Daparyl M 10/1000 Tab

DAPARYL M 10/1000 Tablet, manufactured by Intas Pharmaceuticals Ltd., is an oral antidiabetic medication used to manage Type 2 Diabetes Mellitus in adults.

Composition Each tablet contains Dapagliflozin 10 mg and Metformin 1000 mg. Dapagliflozin is a Sodium-Glucose Co-transporter 2 (SGLT2) inhibitor that reduces blood sugar by promoting glucose excretion through urine. Metformin, a biguanide, lowers glucose production in the liver, delays intestinal glucose absorption, and enhances the body's sensitivity to insulin.

Uses DAPARYL M 10/1000 Tablet is prescribed for:

• Treatment of Type 2 Diabetes Mellitus to control high blood sugar levels.
• Improving glycemic control, often in conjunction with diet and exercise.
• Reducing the risk of long-term diabetes complications such as kidney damage, blindness, and cardiovascular events.

Dosage and Administration Typically, one tablet is taken orally once daily, preferably with meals to minimize gastrointestinal side effects. Tablets should be swallowed whole with water and not crushed, chewed, or broken. Dosage is determined by a physician based on individual medical condition and response to treatment.

Side Effects Common side effects may include:

• Nausea, vomiting, diarrhea, abdominal pain, loss of appetite.
• Headache, dizziness.
• Frequent urination, urinary tract infections, and genital fungal infections. Serious but rare side effects include lactic acidosis, symptoms of which require immediate medical attention (e.g., severe tiredness, muscle cramps, difficulty breathing, low blood pressure).

Precautions DAPARYL M 10/1000 Tablet is not recommended for Type 1 diabetes, severe kidney or liver disease, diabetic ketoacidosis, or severe infections. Consult a doctor if pregnant or breastfeeding. Avoid excessive alcohol consumption, as it can increase the risk of lactic acidosis and hypoglycemia. Regular monitoring of blood sugar levels and kidney function is crucial during treatment.

Storage Store in a cool, dry place away from direct sunlight, ideally below 25°C or below 30°C. Keep out of sight and reach of children.

DAPARYL M 10/1000 TAB, manufactured by INTAS PHARMACEUTICALS LTD, is a medication commonly prescribed for the management of Type 2 Diabetes Mellitus. It combines two active ingredients, Dapagliflozin and Metformin, to help control blood sugar levels.

What is DAPARYL M 10/1000 TAB used for?

DAPARYL M 10/1000 TAB is used to treat Type 2 Diabetes Mellitus in adults. It helps improve blood sugar control when diet and exercise alone are not sufficient. This medication can also help reduce the risk of serious long-term complications associated with diabetes, such as kidney damage, blindness, and heart failure.

How does DAPARYL M 10/1000 TAB work?

This medicine contains two active ingredients: Dapagliflozin and Metformin. Dapagliflozin works by blocking a specific protein in the kidneys, causing excess sugar to be removed from the body through urine. Metformin works by reducing the amount of sugar produced by the liver, decreasing the absorption of sugar from the intestines, and increasing the body's sensitivity to insulin. Together, these actions help to lower blood sugar levels.

What is the usual dosage for DAPARYL M 10/1000 TAB?

The usual dosage is one tablet taken orally once daily. It is generally recommended to take it with meals to minimize stomach upset. Your doctor will determine the exact dose and duration of treatment based on your medical condition and response to the medication. It's crucial not to exceed the prescribed dose.

What are the possible side effects of DAPARYL M 10/1000 TAB?

Common side effects may include nausea, vomiting, diarrhea, abdominal pain, loss of appetite, headache, frequent urination, and genital fungal infections. Some individuals may also experience a mild skin rash or itchy skin. More serious, but less common, side effects can include dehydration and lactic acidosis. If any side effects persist or worsen, consult your doctor.

Is DAPARYL M 10/1000 TAB safe during pregnancy or breastfeeding?

DAPARYL M 10/1000 TAB is generally not recommended during pregnancy, especially in the second and third trimesters, as it may pose risks to the unborn baby. It is also considered unsafe during breastfeeding because its components may pass into breast milk and potentially affect the infant's kidney development. Always consult your doctor for safer alternative treatment options if you are pregnant, planning to conceive, or breastfeeding.

Can DAPARYL M 10/1000 TAB be taken with other medications?

This medicine can interact with certain other medications. It's important to inform your doctor about all medicines, supplements, or herbal products you are currently taking. Particular caution is advised when taking DAPARYL M 10/1000 TAB with diuretics (water pills), insulin or insulin secretagogues (which can increase the risk of low blood sugar), iodinated contrast agents used in X-rays, and certain medications like cimetidine, carbonic anhydrase inhibitors, ranolazine, vandetanib, dolutegravir, and lithium.

What precautions should be taken while taking DAPARYL M 10/1000 TAB?

Avoid consuming alcohol while taking this medication as it can increase the risk of a serious condition called lactic acidosis and may also cause low blood sugar. This medicine is not suitable for individuals with Type 1 diabetes, severe kidney or liver disease, diabetic ketoacidosis, or severe infections. Inform your doctor if you have a history of heart problems, low blood pressure, or recurrent urinary tract infections. Regular monitoring of kidney function is recommended.

What happens if a dose of DAPARYL M 10/1000 TAB is missed?

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to compensate for the missed one.

How should DAPARYL M 10/1000 TAB be stored?

DAPARYL M 10/1000 TAB should be stored in a cool, dry place, away from direct sunlight and moisture. The ideal storage temperature is below 25°C or 30°C. Keep the medicine in its original packaging and out of the reach and sight of children.