Lupin Zrx 60 Tablet

LUPIN ZRX 60 TABLET

Lupin ZXR 60 Tablet is an oral antidiabetic medication manufactured by Lupin Ltd., commonly known as Lupin ZXR 60 Tablet MR or Lupin Z XR 60 Tablet.

• Composition: Each tablet contains 60 mg of Gliclazide.

• Uses: This medicine is primarily prescribed for adults with type 2 diabetes mellitus to manage blood sugar levels. It is used when diet, exercise, and weight reduction alone are insufficient to control blood glucose. It can be used as a standalone treatment or in combination with other antidiabetic medicines like Metformin.

• Dosage and Administration: Lupin ZXR 60 Tablet is taken orally, typically once daily with breakfast or the first main meal. The tablet should be swallowed whole with water and not crushed, chewed, or broken. The specific dosage and duration are determined by a healthcare professional based on individual response and condition severity. Regular and consistent administration at the same time each day is recommended for optimal results.

• Side Effects:

  • Common: Hypoglycaemia (low blood sugar), nausea, vomiting, diarrhoea, dyspepsia (indigestion), headache, dizziness, stomach pain, and weight gain.
  • Serious: Rare but severe allergic reactions (skin rash, swelling of face/lips/tongue/throat causing difficulty breathing) or signs of liver problems (fever, yellowing of skin/eyes, weakness, fatigue, loss of appetite) require immediate medical attention.

• Precautions:

  • There is a risk of hypoglycaemia, especially with alcohol consumption, concurrent use of other antidiabetic medicines, or missed/delayed meals. Patients should carry sugary snacks or fruit juice to manage low blood sugar.
  • It is contraindicated in patients with type 1 diabetes, diabetic ketoacidosis, severe kidney or liver disease, allergy to gliclazide, pregnancy, breastfeeding, and G6PD deficiency.
  • Alcohol consumption is unsafe with this medicine.
  • Caution is advised while driving or operating machinery due to potential blood sugar fluctuations.

• Storage: Store in a cool and dry place, away from direct sunlight. Maintain storage at room temperature, typically between 10°C to 25°C or below 30°C. Keep out of the sight and reach of children.

Here are frequently asked questions about LUPIN ZRX 60 TABLET:

What is LUPIN ZRX 60 TABLET used for?

LUPIN ZRX 60 TABLET is primarily used to manage blood sugar levels in adults with type 2 diabetes mellitus. It is an oral antidiabetic medication belonging to the sulfonylurea category. It can be prescribed alone or in combination with other antidiabetic medicines, such as metformin, when diet, exercise, and weight reduction alone are not sufficient to control blood glucose levels. This medicine is not for managing type 1 diabetes or diabetic ketoacidosis.

How does LUPIN ZRX 60 TABLET work?

LUPIN ZRX 60 TABLET contains gliclazide (60 mg) as its active ingredient. Gliclazide primarily works by stimulating the beta-cells of the pancreas to release more insulin. This increased insulin helps lower blood glucose levels by promoting the uptake of glucose into cells. It may also enhance the sensitivity of tissues to insulin and suppress glucose production in the liver.

What is the usual dosage for LUPIN ZRX 60 TABLET?

The usual starting dose for adults is typically 40 to 80 mg once daily, taken with breakfast or the first main meal of the day. Your doctor will determine the appropriate dose based on your condition's severity and your response to the medication. The tablet should be swallowed whole with a glass of water and not crushed, chewed, or broken. The maximum recommended dose is 320 mg per day, which can be taken in divided doses.

What are the possible side effects of LUPIN ZRX 60 TABLET?

Common side effects include hypoglycemia (low blood sugar), nausea, vomiting, diarrhea, indigestion (dyspepsia), headache, dizziness, and weight gain. Symptoms of hypoglycemia can include shakiness, intense hunger, sweating, weakness, irregular heartbeat, tremors, cold sweats, and anxiety. If you experience severe allergic reactions (like skin rash, swelling of the face or throat causing difficulty breathing) or signs of liver problems (fever, yellowing of skin or eyes), contact your doctor immediately.

Is LUPIN ZRX 60 TABLET safe during pregnancy or breastfeeding?

LUPIN ZRX 60 TABLET is not recommended for use during pregnancy as it may harm the unborn baby, and there is limited safety data available. If you are pregnant or become pregnant while taking this medicine, inform your doctor immediately. Similarly, it is considered unsafe during breastfeeding, as data suggests the drug may cause toxicity to the baby, or it is unknown if it passes into breast milk.

Can LUPIN ZRX 60 TABLET be taken with other medications?

LUPIN ZRX 60 TABLET can interact with several medications. Taking it with other antidiabetic medicines, beta-blockers (e.g., propranolol, metoprolol), or ACE inhibitors (e.g., lisinopril, enalapril) can increase the risk of low blood sugar. Conversely, corticosteroids (e.g., prednisone) and thiazide diuretics (e.g., hydrochlorothiazide) can diminish its blood sugar-lowering effect. Concomitant use with miconazole (for fungal infections) or phenylbutazone is not recommended due to potential severe hypoglycemia. Always inform your doctor about all prescription, over-the-counter, herbal, and supplement medications you are taking to avoid potential interactions.

What precautions should be taken while on LUPIN ZRX 60 TABLET?

It is important to avoid alcohol consumption while taking this medicine as it can increase the risk of hypoglycemia. You should also be cautious when driving or operating machinery if you experience dizziness or blurred vision due to fluctuations in blood sugar. Patients with severe kidney or liver disease should use this medication with caution, as it may require dose adjustments or might be contraindicated. Always carry a fast-acting source of glucose, like sugary food or fruit juice, to treat sudden low blood sugar. Regular monitoring of blood sugar levels, a balanced diet, and regular exercise are crucial for effective diabetes management.

What happens if a dose of LUPIN ZRX 60 TABLET is missed?

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.

How should LUPIN ZRX 60 TABLET be stored?

LUPIN ZRX 60 TABLET should be stored in a cool and dry place, away from direct sunlight. It should be kept at room temperature, typically between 10ºC and 25ºC or below 30ºC. Always keep this medicine out of the sight and reach of children.