Glytrin Met 1000

GLYTRIN MET 1000

GLYTRIN MET 1000 is a medication manufactured by Medley Pharmaceuticals Ltd.. It is an antidiabetic agent prescribed for the management of type 2 diabetes mellitus.

• Composition GLYTRIN MET 1000 contains two active ingredients:

  • Metformin (1000 mg)
  • Teneligliptin (20 mg)

• Uses GLYTRIN MET 1000 is used to treat type 2 diabetes mellitus in adults. It helps improve glycemic control by decreasing glucose production in the liver, reducing intestinal glucose uptake, and increasing insulin levels in the body. This medication is typically prescribed when diet and exercise alone are insufficient, or when patients do not respond adequately to Metformin alone. Effective blood sugar control helps prevent serious diabetes-related complications such as kidney damage, blindness, heart attack, and stroke.

• Dosage and Administration GLYTRIN MET 1000 should be taken orally with meals, as directed by a healthcare professional. Tablets should be swallowed whole with water and should not be crushed, chewed, or broken. The exact dosage and frequency (often once or twice daily) will be determined by the doctor based on the individual's condition, blood sugar levels, and response to treatment.

• Side Effects

  • Common Side Effects: Nausea, vomiting, diarrhoea, headache, stomach ache/abdominal discomfort, respiratory infection, weight gain, sweating, nasal congestion, sore throat, and hypoglycemia (low blood sugar). These side effects are usually mild and may resolve over time.
  • Serious Side Effects: A rare but serious condition called lactic acidosis (symptoms include abdominal pain, muscle cramps, vomiting, severe fatigue, difficulty breathing, deep or rapid breathing). Long-term use may also lead to Vitamin B12 deficiency.

• Precautions Inform your doctor about any pre-existing medical conditions, ongoing medications, pregnancy, or breastfeeding status before taking GLYTRIN MET 1000.

  • Contraindications: Should not be used if allergic to its components, or in cases of severe ketosis, type 1 diabetes, diabetic coma, severe renal impairment, severe kidney disease, liver impairment, congestive heart failure, lactic acidosis, or diabetic ketoacidosis.
  • Pregnancy and Breastfeeding: Not recommended for use during pregnancy or while breastfeeding.
  • Alcohol Consumption: Excessive alcohol intake may increase the risk of lactic acidosis.
  • Driving and Operating Machinery: Caution is advised as the medication may cause vision problems or dizziness.
  • Monitoring: Regular monitoring of blood sugar levels and kidney function is advisable during treatment.
  • Diet and Exercise: This medication works best when combined with a balanced diet and regular exercise.

• Storage Store GLYTRIN MET 1000 in a cool, dry place, protected from direct sunlight, moisture, and heat, typically between 10ºC to 30ºC. Keep the medicine out of the sight and reach of children. Do not use expired or damaged medicines.

Here are frequently asked questions about GLYTRIN MET 1000 by MEDLEY, along with concise answers:

What is GLYTRIN MET 1000 used for?

GLYTRIN MET 1000 is primarily used to treat type 2 diabetes mellitus in adults. It helps manage high blood sugar levels, especially when diet and exercise, or Metformin alone, are not sufficient. This helps prevent serious diabetes complications like kidney damage, blindness, heart attacks, and strokes.

How does GLYTRIN MET 1000 work?

This medicine contains two active ingredients: Metformin and Teneligliptin. Metformin works by reducing the liver's glucose production, decreasing glucose absorption from the intestines, and enhancing the body's response to insulin. Teneligliptin, a DPP-4 inhibitor, increases insulin levels and reduces glucagon levels in the body, particularly after meals, leading to lower blood sugar.

What is the usual dosage of GLYTRIN MET 1000?

GLYTRIN MET 1000 should be taken exactly as prescribed by your doctor, typically once daily with meals. It is important to swallow the tablet whole with water and not to crush, chew, or break it. Your doctor will determine the appropriate dosage based on your condition, blood sugar levels, and other medications you may be taking.

What are the possible side effects of GLYTRIN MET 1000?

Common side effects may include nausea, vomiting, diarrhea, headache, stomach ache, respiratory infection, weight gain, and sweating. A rare but serious side effect is lactic acidosis, which is a buildup of lactic acid in the blood, and symptoms can include abdominal pain, muscle cramps, vomiting, severe fatigue, or difficulty breathing. Long-term use of Metformin may also lead to Vitamin B12 deficiency.

Is GLYTRIN MET 1000 safe during pregnancy or breastfeeding?

GLYTRIN MET 1000 is generally not recommended for use during pregnancy or while breastfeeding. It is crucial to inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding, as alternative treatment options may be necessary.

Can GLYTRIN MET 1000 be taken with other medications?

It is essential to inform your doctor about all other medications you are currently taking, including over-the-counter drugs and herbal supplements. Certain medicines, like cationic drugs such as amiloride, cimetidine, and ranitidine, can increase Metformin levels in the body, potentially increasing the risk of lactic acidosis.

What precautions should be taken while using GLYTRIN MET 1000?

Do not take GLYTRIN MET 1000 if you have severe kidney or liver disease, severe ketosis, type 1 diabetes, or a history of diabetic coma. Caution is advised if you have heart problems, severe infections, or are undergoing surgery. Avoid excessive alcohol consumption, as it can increase the risk of lactic acidosis. Your doctor may monitor your kidney function and Vitamin B12 levels regularly.

What happens if a dose of GLYTRIN MET 1000 is missed?

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed one.

How should GLYTRIN MET 1000 be stored?

Store GLYTRIN MET 1000 in a cool and dry place, protected from direct sunlight, moisture, and heat. It should typically be stored at room temperature, between 10ºC to 30ºC. Always keep the medicine out of the sight and reach of children.