Oxra S 5/100mg Tab

OXRA S 5/100MG TAB

OXRA S 5/100MG TAB is a combination medication manufactured by SUN PHARMA MAIN DIVISION (V.V.) used to manage Type 2 Diabetes Mellitus.

• Name

  • Brand Name: OXRA S 5/100MG TAB
  • Common Name: Dapagliflozin and Sitagliptin Tablets

• Composition Each tablet contains:

  • Dapagliflozin: 5 mg
  • Sitagliptin: 100 mg

• Uses OXRA S 5/100MG TAB is prescribed for adults with Type 2 Diabetes Mellitus, particularly when blood sugar levels are not adequately controlled by metformin alone, or as an add-on to other diabetes medicines. It works by improving blood sugar control through a dual mechanism. This medication helps lower elevated blood glucose, improve insulin sensitivity, reduce glucose production in the liver, and increase glucose excretion through urine. Controlling high blood sugar helps prevent serious complications of diabetes such as kidney damage, blindness, nerve problems, limb loss, and may lessen the risk of a heart attack or stroke. It is also used to treat chronic kidney disease in adults with reduced kidney function.

• Dosage and Administration This medication is taken orally, typically once daily, with or without food, as directed by a doctor. Tablets should be swallowed whole and not chewed, crushed, or broken. It is advisable to take the medication at the same time each day to maintain consistent medicine levels. The dosage is determined by the doctor based on the patient's medical condition and response to treatment. Do not stop taking this medicine abruptly without consulting a doctor, as it may lead to increased blood sugar levels and a higher risk of complications.

• Side Effects

  • Common Side Effects: Urinary tract infection (UTI), headache, nasopharyngitis (cold-like symptoms), diarrhea, back pain, frequent urination, dizziness or light-headedness, genital fungal infections (in both females and males), nausea, vomiting, flatulence, and constipation.
  • Serious Side Effects: Hypoglycaemia (low blood sugar) especially when used with other anti-diabetic medicines or alcohol, pancreatitis (inflammation of the pancreas presenting as severe stomach pain), serious allergic reactions (rash, hives, swelling of the face/lips/tongue/throat, difficulty breathing), dehydration, low blood pressure, worsening kidney function, and in rare cases, necrotizing fasciitis of the perineum (Fournier's gangrene).

• Precautions OXRA S 5/100MG TAB is not recommended for individuals with Type 1 Diabetes Mellitus or severe kidney/liver disease, or those on dialysis. Caution is advised for patients with a history of pancreatitis, heart disease, gallstones, alcohol dependence, or very high levels of triglycerides. Pregnant or breastfeeding women should consult their doctor, as its use is generally not recommended unless clearly necessary. Avoid excessive alcohol consumption as it can increase the risk of side effects like hypoglycemia. The medicine may cause dizziness, so caution is advised when driving or operating machinery. Patients should maintain good hygiene to prevent genital infections. Inform the doctor about all other medications, supplements, or herbal products being taken to avoid potential drug interactions, especially with insulin, insulin secretagogues, diuretics, rifampin, antifungals, antivirals, immunosuppressants, and cardiac glycosides. Regular monitoring of blood sugar levels is crucial.

• Storage Store OXRA S 5/100MG TAB in a cool, dry place, away from direct sunlight and moisture. Keep it out of the sight and reach of children. Store below 30°C.

Here are frequently asked questions about OXRA S 5/100MG TAB, a medication containing Dapagliflozin and Sitagliptin.

What is OXRA S 5/100MG TAB used for?

OXRA S 5/100MG TAB is used to treat type 2 diabetes mellitus in adults. It helps control high blood sugar levels, especially when diet, exercise, and other medications alone are not sufficient. It can also help reduce the risk of diabetes-related complications like kidney damage, nerve issues, eyesight loss, and cardiovascular events, and may be used in adults with reduced kidney function to treat chronic kidney disease.

How does OXRA S 5/100MG TAB work?

OXRA S 5/100MG TAB is a combination of two antidiabetic medications: Dapagliflozin and Sitagliptin. Dapagliflozin works by increasing the removal of sugar from the body through the kidneys into the urine. Sitagliptin works by increasing insulin levels and decreasing glucagon levels (a hormone that raises blood glucose), thereby reducing the amount of glucose the liver produces. Together, they improve insulin sensitivity and help regulate blood sugar levels.

What is the usual dosage for OXRA S 5/100MG TAB?

The dosage of OXRA S 5/100MG TAB is determined by your doctor and is based on your medical condition and response to treatment. It is usually taken by mouth once daily, preferably at the same time each day, with or without food. Do not stop taking it without consulting your doctor, as this can lead to increased blood sugar levels and complications.

What are the possible side effects of OXRA S 5/100MG TAB?

Common side effects may include urinary tract infections (UTIs), genital fungal infections, headache, diarrhea, nasal congestion, sore throat, upper respiratory tract infections, and back pain. It may also cause dehydration or more frequent urination, so staying well-hydrated is important. Some individuals might experience dizziness or light-headedness.

Is OXRA S 5/100MG TAB safe during pregnancy or breastfeeding?

Limited information is available on the use of OXRA S 5/100MG TAB during pregnancy and breastfeeding. It should be used in pregnant women only if considered clearly necessary, and with caution in breastfeeding women, after consulting a doctor.

Can OXRA S 5/100MG TAB be taken with other medications?

OXRA S 5/100MG TAB can interact with several medications. Inform your doctor about all medicines, supplements, or herbal products you are currently taking. Particular care is needed if you are taking other anti-diabetic medicines (like insulin or sulfonylureas), diuretics (water pills), anti-fungal medications (e.g., ketoconazole), anti-viral agents (e.g., ritonavir), certain antibiotics (e.g., clarithromycin), immunosuppressants (e.g., ciclosporin), or cardiac glycosides (e.g., digoxin). Combining it with insulin or sulfonylureas may increase the risk of very low blood sugar levels.

What precautions should be taken while using OXRA S 5/100MG TAB?

Do not take OXRA S 5/100MG TAB if you have type 1 diabetes mellitus or severe kidney or liver disease. Inform your doctor if you have a history of pancreatitis, heart failure, low blood pressure, urinary tract infections, or if you are dehydrated. Avoid excessive alcohol consumption, as it can increase the risk of side effects and diabetic ketoacidosis. Regular monitoring of blood sugar and kidney function is crucial.

What happens if a dose of OXRA S 5/100MG TAB is missed?

If you miss a dose of OXRA S 5/100MG TAB, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed one.

How should OXRA S 5/100MG TAB be stored?

Store OXRA S 5/100MG TAB in a cool and dry place, away from direct sunlight and moisture. Keep it out of the sight and reach of children. Do not use the medicine past its expiry date.