Coversyl Am 4/10 Mg Tablet (10 Tab)

COVERSYL AM 4/10 MG TABLET

Name:

• Common Name: COVERSYL AM 4/10 MG TABLET
• Brand Name: COVERSYL AM
• Manufacturer: SERDIA PHARMACEUTICALS (INDIA) PVT. LTD.

Composition: COVERSYL AM 4/10 MG TABLET contains a combination of two active ingredients:

• Amlodipine (10 mg): A calcium channel blocker.
• Perindopril (4 mg) (as Perindopril erbumine or Perindopril arginine): An Angiotensin-Converting Enzyme (ACE) inhibitor.

Uses: This medication is primarily prescribed for the treatment of:

• Hypertension (high blood pressure), especially when a single medication is not effective.
• Stable coronary artery disease. It helps relax blood vessels, improve blood flow, and reduce strain on the heart, thereby lowering the risk of future heart attack and stroke. It can also be used to treat angina and prevent heart failure.

Dosage and Administration:

• Typically, one tablet is taken once daily.
• It should be taken on an empty stomach, preferably before a meal.
• Take the tablet at the same time each day for consistency.
• Swallow the tablet whole; do not chew, crush, or break it.
• Do not stop taking this medicine without consulting your doctor, as abrupt discontinuation can worsen your condition. This medicine is recommended for individuals 18 years and above.

Side Effects: Common side effects may include:

• Headache, dizziness, and sleepiness.
• Cough (dry, persistent).
• Ankle swelling.
• Decreased blood pressure (hypotension).
• Increased potassium levels in the blood (hyperkalaemia).
• Nausea, upset stomach, and back pain. Serious side effects, though rare, can include severe dizziness or fainting, angioedema (swelling of the face, lips, tongue, or throat), chest pain, irregular heartbeat, or signs of liver/kidney problems.

Precautions:

• Contraindications: Do not take if you are allergic to amlodipine, perindopril, or any ACE inhibitors, have a history of angioedema, very low blood pressure, severe heart failure after a heart attack, or serious narrowing of heart valves.
• Pregnancy and Breastfeeding: This medicine is contraindicated during pregnancy, especially in the second and third trimesters, and should not be used by breastfeeding mothers.
• Monitoring: Regular monitoring of blood pressure, kidney function, and electrolyte levels (especially potassium) is advisable.
• Interactions: Inform your doctor about all other medications, especially potassium-sparing diuretics, potassium supplements, lithium, or injectable gold, as interactions may occur.
• Other Conditions: Exercise caution and inform your doctor if you have kidney or liver disease, diabetes, severe low blood pressure, or are undergoing specific medical procedures. It may cause dizziness; avoid driving or operating machinery until you know how it affects you.

Storage:

• Store below 25°C.
• Keep in a cool, dry place, away from moisture, heat, and direct sunlight.
• Keep out of sight and reach of children.

Here are frequently asked questions about COVERSYL AM 4/10 MG TABLET:

What is COVERSYL AM 4/10 MG TABLET used for?

COVERSYL AM 4/10 MG TABLET is primarily used to treat hypertension (high blood pressure) when a single blood pressure-lowering medication is not sufficient. It helps relax blood vessels, improve blood flow, and reduce the strain on the heart, thereby lowering the risk of heart attack and stroke. It may also be used in stable coronary artery disease.

How does COVERSYL AM 4/10 MG TABLET work?

This medicine is a combination of two active ingredients: Amlodipine (10 mg) and Perindopril (4 mg). Amlodipine is a calcium channel blocker that relaxes blood vessels by preventing calcium from entering heart and blood vessel cells, which eases blood flow. Perindopril is an ACE (Angiotensin-Converting Enzyme) inhibitor that works by blocking the production of angiotensin II, a substance that narrows blood vessels. This action also helps relax and widen blood vessels, making it easier for the heart to pump blood. Together, they provide a synergistic effect for comprehensive blood pressure control.

What is the usual dosage for COVERSYL AM 4/10 MG TABLET?

COVERSYL AM 4/10 MG TABLET should be taken in the dose and duration advised by your doctor. It is typically taken once daily, preferably on an empty stomach, and at the same time each day for consistency. Do not chew, crush, or break the tablet.

What are the possible side effects of COVERSYL AM 4/10 MG TABLET?

Common side effects include ankle swelling, headache, tiredness, palpitations, increased potassium levels in the blood, sleepiness, cough, taste change, flushing, decreased blood pressure, upset stomach, erectile dysfunction, and eczema. More serious side effects can include severe dizziness or fainting due to low blood pressure, chest pain, irregular heartbeat, kidney problems, yellowing of the skin or eyes (liver issues), or a persistent cough. Report any sudden swelling of the face or severe abdominal pain to your doctor immediately.

Is COVERSYL AM 4/10 MG TABLET safe during pregnancy or breastfeeding?

COVERSYL AM 4/10 MG TABLET is considered unsafe during pregnancy, as there is definite evidence of risk to the developing baby, especially during the second and third trimesters. If you become pregnant while taking this medicine, discontinue use as soon as possible and consult your doctor. For breastfeeding, limited human data suggests it is probably safe to use if prescribed by a doctor, but it is generally not advised for breastfeeding mothers as it can pass into breastmilk in trace levels and may harm the baby, particularly newborns or premature infants. Always consult your doctor for advice if pregnant or breastfeeding.

Can COVERSYL AM 4/10 MG TABLET be taken with other medications?

Care should be taken when taking COVERSYL AM 4/10 MG TABLET with certain other medications. There is a risk of increased blood potassium levels if used with potassium-sparing diuretics (like spironolactone, amiloride), potassium supplements, or other medicines that can increase serum potassium (such as indomethacin, heparin, cyclosporine). Diuretics may also increase the risk of low blood pressure. Non-steroidal anti-inflammatory drugs (NSAIDs) can decrease its blood pressure-lowering effect and increase the risk of kidney issues. Other medications that interact include those for mental disorders (lithium), abnormal cholesterol (simvastatin), and certain arthritis treatments (injectable gold). Always inform your doctor about all medicines, supplements, or herbal products you are currently taking.

What precautions should be taken while using COVERSYL AM 4/10 MG TABLET?

Avoid consuming alcohol, as it is unsafe with this medication. Exercise caution if you have kidney or liver disease, as dose adjustments may be necessary. This medicine may cause dizziness or weakness due to low blood pressure, so avoid driving or operating machinery until you know how it affects you. Patients with very low blood pressure, severe heart failure after a heart attack, serious narrowing of heart valves, or allergies to amlodipine, perindopril, or other ACE inhibitors should not take this medicine. Inform your doctor if you have diabetes, heart problems, or are on a salt-restricted diet.

What happens if a dose is missed?

If you miss a dose of COVERSYL AM 4/10 MG TABLET, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one.

How should COVERSYL AM 4/10 MG TABLET be stored?

Store COVERSYL AM 4/10 MG TABLET below 25°C. Keep the tablets in their original packaging until it is time to take them, in a cool, dry place away from moisture, heat, and direct sunlight. Keep it out of reach of children.