Susten 300mg Capsule

SUSTEN 300MG CAPSULE

SUSTEN 300MG CAPSULE, manufactured by SUN PHARMA LABORATORIES LTD., is a medication used primarily in women for various gynecological and reproductive health conditions.

• Name:

  • Brand Name: Susten 300 MG Capsule
  • Common Name: Progesterone (Natural Micronised)

• Composition:

  • Each capsule contains 300mg of Natural Micronised Progesterone.

• Uses: Susten 300 MG Capsule is prescribed for conditions related to hormonal imbalance, particularly involving progesterone deficiency. Its uses include:

  • Female Infertility: Supports the luteal phase in assisted reproductive technologies (ART) like IVF, aids in preparing the endometrium for implantation, and helps maintain early pregnancy.
  • Menstrual Disorders: Treats secondary amenorrhea (absence of periods), irregular menstruation, and abnormal uterine bleeding.
  • Hormone Replacement Therapy (HRT): Used in conjunction with estrogen to reduce menopausal symptoms and prevent endometrial hyperplasia (thickening of the uterine lining).
  • Pregnancy Support: Reduces the risk of threatened abortions and preterm delivery in women with a history of recurrent miscarriages or low progesterone levels.

• Dosage and Administration: The dosage and duration of Susten 300 MG Capsule should be strictly followed as directed by a doctor. It can be administered orally, vaginally, or rectally. When taken orally, it is often recommended to take it with food at the same time each day, usually at night, to enhance absorption and manage potential drowsiness. Do not crush or chew the capsule.

• Side Effects: Common side effects may include:

  • Headache, dizziness, and fatigue.
  • Nausea, vomiting, stomach pain, abdominal cramps, bloating, diarrhea, or constipation.
  • Breast pain, tenderness, or enlargement.
  • Abnormal or irregular vaginal bleeding/discharge, vaginal yeast infection.
  • Mood swings, depression, or insomnia.

  Serious side effects, though less common, warrant immediate medical attention and include signs of liver disease (yellow skin/eyes), severely high blood pressure, migraine-like headaches, sudden vision loss, blood clots, or breast lumps.

• Precautions:

  • Contraindications: Do not use if allergic to progesterone, or if you have a history of breast or uterine cancer, unexplained vaginal bleeding, severe liver impairment, or blood clotting disorders.
  • Medical History: Inform your doctor about any history of liver or kidney problems, heart conditions, diabetes, asthma, epilepsy, migraine, depression, or a family history of breast cancer or blood clots.
  • Pregnancy and Breastfeeding: It is often prescribed to support early pregnancy, but consult your doctor. Use during breastfeeding is generally not recommended without medical advice as progesterone is found in breast milk.
  • Driving: May cause dizziness or drowsiness; exercise caution when driving or operating machinery.
  • Drug Interactions: Inform your doctor about all other medications you are taking, including herbal supplements, as some can interact with progesterone (e.g., rifampicin, carbamazepine, ketoconazole, insulin, warfarin).

• Storage: Store in a cool, dry place, protected from moisture and direct sunlight, at a temperature not exceeding 30°C (86°F). Keep out of sight and reach of children and pets. Do not freeze.

What is Susten 300mg Capsule used for?

Susten 300mg Capsule is primarily used for hormone replacement therapy (HRT) to manage symptoms of menopause and prevent endometrial hyperplasia (thickening of the uterine lining) when taken with estrogen. It is also prescribed to treat menstrual disorders, such as secondary amenorrhea (absence of periods) and irregular menstruation. Additionally, it supports early stages of pregnancy, helps prevent threatened abortions and preterm delivery, and addresses female infertility or luteal phase deficiency.

How does Susten 300mg Capsule work?

Susten 300mg Capsule contains natural micronized progesterone, a female hormone. It works by supplementing the body with sufficient levels of progesterone. This helps induce secretory changes in the endometrium (uterine lining), making it suitable for embryo implantation and maintaining the uterine lining during pregnancy. It also helps relax the uterus, block follicular maturation and ovulation, and regulate overall hormonal balance in the body.

What is the usual dosage for Susten 300mg Capsule?

The dosage and duration of Susten 300mg Capsule are determined by your doctor based on your specific condition. It is often recommended to take it at the same time every day. While it can be taken with or without food, taking it with food may help reduce nausea. For conditions like amenorrhea or dysfunctional uterine bleeding, an adult dose might be 400 mg daily for 10 days. For preventing endometrial hyperplasia, a common regimen is 200 mg orally at night for 12 days sequentially per 28-day cycle.

What are the possible side effects of Susten 300mg Capsule?

Common side effects include headache, mood swings, vaginal discharge or irritation, breast pain and tenderness, muscle or joint pain, constipation, nausea, vomiting, stomach cramps, bloating, dizziness, fatigue, sleepiness, irregular vaginal bleeding or spotting, hair loss, and edema (swelling). More serious, though less common, side effects can include breast lumps, blurred or loss of vision, unexpected significant vaginal bleeding, swelling of the face, lips, eyelids, tongue, hands and feet, chest pain, difficulty in passing urine, fever and chills, convulsions, and blood clots.

Is Susten 300mg Capsule safe during pregnancy or breastfeeding?

During Pregnancy: Susten 300mg Capsule is generally considered safe to use during pregnancy when prescribed by a doctor, especially for supporting pregnancy and preventing premature labor or miscarriage.

During Breastfeeding: It is generally considered safe to use during breastfeeding. While progesterone, the active ingredient, passes into breast milk, studies suggest it does not do so in significant amounts that would be harmful to the baby.

Can Susten 300mg Capsule be taken with other medications?

Susten 300mg Capsule can interact with several medications. These include antiepileptics (e.g., carbamazepine, phenytoin, phenobarbital), certain antibiotics (e.g., rifampicin, tetracyclines), anti-HIV drugs (e.g., nelfinavir), St. John's Wort, bromocriptine, cyclosporine, antifungal agents (e.g., ketoconazole), and oral anticoagulants (blood thinners). It may also interact with insulin and, in some cases, show severe interactions with drugs like venetoclax and bosentan. Always inform your doctor about all other medications, supplements, and herbal products you are taking to avoid potential interactions.

What precautions should be taken while using Susten 300mg Capsule?

Before taking Susten 300mg Capsule, inform your doctor about your medical history, especially if you have or have had breast cancer, undiagnosed abnormal vaginal bleeding, liver disease, a history of blood clots or thromboembolic disorders, heart problems, depression, epilepsy or seizures, migraines, asthma, diabetes, high blood pressure, or high cholesterol. This medicine can cause dizziness or fatigue, so exercise caution when driving or operating machinery. Do not use this medication if you are allergic to progesterone or any other components of the capsule.

What happens if a dose of Susten 300mg Capsule is missed?

If you miss a dose of Susten 300mg Capsule, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one, as this may lead to adverse effects.

How should Susten 300mg Capsule be stored?

Susten 300mg Capsule should be stored below 30°C (room temperature). Keep it in a cool, dry place, away from direct heat and sunlight, and in its original packaging. Ensure it is kept out of sight and reach of children and pets. Do not use the medication after its expiration date.