Budez Cr Capsule (10 Cap)

BUDEZ CR CAPSULE

Budez CR Capsule is a controlled-release medication manufactured by Sun Pharma Laboratories Ltd., primarily used for its anti-inflammatory properties.

• Composition: Each capsule contains 3 mg of Budesonide as its active ingredient. Budesonide is a synthetic glucocorticosteroid that works by reducing inflammation in the digestive tract. The "CR" in Budez CR denotes its controlled-release formulation, which allows the medication to be gradually released and act locally in the intestines, thereby maximizing effectiveness in affected areas while minimizing systemic absorption.

• Uses: Budez CR Capsule is primarily prescribed for the treatment of inflammatory bowel diseases (IBD). This includes:

  • Crohn's Disease: Used for mild to moderate cases, particularly when affecting the ileum and/or ascending colon, to reduce inflammation and manage symptoms.
  • Ulcerative Colitis: Treats active, mild to moderate ulcerative colitis by reducing inflammation in the colon and rectum.
  • Microscopic Colitis: Helps in alleviating symptoms associated with this condition. The medication works by suppressing the immune system's inflammatory response in the gut, thereby reducing symptoms like abdominal pain and diarrhea.

• Dosage and Administration: Typically, one Budez CR 3mg capsule is taken once daily in the morning. Capsules should be swallowed whole with a glass of water and not crushed, chewed, or broken. It can be taken before or with food, but following the doctor's specific instructions is crucial. The duration of treatment is usually decided by the doctor, often for up to 8 weeks, and the dose should be gradually reduced before discontinuation.

• Side Effects: Common side effects may include headache, nausea, abdominal pain, bloating, gas, acne, and mood changes. Other reported side effects include dizziness, vomiting, fatigue, stuffy nose, sneezing, sore throat, and back or joint pain. Serious side effects, though less common, can include an increased risk of infection, muscle weakness, elevated blood sugar levels, signs of Cushing syndrome (e.g., weight gain, round face, acne), blurred vision, severe depression, or suicidal thoughts.

• Precautions:

  • Consult a doctor if pregnant or breastfeeding, as budesonide may pass into breast milk.
  • Caution is advised in patients with liver disease, kidney problems, diabetes (as it can affect blood sugar), hypertension, osteoporosis, glaucoma, cataracts, tuberculosis, or a weakened immune system.
  • Avoid or limit alcohol consumption during treatment.
  • May interact with certain medications, including antifungals (e.g., ketoconazole), antibiotics (e.g., erythromycin), oral contraceptives containing estrogen, rifampin, and some antihypertensives.
  • Budez CR Capsule is generally not recommended for children under 12 years of age unless specifically prescribed by a doctor.

• Storage: Budez CR capsules should be stored at room temperature, typically below 30°C or between 20-25°C, protected from moisture, heat, and direct sunlight. Keep the medicine out of the sight and reach of children and pets.

Here are frequently asked questions about BUDEZ CR CAPSULE (10 CAP) by SUN PHARMA LABORATORIES LTD., along with concise answers:

What is Budez CR Capsule used for?

Budez CR Capsule contains Budesonide, a corticosteroid primarily used to manage inflammatory bowel diseases (IBD) such as mild to moderate Crohn's disease affecting the ileum and/or ascending colon, ulcerative colitis, and microscopic colitis. It helps to reduce inflammation in the digestive tract.

How does Budez CR Capsule work?

Budez CR Capsule works by suppressing the body's immune system and reducing the inflammatory response in the digestive tract. The active ingredient, budesonide, acts locally in the intestines to block the production of certain chemical mediators that cause inflammation. Its controlled-release formulation ensures targeted action, which helps to minimize systemic side effects.

What is the usual dosage for Budez CR Capsule?

The dosage of Budez CR Capsule is determined by your doctor based on your specific medical condition. For conditions like mild to moderate active Crohn's disease or ulcerative colitis, a common dosage is 9 milligrams (mg) once a day, typically in the morning, for up to 8 weeks. It should be swallowed whole with a glass of water, usually before breakfast, and not crushed, chewed, or broken. Do not change your dose or stop taking the medicine without consulting your doctor, as the dosage may need to be gradually reduced.

What are the possible side effects of Budez CR Capsule?

Common side effects can include headache, nausea, stomach pain, bloating, dizziness, muscle pain, fatigue, and depression. More serious side effects, though less common, can include signs of Cushing's syndrome (e.g., weight gain, round face, increased bruising), high blood sugar, increased blood pressure, increased risk of infections (fever, chills, persistent sore throat), and eye problems like glaucoma or cataracts. You should contact your doctor immediately if you experience severe side effects or signs of infection.

Is Budez CR Capsule safe during pregnancy or breastfeeding?

During pregnancy: Budez CR Capsule should be used in pregnant women only if clearly prescribed by a physician, as the potential benefits must outweigh any potential risks to the unborn baby. During breastfeeding: It is not known if the medicine passes into breast milk and could affect a breastfeeding infant. Consult your doctor before using Budez CR Capsule if you are breastfeeding.

Can Budez CR Capsule be taken with other medications?

It is important to inform your doctor about all other medicines, including over-the-counter drugs, vitamins, and herbal supplements you are taking. Budez CR Capsule should generally be avoided with certain medications, such as antifungal medicines (e.g., ketoconazole, itraconazole) and some antiviral medicines (e.g., ritonavir, nelfinavir). It should also be used with caution with other corticosteroids, certain antibiotics, and oral contraceptives containing estrogen. Antacids or cholestyramine should be taken at least 2 hours before or after Budez CR Capsule.

What precautions should be taken while using Budez CR Capsule?

Avoid consuming grapefruit juice while taking Budez CR Capsule, as it can increase the risk of side effects. Inform your doctor if you have stomach ulcers, any infections, or are scheduled for vaccinations, as the medicine can suppress your immune system, making you more susceptible to infections. Use with caution if you have diabetes, high blood pressure, osteoporosis, liver or kidney problems, glaucoma, or cataracts. Do not drive or operate machinery if you experience dizziness or weakness. This medicine is generally not recommended for children and adolescents under 18 years unless specifically advised by a doctor.

What happens if a dose of Budez CR Capsule is missed?

If you miss a dose of Budez CR Capsule, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed one.

How should Budez CR Capsule be stored?

Budez CR Capsule should be stored at room temperature, ideally between 20-25°C (68-77°F), protected from moisture, heat, and direct light. Keep the capsules in their original packaging and out of the sight and reach of children and pets. It should not be frozen.