ezetimibe works by blocking the absorption of cholesterol from the intestines. Together, they provide a more effective reduction in cholesterol levels.

What is the usual dosage for STATPURE EZ 10 TAB?

The recommended dose is typically one tablet daily, which can be taken with or without food. It is crucial to follow the dosage prescribed by your doctor and not to alter it without their consultation. Taking it at the same time each day helps maintain stable blood levels of the medication.

What are the possible side effects of STATPURE EZ 10 TAB?

Common side effects may include headache, muscle pain (myalgia), weakness or fatigue (asthenia), abdominal pain, nausea, and diarrhea. Some people might also experience joint pain, upper respiratory tract infection, or the common cold. More serious but rare side effects can include unexplained muscle pain, severe tiredness, yellowing of the skin or eyes (signs of liver problems), dark urine, skin rashes, or blisters. If you experience persistent or severe side effects, you should consult your doctor.

Is STATPURE EZ 10 TAB safe during pregnancy or breastfeeding?

No, STATPURE EZ 10 TAB is considered unsafe during pregnancy as it may harm the unborn baby. It is also not recommended for breastfeeding mothers, as the drug may pass into breast milk and potentially harm the baby. Women of childbearing age should use effective contraception while taking this medicine.

Can STATPURE EZ 10 TAB be taken with other medications?

STATPURE EZ 10 TAB can interact with certain medications. For example, it may increase the effects of anticoagulants like warfarin, potentially raising the risk of bleeding. Fibrates (e.g., gemfibrozil) can increase the risk of muscle problems when combined with rosuvastatin. Antacids containing aluminium and magnesium hydroxide may reduce the absorption of STATPURE EZ 10 TAB. Always inform your doctor about all other medicines, supplements, or herbal products you are taking to avoid potential interactions.

What precautions should be taken while using STATPURE EZ 10 TAB?

Caution is advised for individuals with liver or kidney problems, diabetes, or thyroid disorders. Regular monitoring of liver enzyme levels and blood sugar is recommended during treatment. Excessive alcohol consumption should be avoided. If you have a history of muscle disorders or experience unexplained muscle pain or weakness, especially with fever, notify your doctor immediately.

What happens if a dose of STATPURE EZ 10 TAB is missed?

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.

How should STATPURE EZ 10 TAB be stored?

STATPURE EZ 10 TAB should be stored in a cool, dry place, away from direct sunlight, moisture, and heat. It should be kept out of sight and reach of children and pets. Store it at room temperature, ideally below 30°C or between 10°C to 25°C.