Nadibact 1% Gel 10gm

NADIBACT 1% GEL 10GM by Cipla Ltd.

Name

• Common Name: Nadibact Gel
• Brand Name: NADIBACT 1% GEL 10GM (manufactured by Cipla Ltd.)

Composition

• Active Ingredients: Nadifloxacin 1% w/w in a gel base.

Uses

NADIBACT 1% GEL is a topical antibiotic primarily prescribed for the treatment of various bacterial skin infections. It is effective against:

• Acne vulgaris (mild to moderate)
• Superficial bacterial infections of the skin
• Boils
• Impetigo
• Infected hair follicles (folliculitis)
• Infections in small cuts or wounds on the skin

Dosage and Administration

• NADIBACT 1% GEL is for external (dermal) application only.
• Clean and dry the affected area before application.
• Apply a thin layer of the gel to the lesions twice daily, or as directed by your doctor.
• In the case of acne, it should be applied after washing the face.
• Wash hands thoroughly before and after applying the medicine, unless hands are the area being treated.
• Do not use it more often or for longer than advised by your doctor; treatment duration should be the shortest feasible to minimize resistance.

Side Effects

Common Side Effects (may occur at the site of application):

• Burning sensation
• Irritation
• Itching
• Redness (erythema)
• Dryness of the skin
• Desquamation (peeling of skin)

Infrequent/Less Common Side Effects:

• Flushes
• Papules
• Feeling of facial warmth
• Increased sweating
• Contact dermatitis

Serious allergic reactions are rare, but medical attention should be sought if symptoms like severe rash, swelling (face, tongue, throat), or difficulty breathing occur.

Precautions

• External Use Only: This gel is strictly for topical application. Avoid contact with eyes, mouth, nose, mucous membranes, or broken skin. If accidental contact occurs, rinse immediately and thoroughly with plenty of water and consult a doctor if irritation persists.
• Hypersensitivity: Do not use if you have a history of hypersensitivity reactions to nadifloxacin or any other components of the gel.
• Bacterial Resistance: Susceptibility testing should ideally be performed before use. To minimize the development of resistant microorganisms, the treatment duration should be the shortest feasible.
• Occlusive Dressings: Avoid covering the treated area with airtight dressings (e.g., bandages) unless specifically instructed by a doctor, as this may increase systemic absorption and the risk of side effects.
• Pregnancy: The safety of Nadibact Gel during pregnancy has not been established. Animal studies have shown harmful effects on the developing baby. Consult your doctor to weigh the benefits against potential risks.
• Breastfeeding: Nadibact Gel is probably unsafe to use during breastfeeding as limited human data suggests it may pass into breast milk. If prescribed, thoroughly wash the treated area, especially around the breast, before breastfeeding to prevent ingestion by the baby.
• Pediatric Use: Not recommended for children under 12 or 14 years of age due to insufficient safety and efficacy data.
• Drug Interactions: Inform your doctor about all other medications you are taking to prevent potential interactions.
• Sunlight Exposure: Avoid excessive exposure to sunlight as it may increase the risk of phototoxicity or photosensitivity.
• Lack of Improvement: Consult your doctor if your skin condition does not improve after seven days of treatment or if symptoms worsen.

Storage

• Store in a cool, dry place.
• Protect from direct sunlight.
• Keep at a temperature no higher than 25°C.
• Do not freeze.
• Keep out of the sight and reach of children and pets.

Here are the most frequently asked questions about NADIBACT 1% GEL 10GM, along with their concise answers.

What is Nadibact 1% Gel used for?

Nadibact 1% Gel is an antibiotic used to treat bacterial skin infections, including conditions such as acne vulgaris, boils, impetigo, and infected hair follicles. It can also be applied to infections in small cuts or wounds on the skin.

How does Nadibact 1% Gel work?

Nadibact 1% Gel contains nadifloxacin, a fluoroquinolone antibiotic. It works by inhibiting bacterial DNA synthesis and multiplication, which prevents the bacterial cells from dividing and repairing themselves, thereby killing the infection-causing bacteria. It also possesses anti-inflammatory properties.

What is the usual dosage for Nadibact 1% Gel?

Nadibact 1% Gel is for external use only. It should be applied to the affected areas twice daily, or as directed by your doctor. Before application, ensure the affected skin area is clean and dry. Always wash your hands thoroughly before and after applying this medicine.

What are the possible side effects of Nadibact 1% Gel?

Common side effects at the application site may include a burning sensation, irritation, itching, redness, and dryness. Less frequently, flushes, papules, increased sweating, and contact dermatitis may occur. Consult your doctor if these side effects persist or worsen.

Is Nadibact 1% Gel safe during pregnancy or breastfeeding?

• Pregnancy: Nadibact Gel may be unsafe to use during pregnancy. While human studies are limited, animal studies have indicated harmful effects on the developing baby. It is important to consult your doctor before using this medicine if you are pregnant or planning a pregnancy.
• Breastfeeding: Nadibact Gel is likely unsafe during breastfeeding. Limited human data suggests the drug may pass into breast milk and could potentially harm the baby. If prescribed while breastfeeding, ensure to wash the breast area thoroughly before feeding to prevent the baby from ingesting the gel.

Can Nadibact 1% Gel be taken with other medications?

As Nadibact 1% Gel is applied topically, it is less likely to interact with other systemic medications. However, you should always inform your doctor about all other medicines you are taking, including prescribed, non-prescribed, herbal remedies, dietary supplements, and other topical treatments, to avoid any potential interactions.

What precautions should be taken while using Nadibact 1% Gel?

Nadibact 1% Gel is strictly for external use. Avoid contact with your eyes, mouth, nose, and broken skin. If accidental contact occurs, rinse immediately with plenty of water. Do not use this gel if you are allergic to nadifloxacin or any of its ingredients. Avoid covering the treated area with airtight dressings like bandages unless specifically instructed by your doctor, as this might increase the risk of side effects. If your skin condition does not improve after seven days (or four weeks for acne), inform your doctor. Treatment should generally be continued for at least two days after the infection has cleared. The gel is not recommended for children under 14 years of age due to insufficient safety and efficacy data. Additionally, avoid prolonged exposure to sunlight as it may increase photosensitivity.

What happens if a dose of Nadibact 1% Gel is missed?

If you miss an application of Nadibact 1% Gel, apply it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular application schedule. Do not apply a double dose to compensate for the missed one.

How should Nadibact 1% Gel be stored?

Store Nadibact 1% Gel in a cool, dry place, protected from direct sunlight, and at a temperature below 25°C. It should not be frozen. Keep this medicine out of the sight and reach of children, and do not use it after its expiry date.