Xmet Sr 500 Mg Tablet (15 Tab)

XMET SR 500 MG TABLET (15 TAB) by GLENMARK PHARMACEUTICALS LTD.

Name:

• Brand Name: XMET SR 500 MG TABLET
• Common Name: Metformin (Sustained Release)

Composition:

• Active Ingredient: Metformin Hydrochloride 500mg

Uses: XMET SR 500 MG TABLET is primarily used for the management of type 2 diabetes mellitus when diet and exercise alone are insufficient to control blood glucose levels. It is also prescribed for Polycystic Ovary Syndrome (PCOS) in women, helping to improve insulin sensitivity and regulate hormonal imbalances. Additionally, it may aid in weight management and reduce the risk of heart disease in diabetic patients.

Dosage and Administration: This medication should be taken exactly as prescribed by a healthcare professional. The usual starting dose is typically one tablet once or twice daily, taken with meals to minimize gastrointestinal side effects. The 'SR' formulation signifies sustained release, meaning the medication is released gradually over an extended period. Tablets should be swallowed whole and not crushed or chewed.

Side Effects:

• Common Side Effects: Nausea, vomiting, diarrhea, stomach pain, altered taste sensations (metallic taste), loss of appetite, weakness, indigestion, and headache. Long-term use may lead to Vitamin B12 deficiency.
• Serious Side Effects: A rare but serious side effect is lactic acidosis, symptoms of which include weakness, fatigue, muscle pain, trouble breathing, and severe stomach pain with nausea and vomiting. Immediate medical attention is required if these symptoms occur.

Precautions: Inform your doctor about any existing kidney, liver, or heart problems, as well as severe infections or dehydration, as these conditions may contraindicate the use of XMET SR 500 MG TABLET. Avoid excessive alcohol consumption while on this medication, as it can increase the risk of hypoglycemia and lactic acidosis. Regular monitoring of blood sugar levels and kidney function is crucial during treatment. Interactions can occur with other medications, including certain pain relievers, diuretics, and other anti-diabetic drugs, potentially affecting blood sugar levels.

Storage: Store XMET SR 500 MG TABLET at room temperature, ideally below 30°C, away from heat, direct light, and moisture. Keep it out of the reach of children and pets.

XMET SR 500 MG Tablet is a medication containing Metformin Hydrochloride, primarily used for managing blood sugar levels in individuals with Type 2 Diabetes Mellitus. It is a sustained-release (SR) formulation, designed to provide a gradual release of the medication.

What is XMET SR 500 MG Tablet used for?

XMET SR 500 MG Tablet is primarily used to manage blood sugar levels in adults with Type 2 Diabetes Mellitus when diet and exercise alone are insufficient. It is also used to manage Polycystic Ovary Syndrome (PCOS) in women, helping to improve insulin sensitivity and regulate hormonal imbalances. Additionally, it may aid in weight management and prediabetes management, and potentially reduce the risk of heart disease in diabetic patients.

How does XMET SR 500 MG Tablet work?

XMET SR 500 MG Tablet, with its active ingredient Metformin, works through several mechanisms to control blood sugar. It primarily reduces the amount of glucose produced by the liver (hepatic gluconeogenesis) and decreases the absorption of glucose from the intestines after meals. It also improves the body's sensitivity to insulin, a hormone that helps glucose enter cells for energy, thereby lowering blood sugar levels. The sustained-release (SR) formulation ensures a more consistent drug level in the bloodstream, contributing to better glycemic control.

What is the usual dosage of XMET SR 500 MG Tablet?

The usual starting dose for adults is typically 500 mg once daily, taken with the evening meal to minimize gastrointestinal side effects. Your doctor may gradually increase the dosage in increments, usually not exceeding a maximum daily dose of 2000-2500 mg. It is crucial to swallow the tablets whole and not to crush or chew them, as this can disrupt the sustained-release mechanism. Always follow your doctor's specific instructions regarding dosage and administration.

What are the possible side effects of XMET SR 500 MG Tablet?

Common side effects may include nausea, vomiting, diarrhea, abdominal pain, loss of appetite, and a metallic taste in the mouth. These are usually mild and temporary. In rare cases, a serious side effect called lactic acidosis can occur. Symptoms of lactic acidosis include weakness, fatigue, muscle pain, trouble breathing, stomach pain with nausea and vomiting, dizziness, or lightheadedness, and require immediate medical attention. Long-term use may also lead to Vitamin B12 deficiency.

Is XMET SR 500 MG Tablet safe during pregnancy or breastfeeding?

XMET SR 500 MG Tablet should be used with caution during pregnancy, and insulin is generally preferred for managing pregnancy-related diabetes. It is known to pass into breast milk in small amounts, so it is advisable to consult your doctor before using it while breastfeeding.

Can XMET SR 500 MG Tablet be taken with other medications?

Yes, XMET SR 500 MG Tablet can interact with other medications. Combining it with other anti-diabetic medications like insulin or sulfonylureas can increase the risk of low blood sugar (hypoglycemia). Certain medications such as diuretics (e.g., furosemide), corticosteroids (e.g., prednisolone), and some non-steroidal anti-inflammatory drugs (NSAIDs) like ibuprofen, can also interact with Metformin, potentially affecting its effectiveness or increasing the risk of lactic acidosis. Always inform your doctor about all other medications, including over-the-counter drugs and herbal supplements, you are taking.

What precautions should be taken while using XMET SR 500 MG Tablet?

It is not recommended for patients with severe kidney or liver problems, as it can accumulate in the body and increase the risk of lactic acidosis. Excessive alcohol consumption should be avoided as it can increase the risk of lactic acidosis and hypoglycemia. Regular monitoring of blood sugar levels and kidney function is crucial during treatment. Do not crush or chew the tablet. Inform your doctor about any pre-existing medical conditions, especially heart problems or allergies.

What happens if a dose of XMET SR 500 MG Tablet is missed?

If you miss a dose of XMET SR 500 MG Tablet, take it as soon as you remember, preferably with food. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one.

How should XMET SR 500 MG Tablet be stored?

XMET SR 500 MG Tablet should be stored at room temperature, away from heat, light, and moisture. Keep it out of the reach of children and pets. Store it below 25°C or below 30°C in a cool and dry place away from sunlight.